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Breast Cancer Research
Published in: Breast Cancer Research 1/2000

01-03-2000 | Oral presentation

Tumour-selective transcriptional targeting for breast cancer gene therapy

Author: HC Hurst

Published in: Breast Cancer Research | Special Issue 1/2000

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Excerpt

One of the most attractive ways of targeting gene therapy is by exploitation of the transcriptional regulatory elements of genes which display tissue- or tumour-selective patterns of expression. In our Unit we have focused on identifying the key regulatory elements in a small number of genes known to be overexpressed in breast tumours. Shortly, however, the power of expression profiling by chip technology will expand the range of candidate genes enormously. This will also allow much more specific expression-targeting constructs to be developed by `mixing and matching' elements from different genes. …
Metadata
Title
Tumour-selective transcriptional targeting for breast cancer gene therapy
Author
HC Hurst
Publication date
01-03-2000
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 1/2000
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr186

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