Skip to main content
Top
Published in: World Journal of Urology 11/2020

01-11-2020 | Tuberculosis | Topic Paper

Urinary tuberculosis: still a challenge

Authors: Ali Mert, Vahit Guzelburc, Selcuk Guven

Published in: World Journal of Urology | Issue 11/2020

Login to get access

Abstract

Background

Urinary tuberculosis (TB) is a challenging disease to cope with, as there has been no noticeable difference in basic diagnostic and therapeutic options in clinical practice over time.

Purpose

The aim of the current review was the critical assessment and evaluation of TB, which remains a major global health problem.

Methods

The available literature regarding TB in the PubMed database was extensively searched.

Results

New interdisciplinary team approaches such as next-generation sequencing are promising for the diagnosis and treatment of the disease. The epidemiology of the disease is changing with globalization and increasing migration events; however, the knowledge here is limited. Despite ongoing destruction, kidney functions need to be preserved as much as possible, and relatively rapid development of minimally invasive techniques relieved the surgeons in this regard. Experience is increasing in minimally invasive techniques that provide better comfort for patients compared to extensive radical surgeries.

Conclusions

Knowing the pathogenesis of urinary TB is essential for understanding the range of clinical manifestations. The onset of the disease is usually insidious. Despite modern TB drugs, reconstructive surgery, and minimally invasive procedures, progression cannot be prevented in some patients, and patient selection is essential, but we still do not have sufficient information and objective parameters to predict progression.
Literature
1.
go back to reference Houben RM, Dodd PJ (2016) The global burden of latent tuberculosis infection: a re-estimation using mathematical modelling. PLoS Med 13:e1002152CrossRef Houben RM, Dodd PJ (2016) The global burden of latent tuberculosis infection: a re-estimation using mathematical modelling. PLoS Med 13:e1002152CrossRef
2.
go back to reference Comstock GW, Livesay VT, Woolpert SF (1974) The prognosis of a positive tuberculin reaction in childhood and adolescence. Am J Epidemiol 99:131–138CrossRef Comstock GW, Livesay VT, Woolpert SF (1974) The prognosis of a positive tuberculin reaction in childhood and adolescence. Am J Epidemiol 99:131–138CrossRef
4.
go back to reference Mantica G, Van der Merwe A, Terrone C, Gallo F, Zarrabi AD, Vlok AL, Ackermann HM, Territo A, Esperto F, Olapade-Olapa EO, Riccardi N, Bongers M, Bonkat G (2019). Awareness of European practitioners toward uncommon tropical diseases: are we prepared to deal with mass migration? Results of an international survey. World J Urol. https://doi.org/10.1007/s00345-019-02957-7. [Epub ahead of print] PubMed PMID: 31538244. Mantica G, Van der Merwe A, Terrone C, Gallo F, Zarrabi AD, Vlok AL, Ackermann HM, Territo A, Esperto F, Olapade-Olapa EO, Riccardi N, Bongers M, Bonkat G (2019). Awareness of European practitioners toward uncommon tropical diseases: are we prepared to deal with mass migration? Results of an international survey. World J Urol. https://​doi.​org/​10.​1007/​s00345-019-02957-7. [Epub ahead of print] PubMed PMID: 31538244.
5.
go back to reference Global health estimates 2016 (2018) Deaths by cause, age, sex, by country, by region, 2000- 2016. Geneva, World Health Organization 2018 Global health estimates 2016 (2018) Deaths by cause, age, sex, by country, by region, 2000- 2016. Geneva, World Health Organization 2018
6.
