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European Radiology
Published in: European Radiology 3/2009

01-03-2009 | Cardiac

Quantitative parameters to compare image quality of non-invasive coronary angiography with 16-slice, 64-slice and dual-source computed tomography

Authors: Christof Burgstahler, Anja Reimann, Harald Brodoefel, Ulrike Daferner, Tina Herberts, Ilias Tsiflikas, Christoph Thomas, Tanja Drosch, Stephen Schroeder, Martin Heuschmid

Published in: European Radiology | Issue 3/2009

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Abstract

Multi-slice computed tomography (MSCT) is a non-invasive modality to visualize coronary arteries with an overall good image quality. Improved spatial and temporal resolution of 64-slice and dual-source computed tomography (DSCT) scanners are supposed to have a positive impact on diagnostic accuracy and image quality. However, quantitative parameters to compare image quality of 16-slice, 64-slice MSCT and DSCT are missing. A total of 256 CT examinations were evaluated (Siemens, Sensation 16: n = 90; Siemens Sensation 64: n = 91; Siemens Definition: n = 75). Mean Hounsfield units (HU) were measured in the cavum of the left ventricle (LV), the ascending aorta (Ao), the left ventricular myocardium (My) and the proximal part of the left main (LM), the left anterior descending artery (LAD), the right coronary artery (RCA) and the circumflex artery (CX). Moreover, the ratio of intraluminal attenuation (HU) to myocardial attenuation was assessed for all coronary arteries. Clinical data [body mass index (BMI), gender, heart rate] were accessible for all patients. Mean attenuation (CA) of the coronary arteries was significantly higher for DSCT in comparison to 64- and 16-slice MSCT within the RCA [347 ± 13 vs. 254 ± 14 (64-MSCT) vs. 233 ± 11 (16-MSCT) HU], LM (362 ± 11/275 ± 12/262 ± 9), LAD (332 ± 17/248 ± 19/219 ± 14) and LCX (310 ± 12/210 ± 13/221 ± 10, all p < 0.05), whereas there was no significant difference between DSCT and 64-MSCT for the LV, the Ao and My. Heart rate had a significant impact on CA ratio in 16-slice and 64-slice CT only (p < 0.05). BMI had no impact on the CA ratio in DSCT only (p < 0.001). Improved spatial and temporal resolution of dual-source CT is associated with better opacification of the coronary arteries and a better contrast with the myocardium, which is independent of heart rate. In comparison to MSCT, opacification of the coronary arteries at DSCT is not affected by BMI. The main advantage of DSCT lies with the heart rate independency, which might have a positive impact on the diagnostic accuracy.
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Metadata
Title
Quantitative parameters to compare image quality of non-invasive coronary angiography with 16-slice, 64-slice and dual-source computed tomography
Authors
Christof Burgstahler
Anja Reimann
Harald Brodoefel
Ulrike Daferner
Tina Herberts
Ilias Tsiflikas
Christoph Thomas
Tanja Drosch
Stephen Schroeder
Martin Heuschmid
Publication date
01-03-2009
Publisher
Springer-Verlag
Published in
European Radiology / Issue 3/2009
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-008-1201-9

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