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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2018

Open Access 01-12-2018 | Case Report

Two rare cases of synchronous and metachronous colonic metastases in patients with advanced gastric cancer

Authors: Wei-Chih Su, Hsiang-Lin Tsai, Chun-Chieh Wu, Shan-Yin Tsai, Yung-Sung Yeh, Cheng-Jen Ma, Jaw-Yuan Wang

Published in: World Journal of Surgical Oncology | Issue 1/2018

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Abstract

Background

Patients with advanced gastric cancer (GC) may ultimately die because GC mostly leads to synchronous or metachronous metastasis. However, colonic metastasis of GC is extremely rare. According to a PubMed search of papers published from May 1968 to March 2017, only 21 patients with GC (10 patients from 10 case reports and 11 patients from a retrospective study) have been found to have colonic metastasis. In this report, we present two cases of synchronous and metachronous colonic metastases of advanced GC.

Case presentation

Two patients with advanced GC received a diagnosis of colonic metastasis based on colonoscopic findings and computed tomography images, and the diagnosis was confirmed through pathological immunohistochemical analysis. Herein, we describe the management and outcomes of these metastases.

Conclusions

Submucosal swelling and segmental bowel wall thickening observed through colonoscopy in patients with advanced GC might indicate colonic metastasis.
Literature
1.
2.
3.
Lee IH, Lee JE, Byeon SW, Lee HJ, Huo SM, Yoon SB, et al. A case of advanced gastric cancer presenting as multiple colonic lymphoid hyperplasia. Korean J Gastroenterol. 2015;66(4):221–6. [Article in Korean]CrossRefPubMed
4.
5.
Metayer P, Antoneitti M, Oumrani M, et al. Metastases of a gastric adenocarcinoma presenting as colonic polyposis. Report of a case. Dis Colon Rectum. 1991;34:622–3.CrossRefPubMed
6.
Ogiwara H, Konno H, Kitayama Y, et al. Metastases from gastric adenocarcinoma presenting as multiple colonic polyps: report of a case. Surg Today. 1994;24:473–5.CrossRefPubMed
7.
Tiszlavicz L. Stomach cancer metastasizing into a solitary adenomatous colonic polyp. Orv Hetil. 1990;131:1259–61. [Article in Hungarian]PubMed
8.
Dohden K, et al. Metastases from gastric carcinoma to esophagus, duodenum and large intestine in the form of polyposis, report of a case. Stomach Intestine (Tokyo). 2002;37:1238–42. [Article in Japanese]
9.
Lee HC, Yang MT, Lin KY, Tu HY, Zhang TA, Chen PH. Metastases from gastric carcinoma to colon in the form of multiple flat elevated lesions: a case report. Kaohsiung J Med Sci. 2004;20:552–7.CrossRefPubMed
10.
Nakamura H, Fu K, Fukui H, Hurlstone DP, Kaji Y, Ishikawa T, Fujimori T. A solitary colonic metastasis from gastric cancer detected at an early stage. Gastrointest Endosc. 2008;67(6):1000–4.CrossRefPubMed
11.
Pace U, Contino G, Chiappa A, Bertani E, Bianchi PP, Facio N, et al. Metachronous colon metastases from gastric adenocarcinoma: a case report. Case Reports in Oncology. 2009;2(2):92–6.CrossRefPubMedPubMedCentral
12.
Fujimoto D, Hirono Y, Goi Y, Yamaguchi A. Sigmoid colonic metastasis by lymphatic spread occurring with unilateral Krukenberg tumor considered to be caused by stage IA early gastric cancer: a case report. Oncol Lett. 2016;11(1):668–72.CrossRefPubMed
13.
Jang HJ, Lim HK, Kim HS, et al. Intestinal metastases from gastric adenocarcinoma: helical CT findings. J Comput Assist Tomogr. 2001;25:61–7.CrossRefPubMed
14.
Duarte I, Llanos O. Pattern of metastases in intestinal and diffuse types of carcinoma of the stomach. Hum Pathol. 1981;12:237–42.CrossRefPubMed
15.
Fernandes T, Oliveira MI, Castro R, Araújo B, Viamonte B, Cunha R. Bowel wall thickening at CT: simplifying the diagnosis. Insights Imaging. 2014;5(2):195–208.CrossRefPubMedPubMedCentral
16.
Werling RW, Yaziji H, Bacchi CE, et al. CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin. Am J Surg Pathol. 2003;27:303–10.CrossRefPubMed
17.
Bayrak R, Haltas H, Yenidunya S. The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7−/20+ phenotype is more specific than CDX2 antibody. Diagn Pathol. 2012;7:9.CrossRefPubMedPubMedCentral
Metadata
Title
Two rare cases of synchronous and metachronous colonic metastases in patients with advanced gastric cancer
Authors
Wei-Chih Su
Hsiang-Lin Tsai
Chun-Chieh Wu
Shan-Yin Tsai
Yung-Sung Yeh
Cheng-Jen Ma
Jaw-Yuan Wang
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2018
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-018-1323-8

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