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Open Access 01-12-2021 | Turner's Syndrome | Review

Delayed pubarche

Authors: Francesco Baldo, Egidio Barbi, Gianluca Tornese

Published in: Italian Journal of Pediatrics | Issue 1/2021

Abstract

In healthy adolescents, delayed pubarche is generally a benign condition that is caused by a physiological discrepancy between gonadarche and adrenarche. In presence of other clinical signs and symptoms, delayed pubarche can be caused by single or multiple hormones deficiency (such as adrenal insufficiency, panhypopituitarism and hypothyroidism) and/or genetic conditions (Turner syndrome, androgen insensitivity syndrome). Exposition to endocrine disruptors has also been described as a possible cause of delay of pubic hair development. Basic blood tests, karyotype and first level imaging studies are helpful in the differential diagnosis.

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Title: Delayed pubarche
Authors: Francesco Baldo
Egidio Barbi
Gianluca Tornese
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Turner's Syndrome
Panhypopituitarism
Androgens
Published in: Italian Journal of Pediatrics / Issue 1/2021
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/s13052-021-01134-0

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Delayed pubarche

Abstract

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Abstract

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