go back to reference Rieder HL, Snider DE Jr, Cauthen GM (1990) Extrapulmonary tuberculosis in the United States. Am Rev Respir Dis 141(2):347–51CrossRef Rieder HL, Snider DE Jr, Cauthen GM (1990) Extrapulmonary tuberculosis in the United States. Am Rev Respir Dis 141(2):347–51CrossRef
7.
go back to reference Slavin RE, Walsh TJ, Pollack AD (1980) Late generalized tuberculosis: a clinical pathologic analysis and comparison of 100 cases in the preantibiotic and antibiotic eras. Medicine 59:352–366CrossRef Slavin RE, Walsh TJ, Pollack AD (1980) Late generalized tuberculosis: a clinical pathologic analysis and comparison of 100 cases in the preantibiotic and antibiotic eras. Medicine 59:352–366CrossRef
8.
go back to reference Gelb AF, Leffler C, Brewin A, Mascatello V, Lyons HA (1973) Miliary tuberculosis. Am Rev Respir Dis 108:1327–1333 Gelb AF, Leffler C, Brewin A, Mascatello V, Lyons HA (1973) Miliary tuberculosis. Am Rev Respir Dis 108:1327–1333
9.
go back to reference Prout S, Benatar SR (1980) Disseminated tuberculosis. S Afr Med J 1980:835 Prout S, Benatar SR (1980) Disseminated tuberculosis. S Afr Med J 1980:835
10.
go back to reference Figueiredo AA, Lucon AM (2008) Urogenital tuberculosis: update and review of 8961 cases from the world literature. Rev Urol 10:207–217 Figueiredo AA, Lucon AM (2008) Urogenital tuberculosis: update and review of 8961 cases from the world literature. Rev Urol 10:207–217
11.
go back to reference Figueiredo AA, Lucon AM, Junior RF, Srougi M (2008) Epidemiology of urogenital tuberculosis worldwide. Int J Urol 15:827CrossRef Figueiredo AA, Lucon AM, Junior RF, Srougi M (2008) Epidemiology of urogenital tuberculosis worldwide. Int J Urol 15:827CrossRef
12.
go back to reference Yadav S, Singh P, Hemal A, Kumar R (2017) Genital tuberculosis: current status of diagnosis and and management. Transl Androl Urol 6:222–233CrossRef Yadav S, Singh P, Hemal A, Kumar R (2017) Genital tuberculosis: current status of diagnosis and and management. Transl Androl Urol 6:222–233CrossRef
13.
go back to reference Zajaczkowski T (2012) Urinary tuberculosis: historical and basic science review: past and present. Cent Eur J Urol 65:182–187CrossRef Zajaczkowski T (2012) Urinary tuberculosis: historical and basic science review: past and present. Cent Eur J Urol 65:182–187CrossRef
14.
go back to reference Daher EdeF, da Silva GB Jr, Barros EJ (2013) Renal tuberculosis in the modern era. Am J Trop Med Hyg 88:54–64CrossRef Daher EdeF, da Silva GB Jr, Barros EJ (2013) Renal tuberculosis in the modern era. Am J Trop Med Hyg 88:54–64CrossRef
15.
go back to reference R Kasi Visweswaran RK, Pais VM, Dionne-Odom J (2018) Urogenital tuberculosis R Kasi Visweswaran RK, Pais VM, Dionne-Odom J (2018) Urogenital tuberculosis
16.
go back to reference Christensen WI (1974) Genitourinary tuberculosis. Review of 102 cases. Med (Baltim) 53:377–390CrossRef Christensen WI (1974) Genitourinary tuberculosis. Review of 102 cases. Med (Baltim) 53:377–390CrossRef
17.
go back to reference Prout S, Benatar SR (1980) Disseminated tuberculosis. A study of 62 cases. South Afr Med J Suid-Afr Tydskr Vir Geneeskd 58:835–842 Prout S, Benatar SR (1980) Disseminated tuberculosis. A study of 62 cases. South Afr Med J Suid-Afr Tydskr Vir Geneeskd 58:835–842
18.
go back to reference Gelb AF, Leffler C, Brewin A et al (1973) Miliary tuberculosis. Am Rev Respir Dis 108:1327–1333 Gelb AF, Leffler C, Brewin A et al (1973) Miliary tuberculosis. Am Rev Respir Dis 108:1327–1333
19.
