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01-06-2014 | Biomechanics (M Silva and P Zysset, Section Editors)

Ultrasound to Assess Bone Quality

Authors: Kay Raum, Quentin Grimal, Peter Varga, Reinhard Barkmann, Claus C. Glüer, Pascal Laugier

Published in: Current Osteoporosis Reports | Issue 2/2014

Abstract

Bone quality is determined by a variety of compositional, micro- and ultrastructural properties of the mineralized tissue matrix. In contrast to X-ray-based methods, the interaction of acoustic waves with bone tissue carries information about elastic and structural properties of the tissue. Quantitative ultrasound (QUS) methods represent powerful alternatives to ionizing x-ray based assessment of fracture risk. New in vivo applicable methods permit measurements of fracture-relevant properties, [eg, cortical thickness and stiffness at fragile anatomic regions (eg, the distal radius and the proximal femur)]. Experimentally, resonance ultrasound spectroscopy and acoustic microscopy can be used to assess the mesoscale stiffness tensor and elastic maps of the tissue matrix at microscale resolution, respectively. QUS methods, thus, currently represent the most promising approach for noninvasive assessment of components of fragility beyond bone mass and bone microstructure providing prospects for improved assessment of fracture risk.

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Title: Ultrasound to Assess Bone Quality
Authors: Kay Raum
Quentin Grimal
Peter Varga
Reinhard Barkmann
Claus C. Glüer
Pascal Laugier
Publication date: 01-06-2014
Publisher: Springer US
Published in: Current Osteoporosis Reports / Issue 2/2014
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI: https://doi.org/10.1007/s11914-014-0205-4

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Ultrasound to Assess Bone Quality

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