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Published in: BMC Musculoskeletal Disorders 1/2021

Open Access 01-12-2021 | Tuberculosis | Research

Evaluation of patients admitted with musculoskeletal tuberculosis: sixteen years’ experience from a single center in Turkey

Authors: Mikail Ozdemir, H. Gulnihal Ozdemir

Published in: BMC Musculoskeletal Disorders | Issue 1/2021

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Abstract

Background

The aim of our study was to describe musculoskeletal system tuberculosis (TB) as a single-center experience.

Methods

This is a retrospective observational study conducted at a TB Dispensary in the east Mediterranean part of Turkey between 2004 and 2020. The clinical and demographic characteristics including age, gender, involvement location and duration of illness, presenting complaint, local examination findings, treatment outcome were retrieved and analyzed from the case files. Statistical analyses were performed using SPSS Statistics version 17.0 (IBM). The normality of data analysed by using Kolmogorov-Smirnov. The descriptive statistics were reported as mean ± standard deviation, medians, and ranges (min-max).

Results

Overall, 31 patients (3.2 % of all TB cases) with a mean age of 44.2 ± 16.7 years had musculoskeletal tuberculosis. The mean duration of treatment was 12.9 ± 5.5 months. Of the 31 patients, six (19.4 %) had concomitant pulmonary TB. One of the patients was in the pediatrics age group, and two of them were in the geriatric group. The most affected area was the vertebra. The most common complaint of the patients was back pain and seen in 22 patients (70.9 %).