go back to reference Mert A, Arslan F, Kuyucu T, Koç EN, Ylmaz M, Turan D, Altn S, Pehlivanoglu F, Sengoz G, Yldz D, Dokmetas I, Komur S, Kurtaran B, Demirdal T, Erdem HA, Sipahi OR, Batirel A, Parlak E, Tekin R, Tunçcan ÖG, Balkan II, Hayran O, Ceylan B (2017) Miliary tuberculosis: epidemiological and clinical analysis of large-case series from moderate to low tuberculosis endemic Country. Med (Baltim) 96:5875CrossRef Mert A, Arslan F, Kuyucu T, Koç EN, Ylmaz M, Turan D, Altn S, Pehlivanoglu F, Sengoz G, Yldz D, Dokmetas I, Komur S, Kurtaran B, Demirdal T, Erdem HA, Sipahi OR, Batirel A, Parlak E, Tekin R, Tunçcan ÖG, Balkan II, Hayran O, Ceylan B (2017) Miliary tuberculosis: epidemiological and clinical analysis of large-case series from moderate to low tuberculosis endemic Country. Med (Baltim) 96:5875CrossRef
20.
go back to reference Merchant S, Bharati A, Merchant N (2013) Tuberculosis of the genitourinary system-Urinary tract tuberculosis: renal tuberculosis-Part I. Indian J Radiol Imaging 23:46–63CrossRef Merchant S, Bharati A, Merchant N (2013) Tuberculosis of the genitourinary system-Urinary tract tuberculosis: renal tuberculosis-Part I. Indian J Radiol Imaging 23:46–63CrossRef
21.
go back to reference Altiparmak MR, Trabulus S, Balkan II, Yalin SF, Denizli N, Aslan G, Doruk HE, Engin A, Tekin R, Birengel S, Cetin BD, Arslan F, Turhan V, Mert A (2015) Urinary tuberculosis: a cohort of 79 adult cases. Ren Fail 37(7):1157–1163CrossRef Altiparmak MR, Trabulus S, Balkan II, Yalin SF, Denizli N, Aslan G, Doruk HE, Engin A, Tekin R, Birengel S, Cetin BD, Arslan F, Turhan V, Mert A (2015) Urinary tuberculosis: a cohort of 79 adult cases. Ren Fail 37(7):1157–1163CrossRef
22.
go back to reference Wang J, Fan S, Xiao J, Liang CZ (2016) Renal tuberculosis tends to be low symptoms: how to improve the diagnosis and treatment of renal tuberculosis. Asian J Androl 18:145–146CrossRef Wang J, Fan S, Xiao J, Liang CZ (2016) Renal tuberculosis tends to be low symptoms: how to improve the diagnosis and treatment of renal tuberculosis. Asian J Androl 18:145–146CrossRef
23.
go back to reference Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL (2017) Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Clin Infect Dis 64:111–115CrossRef Lewinsohn DM, Leonard MK, LoBue PA, Cohn DL, Daley CL, Desmond E, Keane J, Lewinsohn DA, Loeffler AM, Mazurek GH, O'Brien RJ, Pai M, Richeldi L, Salfinger M, Shinnick TM, Sterling TR, Warshauer DM, Woods GL (2017) Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children. Clin Infect Dis 64:111–115CrossRef
24.
go back to reference World Health Organization (2011) Policy framework for implementing new tuberculosis diagnostics. World Health Organization, Geneva World Health Organization (2011) Policy framework for implementing new tuberculosis diagnostics. World Health Organization, Geneva
25.
go back to reference Altez-Fernandez C, Ortiz V, Mirzazadeh M, Zegarra L, Seas C, Ugarte-Gil C (2017) Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis. BMC Infect Dis 17:390CrossRef Altez-Fernandez C, Ortiz V, Mirzazadeh M, Zegarra L, Seas C, Ugarte-Gil C (2017) Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis. BMC Infect Dis 17:390CrossRef
26.
go back to reference Pang Y, Shang Y, Lu J, Liang Q, Dong L, Li Y et al (2017) GeneXpert MTB/RIF assay in the diagnosis of urinary tuberculosis from urine specimens. Sci Rep 7:6181CrossRef Pang Y, Shang Y, Lu J, Liang Q, Dong L, Li Y et al (2017) GeneXpert MTB/RIF assay in the diagnosis of urinary tuberculosis from urine specimens. Sci Rep 7:6181CrossRef
27.
go back to reference Atherton RR, Cresswell FV, Ellis J, Skipper C, Tadeo KK, Mugumya G, Wadda V, Meya DB, Boulware DR (2018) Detection of Mycobacterium tuberculosis in urine by Xpert MTB/RIF ultra: a useful adjunctive diagnostic tool in HIV-associated tuberculosis. Int J Infect Dis 75:92–94CrossRef Atherton RR, Cresswell FV, Ellis J, Skipper C, Tadeo KK, Mugumya G, Wadda V, Meya DB, Boulware DR (2018) Detection of Mycobacterium tuberculosis in urine by Xpert MTB/RIF ultra: a useful adjunctive diagnostic tool in HIV-associated tuberculosis. Int J Infect Dis 75:92–94CrossRef
