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Published in: Acta Diabetologica 11/2018

01-11-2018 | Original Article

Type 2 diabetes and treatment intensification in primary care in Finland

Authors: Leo Niskanen, Jarmo Hahl, Jari Haukka, Elli Leppä, Tatu Miettinen, Vasili Mushnikov, Raija Sipilä, Nadia Tamminen, Pia Vattulainen, Pasi Korhonen

Published in: Acta Diabetologica | Issue 11/2018

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Abstract

Aim

To identify how the electronic health record (EHR) systems and national registers can be used for research purposes. We focused on how the primary care physicians adhere to clinical guidelines.

Methods

Study population included incident type 2 diabetes patients from four selected regions. Data were collected in two phases. At the first phase study cohort was identified using the prescription registers of the Social Insurance Institution (SII) and EHR systems used within the study regions. At second phase, data were collected from SII’s registers, local EHR systems, the hospital discharge and the primary care registers of National Institute for Health and Welfare.

Results

Metformin was the most common choice as first drug. Among all study patients, 8375 (76.0%) started metformin monotherapy or combinations. The treatment was intensified at variable levels of HbA1c depending on the area. DPP4-inhibitors were by far the most common agent for treatment intensification. Sulphonylureas were used less often than basal insulin as the second-line agent. The use of DPP4-inhibitors increased between years 2009–2010, when first DPP4-inhibitor received reimbursement and this class became dominant drug for treatment intensification increasingly thereafter.

Conclusions

The EHR systems and national registers can be used for research purposes in Finland. The realization of diabetes treatment national guidelines are followed in primary care to a large extent. However, the subsequent intensification of therapy was delayed and occurred at elevated Hba1c levels.
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Metadata
Title
Type 2 diabetes and treatment intensification in primary care in Finland
Authors
Leo Niskanen
Jarmo Hahl
Jari Haukka
Elli Leppä
Tatu Miettinen
Vasili Mushnikov
Raija Sipilä
Nadia Tamminen
Pia Vattulainen
Pasi Korhonen
Publication date
01-11-2018
Publisher
Springer Milan
Published in
Acta Diabetologica / Issue 11/2018
Print ISSN: 0940-5429
Electronic ISSN: 1432-5233
DOI
https://doi.org/10.1007/s00592-018-1199-7

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