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Published in: Insights into Imaging 1/2012

Open Access 01-02-2012 | Original Article

Ultrafast imaging of the entire chest without ECG synchronisation or beta-blockade: to what extent can we analyse the coronary arteries?

Authors: Maxime de Malherbe, Alain Duhamel, Nunzia Tacelli, Anne-Lise Hachulla, François Pontana, Jean-Baptiste Faivre, Jacques Remy, Martine Remy-Jardin

Published in: Insights into Imaging | Issue 1/2012

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Abstract

Objectives

To evaluate the accessibility of coronary arteries from chest CT examinations acquired without ECG gating or beta-blockade.

Materials and methods

Two hundred forty-two patients (median heart rate: 81.7 bpm) underwent a non-ECG-gated CT examination with high pitch and high temporal resolution. Image analysis was obtained by consensus between two readers.

Results

The percentage of accessible segments was 88% at the proximal level (i.e. 4 segments), 75% at the proximal and mid-segment level (i.e. 7 segments), and 61% and 48% when considering 10 and 15 segments, respectively. The mean (± SD) number of accessible segments per patient was 3.5 ± 0.78 and 5.2 ± 1.50 when considering four and seven segments per patient, respectively. The percentage of patients with four segments accessible was 67% (126/242), decreasing to 23% (55/242) with seven segments accessible and 3% (7/242) with ten segments accessible, while the entire coronary artery tree was not accessible for any of the patients. No significant difference was found in the patients’ mean hearts with four, seven, or ten accessible segments (P = 0.4897).