Conclusions

The physicians should be suspicious about the diagnosis of musculoskeletal TB disease. If the diagnosis and treatment are delayed, spinal damage and other consequences might be incurable.
Literature
1.
go back to reference Zaman K. Tuberculosis: a global health problem. J Health Popul Nutri. 2010;28(2):111–3. Zaman K. Tuberculosis: a global health problem. J Health Popul Nutri. 2010;28(2):111–3.
2.
go back to reference Harding E. WHO global progress report on tuberculosis elimination. Lancet Respir Med. 2020;8(1):19.CrossRef Harding E. WHO global progress report on tuberculosis elimination. Lancet Respir Med. 2020;8(1):19.CrossRef
3.
go back to reference Bora Basara B, Soytutan Caglar I, Aygun A, Ozdemir T. Health Statistics Yearbook 2018. Ankara: Republic of Turkey, Ministry of Health, General Directorate of Health Information Systems; 2019. Bora Basara B, Soytutan Caglar I, Aygun A, Ozdemir T. Health Statistics Yearbook 2018. Ankara: Republic of Turkey, Ministry of Health, General Directorate of Health Information Systems; 2019.
4.
go back to reference Ozdemir M. Osmaniye İli Verem Savaş Dispanserliğine Başvuran Hastaların Retrospektif Değerlendirilmesi. Turkish J Fam Med Prim Care. 2020;14(2):252–8.CrossRef Ozdemir M. Osmaniye İli Verem Savaş Dispanserliğine Başvuran Hastaların Retrospektif Değerlendirilmesi. Turkish J Fam Med Prim Care. 2020;14(2):252–8.CrossRef
5.
go back to reference Leonard MK, Blumberg HM. Musculoskeletal Tuberculosis. Microbiology spectrum. 2017;5(2). Leonard MK, Blumberg HM. Musculoskeletal Tuberculosis. Microbiology spectrum. 2017;5(2).
6.
go back to reference Loddenkemper R, Lipman M, Zumla A. Clinical Aspects of Adult Tuberculosis. Cold Spring Harbor Perspect Med. 2015;6(1):a017848.CrossRef Loddenkemper R, Lipman M, Zumla A. Clinical Aspects of Adult Tuberculosis. Cold Spring Harbor Perspect Med. 2015;6(1):a017848.CrossRef
7.
go back to reference Furlow B. Tuberculosis: a review and update. Radiol Tech. 2010;82(1):33–52. Furlow B. Tuberculosis: a review and update. Radiol Tech. 2010;82(1):33–52.
8.
go back to reference Campbell IA, Bah-Sow O. Pulmonary tuberculosis: diagnosis and treatment. BMJ (Clinical research ed). 2006;332(7551):1194–7.CrossRef Campbell IA, Bah-Sow O. Pulmonary tuberculosis: diagnosis and treatment. BMJ (Clinical research ed). 2006;332(7551):1194–7.CrossRef
9.
go back to reference Kandwal P, Jayaswal GV. Management of Tuberculous Infection of the Spine. Asian Spine J. 2016;10(4):792–800.CrossRef Kandwal P, Jayaswal GV. Management of Tuberculous Infection of the Spine. Asian Spine J. 2016;10(4):792–800.CrossRef
10.
go back to reference Hogan JI, Hurtado RM, Nelson SB. Mycobacterial Musculoskeletal Infections. Infect Dis Clin North America. 2017;31(2):369–82.CrossRef Hogan JI, Hurtado RM, Nelson SB. Mycobacterial Musculoskeletal Infections. Infect Dis Clin North America. 2017;31(2):369–82.CrossRef
11.
go back to reference Hogan JI, Hurtado RM, Nelson SB. Mycobacterial Musculoskeletal Infections. Thorac Surg Clin. 2019;29(1):85–94.CrossRef Hogan JI, Hurtado RM, Nelson SB. Mycobacterial Musculoskeletal Infections. Thorac Surg Clin. 2019;29(1):85–94.CrossRef
12.
go back to reference Wagh Y, Reddy R, Gundavda M, Agarwal M, Agashe VM, Bajwa S. Tuberculosis (T.B.) masquerading as tumor. An 8-year study on 25 cases of long bone tuberculosis presenting as tumors. Sicot J. 2020;6:14.CrossRef Wagh Y, Reddy R, Gundavda M, Agarwal M, Agashe VM, Bajwa S. Tuberculosis (T.B.) masquerading as tumor. An 8-year study on 25 cases of long bone tuberculosis presenting as tumors. Sicot J. 2020;6:14.CrossRef
13.
go back to reference Davidson PT, Horowitz I. Skeletal tuberculosis. A review with patient presentations and discussion. Am J Med. 1970;48(1):77–84.CrossRef Davidson PT, Horowitz I. Skeletal tuberculosis. A review with patient presentations and discussion. Am J Med. 1970;48(1):77–84.CrossRef
14.
go back to reference Sharma SK, Mohan A, Kadhiravan T. HIV-TB co-infection: epidemiology, diagnosis & management. Indian J Med Res. 2005;121(4):550–67.PubMed Sharma SK, Mohan A, Kadhiravan T. HIV-TB co-infection: epidemiology, diagnosis & management. Indian J Med Res. 2005;121(4):550–67.PubMed
15.
go back to reference Coskun O, Safaz I, Gul CH, Ozgul A, Eyigun CP. Heterotopic ossification in a patient with tuberculous meningoencephalitis. Intern Med (Tokyo, Japan). 2008;47(24):2195–6.CrossRef Coskun O, Safaz I, Gul CH, Ozgul A, Eyigun CP. Heterotopic ossification in a patient with tuberculous meningoencephalitis. Intern Med (Tokyo, Japan). 2008;47(24):2195–6.CrossRef
16.
go back to reference Lin JN, Lai CH, Chen YH, Lee SS, Tsai SS, Huang CK, et al. Risk factors for extra-pulmonary tuberculosis compared to pulmonary tuberculosis. Int J Tuberc Lung Dis. 2009;13(5):620–5.PubMed Lin JN, Lai CH, Chen YH, Lee SS, Tsai SS, Huang CK, et al. Risk factors for extra-pulmonary tuberculosis compared to pulmonary tuberculosis. Int J Tuberc Lung Dis. 2009;13(5):620–5.PubMed
17.
go back to reference Held MFG, Hoppe S, Laubscher M, Mears S, Dix-Peek S, Zar HJ, et al. Epidemiology of Musculoskeletal Tuberculosis in an Area with High Disease Prevalence. Asian Spine J. 2017;11(3):405–11.CrossRef Held MFG, Hoppe S, Laubscher M, Mears S, Dix-Peek S, Zar HJ, et al. Epidemiology of Musculoskeletal Tuberculosis in an Area with High Disease Prevalence. Asian Spine J. 2017;11(3):405–11.CrossRef
18.
go back to reference Colmenero JD, Jiménez-Mejías ME, Reguera JM, Palomino-Nicás J, Ruiz-Mesa JD, Márquez-Rivas J, et al. Tuberculous vertebral osteomyelitis in the new millennium: still a diagnostic and therapeutic challenge. Eur J Clin Microbiol Infect Dis. 2004;23(6):477–83.CrossRef Colmenero JD, Jiménez-Mejías ME, Reguera JM, Palomino-Nicás J, Ruiz-Mesa JD, Márquez-Rivas J, et al. Tuberculous vertebral osteomyelitis in the new millennium: still a diagnostic and therapeutic challenge. Eur J Clin Microbiol Infect Dis. 2004;23(6):477–83.CrossRef
19.
go back to reference Pazarlı AC, Ekiz T, Abakay MA. Clinical presentation of tuberculosis: a nine-year single-center experience. Eur Res J. 2018;4(3):211–4. Pazarlı AC, Ekiz T, Abakay MA. Clinical presentation of tuberculosis: a nine-year single-center experience. Eur Res J. 2018;4(3):211–4.
20.
go back to reference Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34(5):440–54.CrossRef Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34(5):440–54.CrossRef
21.
go back to reference Shah BA, Splain S. Multifocal osteoarticular tuberculosis. Orthopedics. 2005;28(3):329–32.CrossRef Shah BA, Splain S. Multifocal osteoarticular tuberculosis. Orthopedics. 2005;28(3):329–32.CrossRef
22.
go back to reference Vohra R, Kang HS, Dogra S, Saggar RR, Sharma R. Tuberculous osteomyelitis. J Bone Joint Surg Br. 1997;79(4):562–6.CrossRef Vohra R, Kang HS, Dogra S, Saggar RR, Sharma R. Tuberculous osteomyelitis. J Bone Joint Surg Br. 1997;79(4):562–6.CrossRef
Metadata
Title
Evaluation of patients admitted with musculoskeletal tuberculosis: sixteen years’ experience from a single center in Turkey
Authors
Mikail Ozdemir
H. Gulnihal Ozdemir
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Musculoskeletal Disorders / Issue 1/2021
Electronic ISSN: 1471-2474
DOI
https://doi.org/10.1186/s12891-021-04426-y

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