28.
go back to reference Papaventsis D, Casali N, Kontsevaya I, Drobniewski F, Cirillo DM, Nikolayevskyy V (2017) Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review. Clin Microbiol Infect 23:61–68CrossRef Papaventsis D, Casali N, Kontsevaya I, Drobniewski F, Cirillo DM, Nikolayevskyy V (2017) Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review. Clin Microbiol Infect 23:61–68CrossRef
29.
go back to reference Votintseva AA, Bradley P, Pankhurst L, Del Ojo EC, Loose M, Nilgiriwala K, Chatterjee A, Smith EG, Sanderson N, Walker TM, Morgan MR, Wyllie DH, Walker AS, Peto TEA, Crook DW, Iqbal Z (2017) Same-day diagnostic and surveillance data for tuberculosis via whole-genome sequencing of direct respiratory samples. J Clin Microbiol 55:1285–1298CrossRef Votintseva AA, Bradley P, Pankhurst L, Del Ojo EC, Loose M, Nilgiriwala K, Chatterjee A, Smith EG, Sanderson N, Walker TM, Morgan MR, Wyllie DH, Walker AS, Peto TEA, Crook DW, Iqbal Z (2017) Same-day diagnostic and surveillance data for tuberculosis via whole-genome sequencing of direct respiratory samples. J Clin Microbiol 55:1285–1298CrossRef
30.
go back to reference Lattimer JK, Wechsler H, Ehrlich RM, Fukushima K (1969) Current treatment for renal tuberculosis. J Ural 102:2–6CrossRef Lattimer JK, Wechsler H, Ehrlich RM, Fukushima K (1969) Current treatment for renal tuberculosis. J Ural 102:2–6CrossRef
31.
go back to reference Blumberg HM, Burman WJ, Chaisson RE et al (2003) American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am J Respir Crit Care Med 167:603–662CrossRef Blumberg HM, Burman WJ, Chaisson RE et al (2003) American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am J Respir Crit Care Med 167:603–662CrossRef
32.
go back to reference Saukkonen JJ et al (2006) An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med 174:935–952CrossRef Saukkonen JJ et al (2006) An official ATS statement: hepatotoxicity of antituberculosis therapy. Am J Respir Crit Care Med 174:935–952CrossRef
34.
go back to reference Wong SH, Lau WY (1980) The surgical management of non-functioning tuberculous kidneys. J Urol 124(2):187–191CrossRef Wong SH, Lau WY (1980) The surgical management of non-functioning tuberculous kidneys. J Urol 124(2):187–191CrossRef
35.
go back to reference Kulchavenya E (2019) Surgery. In: Urogenital Tuberculosis: Epidemiology, Diagnosis, Therapy Springer Cham Heidelberg New York Dordrecht London, pp 109–110 Kulchavenya E (2019) Surgery. In: Urogenital Tuberculosis: Epidemiology, Diagnosis, Therapy Springer Cham Heidelberg New York Dordrecht London, pp 109–110
37.
go back to reference Zuban’ ON, Iagafarova RK, Vinogradova TI (2006) Diagnosis and treatment of urinary bladder dysfunctions in patients with nephrotuberculosis. Urologiia 5:37–40, 45 (Russian) Zuban’ ON, Iagafarova RK, Vinogradova TI (2006) Diagnosis and treatment of urinary bladder dysfunctions in patients with nephrotuberculosis. Urologiia 5:37–40, 45 (Russian)
38.
go back to reference Flechner SM, Gow JG (1980) Role of nephrectomy in the treatment of non-functioning or very poorly functioning unilateral tuberculous kidney. Urol J 123(6):822–825CrossRef Flechner SM, Gow JG (1980) Role of nephrectomy in the treatment of non-functioning or very poorly functioning unilateral tuberculous kidney. Urol J 123(6):822–825CrossRef
39.
go back to reference Singh V, Sinha RJ, Sankhwar SN, Sinha SM (2011) Reconstructive surgery for tuberculous contracted bladder: experience of a center in northern India. Int Urol Nephrol 43(2):423–430CrossRef Singh V, Sinha RJ, Sankhwar SN, Sinha SM (2011) Reconstructive surgery for tuberculous contracted bladder: experience of a center in northern India. Int Urol Nephrol 43(2):423–430CrossRef