Conclusion

Diagnostic image quality was attainable at the level of proximal segments in 67% of patients, while proximal and mid-coronary segments were accessible in 23% of patients.
Main Messages
High-pitch and high-temporal resolution scanning modes make accessible proximal coronary arteries on non ECG-gated chest CT angiograms
• It is not necessary to administer beta-blockers to achieve good results.
• Tobacco-related cardiovascular disorders could benefit from this scanning mode.
Literature
1.
go back to reference White CS, Kuo D, Kelemen M, Jain V, Musk A, Zaidi E, Read K, Sliker C, Prasad R (2005) Chest pain evaluation in the emergency department: can MDCT provide a comprehensive evaluation? AJR 185:533–540PubMedCrossRef White CS, Kuo D, Kelemen M, Jain V, Musk A, Zaidi E, Read K, Sliker C, Prasad R (2005) Chest pain evaluation in the emergency department: can MDCT provide a comprehensive evaluation? AJR 185:533–540PubMedCrossRef
2.
go back to reference Delhaye D, Remy-Jardin M, Rozel C, Dusson C, Wurtz A, Delannoy-Deken V, Duhamel A, Remy J (2007) Coronary artery imaging during preoperative CT staging: preliminary experience with 64-slice multidetector CT in 99 patients. Eur Radiol 17:591–602PubMedCrossRef Delhaye D, Remy-Jardin M, Rozel C, Dusson C, Wurtz A, Delannoy-Deken V, Duhamel A, Remy J (2007) Coronary artery imaging during preoperative CT staging: preliminary experience with 64-slice multidetector CT in 99 patients. Eur Radiol 17:591–602PubMedCrossRef
3.
go back to reference Pansini V, Remy-Jardin M, Tacelli N, Faivre JB, Flohr T, Deken V, Duhamel A, Remy J (2008) Screening for coronary artery disease in respiratory patients: comparison of single- and dual-source CT in patients with a heart rate above 70 bpm. Eur Radiol 18:2108–2119PubMedCrossRef Pansini V, Remy-Jardin M, Tacelli N, Faivre JB, Flohr T, Deken V, Duhamel A, Remy J (2008) Screening for coronary artery disease in respiratory patients: comparison of single- and dual-source CT in patients with a heart rate above 70 bpm. Eur Radiol 18:2108–2119PubMedCrossRef
4.
go back to reference Fremont B, Pacouret G, Jacobi D, Puglisi R, Charbonnier B, de Labriolle A (2008) Prognostic value of echocardiographic right ventricular end-diastolic diameter ratio in patients with acute pulmonary embolism. Chest 133:358–362PubMedCrossRef Fremont B, Pacouret G, Jacobi D, Puglisi R, Charbonnier B, de Labriolle A (2008) Prognostic value of echocardiographic right ventricular end-diastolic diameter ratio in patients with acute pulmonary embolism. Chest 133:358–362PubMedCrossRef
5.
go back to reference Gerhardsson de Verdier M (2008) The big three concept: a way to tackle the health care crisis? Proc Am Thorac Soc 5:800–805PubMedCrossRef Gerhardsson de Verdier M (2008) The big three concept: a way to tackle the health care crisis? Proc Am Thorac Soc 5:800–805PubMedCrossRef
6.
go back to reference Goetti R, Baumüller S, Feuchtner G, Stolzmann P, Karlo C, Alkhadi H, Leschka S (2010) High-pitch dual-source CT angiography of the thoracic and abdominal aorta: is simultaneous coronary artery assessment possible? AJR 194:938–944PubMedCrossRef Goetti R, Baumüller S, Feuchtner G, Stolzmann P, Karlo C, Alkhadi H, Leschka S (2010) High-pitch dual-source CT angiography of the thoracic and abdominal aorta: is simultaneous coronary artery assessment possible? AJR 194:938–944PubMedCrossRef
7.
go back to reference Tacelli N, Remy-Jardin M, Flohr T, Faivre JB, Delannoy V, Duhamel A, Remy J (2010) Dual-source chest CT angiography with high temporal resolution and high pitch modes: evaluation of image quality in 140 patients. Eur Radiol 20:1188–1196PubMedCrossRef Tacelli N, Remy-Jardin M, Flohr T, Faivre JB, Delannoy V, Duhamel A, Remy J (2010) Dual-source chest CT angiography with high temporal resolution and high pitch modes: evaluation of image quality in 140 patients. Eur Radiol 20:1188–1196PubMedCrossRef
9.
go back to reference Austen WG, Edwards JE, Frye RL et al (1975) Reporting system on patients evaluated for coronary artery disease: report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51(suppl 4):5–40PubMedCrossRef Austen WG, Edwards JE, Frye RL et al (1975) Reporting system on patients evaluated for coronary artery disease: report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51(suppl 4):5–40PubMedCrossRef
10.
go back to reference Matt D, Scheffel H, Leschka S et al (2007) Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR 189:567–573PubMedCrossRef Matt D, Scheffel H, Leschka S et al (2007) Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR 189:567–573PubMedCrossRef
11.
go back to reference Seifarth H, Puesken M, Kalafut JF et al (2009) Introduction of an individually optimize protocol for the injection of contrast medium for coronary CT angiography. Eur Radiol 19:2373–2382PubMedCrossRef Seifarth H, Puesken M, Kalafut JF et al (2009) Introduction of an individually optimize protocol for the injection of contrast medium for coronary CT angiography. Eur Radiol 19:2373–2382PubMedCrossRef
12.
