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Published in: Trials 1/2020

Open Access 01-12-2020 | Type 2 Diabetes | Study protocol

Protocol for a randomised controlled trial to investigate the effect of home- and gym-based resistance exercise training on glycaemic control, body composition and muscle strength

Authors: Ebaa Al Ozairi, Dalal Alsaeed, Dennis Taliping, Mohamad Jalali, Abeer El Samad, Anant Mashankar, Etab Taghadom, Nicola Guess, Jason M. R. Gill, Naveed Sattar, Cindy Gray, Paul Welsh, Stuart R. Gray

Published in: Trials | Issue 1/2020

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Abstract

Background

Resistance exercise is known to be effective in reducing glycated haemoglobin (HbA1c) in people with type 2 diabetes. However, studies, so far, have employed supervised resistance exercise in a laboratory or gym facility which limits the future translation of such exercise in to clinical practice and recommendations. Our primary aim, therefore, is to test the hypothesis, in a randomized controlled trial, that home-based resistance exercise training and gym-based resistance exercise training both reduce HbA1c levels in people with type 2 diabetes compared to control. We will also investigate the effects of home- and gym-based resistance exercise training on muscle strength and body composition.

Methods

The current study is a three-arm randomised controlled trial which will be conducted with 150 eligible people with type 2 diabetes to compare home-and gym-based resistance exercise training with usual care in Kuwait. The interventions will be delivered by exercise specialists and last for 32 weeks. The primary outcomes are HbA1c with secondary outcomes measuring muscle function, body composition, physical activity and quality of life.

Discussion

Ethical approval has been granted by the Dasman Diabetes Institute ethical review committee (RA/197/2019). Study findings will be disseminated through presentation at scientific conferences and in scientific journals.

Trial registration

NCT04136730: Retrospectively registered on 21 October 2019
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Metadata
Title
Protocol for a randomised controlled trial to investigate the effect of home- and gym-based resistance exercise training on glycaemic control, body composition and muscle strength
Authors
Ebaa Al Ozairi
Dalal Alsaeed
Dennis Taliping
Mohamad Jalali
Abeer El Samad
Anant Mashankar
Etab Taghadom
Nicola Guess
Jason M. R. Gill
Naveed Sattar
Cindy Gray
Paul Welsh
Stuart R. Gray
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Type 2 Diabetes
Published in
Trials / Issue 1/2020
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-020-04480-2

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