40.
go back to reference Modi PR, Rizvi SJ (2008) Retroperitoneoscopic nephrectomy for nephrocolonic fistula due to tuberculous nonfunctioning kidney. J Laparoendosc Adv Surg Tech A 18(6):841–843CrossRef Modi PR, Rizvi SJ (2008) Retroperitoneoscopic nephrectomy for nephrocolonic fistula due to tuberculous nonfunctioning kidney. J Laparoendosc Adv Surg Tech A 18(6):841–843CrossRef
41.
go back to reference Han WK, Park YH, Jeon HG (2010) The feasibility of laparoendoscopic single-site nephrectomy:initial experience using home-made single-port device. Urology 76(4):862–865CrossRef Han WK, Park YH, Jeon HG (2010) The feasibility of laparoendoscopic single-site nephrectomy:initial experience using home-made single-port device. Urology 76(4):862–865CrossRef
42.
go back to reference Hemal AK, Gupta NP (2000) Kumar R Comparison of retroperitoneoscopic nephrectomy with open surgery for tuberculous nonfunctioning kidneys. J Urol 164(1):32–35CrossRef Hemal AK, Gupta NP (2000) Kumar R Comparison of retroperitoneoscopic nephrectomy with open surgery for tuberculous nonfunctioning kidneys. J Urol 164(1):32–35CrossRef
43.
go back to reference Suárez-Grau JM, Bellido-Luque JA, Pastrana-Mejía A, Gómez-Menchero J, García-Moreno JL, Durán-Ferreras I (2012) Guadalajara-Jurado JF Laparoscopic surgery of an enterovesical fistula of tuberculous origin (terminal ileum and sigmoid colon). Rev Esp Enferm Dig 104(7):391–392CrossRef Suárez-Grau JM, Bellido-Luque JA, Pastrana-Mejía A, Gómez-Menchero J, García-Moreno JL, Durán-Ferreras I (2012) Guadalajara-Jurado JF Laparoscopic surgery of an enterovesical fistula of tuberculous origin (terminal ileum and sigmoid colon). Rev Esp Enferm Dig 104(7):391–392CrossRef
44.
go back to reference Gupta NP, Agrawal AK (1997) Sood S Tubercular pyelonephritic nonfunctioning kidney–another relative contraindication for laparoscopic nephrectomy: a case report. J Laparoendosc Adv Surg Tech A 7(2):131–134CrossRef Gupta NP, Agrawal AK (1997) Sood S Tubercular pyelonephritic nonfunctioning kidney–another relative contraindication for laparoscopic nephrectomy: a case report. J Laparoendosc Adv Surg Tech A 7(2):131–134CrossRef
45.
go back to reference Ramanathan R, Kumar A, Kapoor R, Bhandari M (1998) Relief of urinary tract obstruction in tuberculosis to improve renal function. Analysis of predictive factors. Br J Urol 81(2):199–205CrossRef Ramanathan R, Kumar A, Kapoor R, Bhandari M (1998) Relief of urinary tract obstruction in tuberculosis to improve renal function. Analysis of predictive factors. Br J Urol 81(2):199–205CrossRef
46.
go back to reference Li X, Liu ZJ, Liu JW, Cai M, Chen S, Yu T, Tang YZ, Liu YB, Wang Q (2019 ) A Clinical comparative analysis of retroperitoneal laparoscopic tuberculous nephrectomy and open tuberculous nephrectomy. J Laparoendosc Adv Surg Tech A 29(7):909–913. https://doi.org/10.1089/lap.2018.0808Epub 2019 Mar 30 PubMed PMID: 30932738CrossRef Li X, Liu ZJ, Liu JW, Cai M, Chen S, Yu T, Tang YZ, Liu YB, Wang Q (2019 ) A Clinical comparative analysis of retroperitoneal laparoscopic tuberculous nephrectomy and open tuberculous nephrectomy. J Laparoendosc Adv Surg Tech A 29(7):909–913. https://​doi.​org/​10.​1089/​lap.​2018.​0808Epub 2019 Mar 30 PubMed PMID: 30932738CrossRef
49.
Metadata
Title
Urinary tuberculosis: still a challenge
Authors
Ali Mert
Vahit Guzelburc
Selcuk Guven
Publication date
01-11-2020
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 11/2020
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-020-03146-7

Other articles of this Issue 11/2020

World Journal of Urology 11/2020 Go to the issue