go back to reference Husmann L, Herzog BA, Burkhard N et al (2009) Low-dose coronary CT angiography with prospective ECG triggering: validation of a contrast material protocol adapted to body mass index. AJR 193:802–806PubMedCrossRef Husmann L, Herzog BA, Burkhard N et al (2009) Low-dose coronary CT angiography with prospective ECG triggering: validation of a contrast material protocol adapted to body mass index. AJR 193:802–806PubMedCrossRef
13.
go back to reference Bamberg F, Sommer WH, Schenzle JC et al (2010) Systolic acquisition of coronary dual-source computed tomography angiography: feasibility in an unselected patient population. Eur Radiol 20:1331–1336PubMedCrossRef Bamberg F, Sommer WH, Schenzle JC et al (2010) Systolic acquisition of coronary dual-source computed tomography angiography: feasibility in an unselected patient population. Eur Radiol 20:1331–1336PubMedCrossRef
14.
go back to reference Scheffel H, Alkadhi H, Plass A et al (2006) Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol 16:2739–2747PubMedPubMedCentralCrossRef Scheffel H, Alkadhi H, Plass A et al (2006) Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol 16:2739–2747PubMedPubMedCentralCrossRef
15.
go back to reference Johnson TR, Nikolaou K, Becker A et al (2006) Dual-source CT cardiac imaging:initial experience. Eur Radiol 16:1409–1415PubMedCrossRef Johnson TR, Nikolaou K, Becker A et al (2006) Dual-source CT cardiac imaging:initial experience. Eur Radiol 16:1409–1415PubMedCrossRef
16.
go back to reference Achenbach S, Ropers D, Kuettner A et al (2006) Contrast-enhanced coronary artery visualization by dual-source computed tomography–initial experience. Eur J Radiol 57:331–335PubMedCrossRef Achenbach S, Ropers D, Kuettner A et al (2006) Contrast-enhanced coronary artery visualization by dual-source computed tomography–initial experience. Eur J Radiol 57:331–335PubMedCrossRef
17.
go back to reference Choi EK, Choi SI, Rivera JJ, Nasir K, Chang SA, Chun EJ, Kim HK, Choi DJ, Blumenthal RS, Chang HJ (2008) Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals. J Am Coll Cardiol 52:357–365PubMedCrossRef Choi EK, Choi SI, Rivera JJ, Nasir K, Chang SA, Chun EJ, Kim HK, Choi DJ, Blumenthal RS, Chang HJ (2008) Coronary computed tomography angiography as a screening tool for the detection of occult coronary artery disease in asymptomatic individuals. J Am Coll Cardiol 52:357–365PubMedCrossRef
18.
go back to reference Burgstahler C, Reimann A, Brodoefel H et al (2009) Quantitative parameters to compare image quality of noninvasive coronary angiography with 16-slice, 64-slice and dual-source computed tomography. Eur Radiol 19:584–590PubMedCrossRef Burgstahler C, Reimann A, Brodoefel H et al (2009) Quantitative parameters to compare image quality of noninvasive coronary angiography with 16-slice, 64-slice and dual-source computed tomography. Eur Radiol 19:584–590PubMedCrossRef
19.
go back to reference Halpern EJ, Levin DC, Zhang S, Takakuwa KM (2009) Comparison of image quality and arterial enhancement with a dedicated coronary CTA protocol versus a triple rule-out coronary CTA protocol. Acad Radiol 16:1039–1048PubMedCrossRef Halpern EJ, Levin DC, Zhang S, Takakuwa KM (2009) Comparison of image quality and arterial enhancement with a dedicated coronary CTA protocol versus a triple rule-out coronary CTA protocol. Acad Radiol 16:1039–1048PubMedCrossRef
20.
go back to reference Delhaye D, Remy-Jardin M, Salem R, Teisseire A, Khalil C, Delannoy-Deken V, Duhamel A, Remy J (2007) Coronary imaging quality in routine ECG-gated multidetector CT examinations of the entire thorax: preliminary experience with a 64-slice CT system in 133 patients. Eur Radiol 17:902–910PubMedCrossRef Delhaye D, Remy-Jardin M, Salem R, Teisseire A, Khalil C, Delannoy-Deken V, Duhamel A, Remy J (2007) Coronary imaging quality in routine ECG-gated multidetector CT examinations of the entire thorax: preliminary experience with a 64-slice CT system in 133 patients. Eur Radiol 17:902–910PubMedCrossRef
21.
go back to reference Egred M, Shaw S, Mohammad B, Waitt P, Radrigues E (2005) Under-use of beta-blockers in patients with ischemic heart disease and concomitant chronic obstructive pulmonary disease. QJM 98:493–497PubMedCrossRef Egred M, Shaw S, Mohammad B, Waitt P, Radrigues E (2005) Under-use of beta-blockers in patients with ischemic heart disease and concomitant chronic obstructive pulmonary disease. QJM 98:493–497PubMedCrossRef
22.
go back to reference Cazzola M, Matera MG (2008) Beta-blockers are safe in patients with chronic obstructive pulmonary disease, but only with caution. Am J Respir Crit Care Med 178:661–662PubMedCrossRef Cazzola M, Matera MG (2008) Beta-blockers are safe in patients with chronic obstructive pulmonary disease, but only with caution. Am J Respir Crit Care Med 178:661–662PubMedCrossRef
Metadata
Title
Ultrafast imaging of the entire chest without ECG synchronisation or beta-blockade: to what extent can we analyse the coronary arteries?
Authors
Maxime de Malherbe
Alain Duhamel
Nunzia Tacelli
Anne-Lise Hachulla
François Pontana
Jean-Baptiste Faivre
Jacques Remy
Martine Remy-Jardin
Publication date
01-02-2012
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 1/2012
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-011-0133-0

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