Skip to main content
Top
Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Tuberculosis active case finding: uptake and diagnostic yield among minibus drivers in urban South Africa

Authors: Tonderai Mabuto, Ephraim Zwane, Violet Chihota, Gillian Gresak, Salome Charalambous, Gavin J Churchyard, Christopher J Hoffmann

Published in: BMC Public Health | Issue 1/2015

Login to get access

Abstract

Background

Tuberculosis (TB) active case finding is a part of TB control in areas of higher TB prevalence. Congested public transportation settings may be areas of increased TB transmission. We evaluated the uptake and diagnostic yield of an active TB screening program among minibus drivers in a large public transportation facility in Johannesburg, South Africa.

Methods

Over an eight month period, we intensively recruited minibus drivers for TB screening with a goal of 80% uptake among the estimated 2000 drivers. All participants were screened for TB symptoms, offered HIV testing, and had sputum collected for smear microscopy and liquid culture.

Results

686 drivers were screened for TB, representing an uptake of only 34% of all drivers (43% of the target screening). Ten drivers (1.5%) were culture positive for TB, nine of whom were sputum smear microscopy negative. Factors associated with previously undiagnosed TB included a history of incarceration (odds ratio [OR] 5.5, 95% confidence interval: 1.1, 27.3) and HIV positivity (OR 5.3, 95% confidence interval: 1.1, 26.3).

Conclusions

We identified undiagnosed pulmonary TB cases among drivers but at a level that may be insufficient to justify systematic case finding in this population considering the poor uptake.
Literature
1.
go back to reference WHO. Global Tuberculosis Report 2014. Geneva, Switzerland: World Health Organization; 2014. WHO. Global Tuberculosis Report 2014. Geneva, Switzerland: World Health Organization; 2014.
2.
go back to reference WHO. Global tuberculosis report 2013. Geneva, Switzerland: World Health Organization; 2013. WHO. Global tuberculosis report 2013. Geneva, Switzerland: World Health Organization; 2013.
3.
go back to reference WHO. Systematic screening for active tuberculosis: principles and recommendations. Geneva, Switzerland: World Health Organization; 2013. WHO. Systematic screening for active tuberculosis: principles and recommendations. Geneva, Switzerland: World Health Organization; 2013.
4.
go back to reference Dowdy DW, Golub JE, Chaisson RE, Saraceni V. Heterogeneity in tuberculosis transmission and the role of geographic hotspots in propagating epidemics. Proc Natl Acad Sci U S A. 2012;109(24):9557–62. 10.1073/pnas.1203517109.CrossRef Dowdy DW, Golub JE, Chaisson RE, Saraceni V. Heterogeneity in tuberculosis transmission and the role of geographic hotspots in propagating epidemics. Proc Natl Acad Sci U S A. 2012;109(24):9557–62. 10.1073/pnas.1203517109.CrossRef
5.
go back to reference Dowdy DW, Azman AS, Kendall EA, Mathema B. Transforming the fight against tuberculosis: targeting catalysts of transmission. Clin Infect Dis. 2014;59(8):1123–9. 10.1093/cid/ciu506.CrossRef Dowdy DW, Azman AS, Kendall EA, Mathema B. Transforming the fight against tuberculosis: targeting catalysts of transmission. Clin Infect Dis. 2014;59(8):1123–9. 10.1093/cid/ciu506.CrossRef
6.
go back to reference Haq GS, D. Transport and environment in sub-Saharan Africa. 2012 Haq GS, D. Transport and environment in sub-Saharan Africa. 2012
7.
go back to reference Morrow KM. HIV, STD, and hepatitis risk behaviors of young men before and after incarceration. AIDS Care. 2009;21(2):235–43. doi:10.1080/09540120802017586.CrossRef Morrow KM. HIV, STD, and hepatitis risk behaviors of young men before and after incarceration. AIDS Care. 2009;21(2):235–43. doi:10.1080/09540120802017586.CrossRef
8.
go back to reference Luke R, Heyns G. Public transport policy and performance: the results of a South African opinion poll. J Transp Supply Chain Manag. 2013;7:8–12. Luke R, Heyns G. Public transport policy and performance: the results of a South African opinion poll. J Transp Supply Chain Manag. 2013;7:8–12.
9.
go back to reference Horna-Campos OJ, Consiglio E, Sanchez-Perez HJ, Navarro A, Cayla JA, Martin-Mateo M. Pulmonary tuberculosis infection among workers in the informal public transport sector in Lima, Peru. Occup Environ Med. 2011;68(2):163–5. 10.1136/oem.2009.051128.CrossRef Horna-Campos OJ, Consiglio E, Sanchez-Perez HJ, Navarro A, Cayla JA, Martin-Mateo M. Pulmonary tuberculosis infection among workers in the informal public transport sector in Lima, Peru. Occup Environ Med. 2011;68(2):163–5. 10.1136/oem.2009.051128.CrossRef
10.
go back to reference Horna-Campos OJ, Bedoya-Lama A, Romero-Sandoval NC, Martin-Mateo M. Risk of tuberculosis in public transport sector workers, Lima, Peru. Int J Tuberc Lung Dis Off J Int Union Tuberc Lung Dis. 2010;14(6):714–9. Horna-Campos OJ, Bedoya-Lama A, Romero-Sandoval NC, Martin-Mateo M. Risk of tuberculosis in public transport sector workers, Lima, Peru. Int J Tuberc Lung Dis Off J Int Union Tuberc Lung Dis. 2010;14(6):714–9.
11.
go back to reference Horna-Campos OJ, Sanchez-Perez HJ, Sanchez I, Bedoya A, Martin M. Public transportation and pulmonary tuberculosis, Lima, Peru. Emerg Infect Dis. 2007;13(10):1491–3. 10.3201/eid1310.060793.CrossRef Horna-Campos OJ, Sanchez-Perez HJ, Sanchez I, Bedoya A, Martin M. Public transportation and pulmonary tuberculosis, Lima, Peru. Emerg Infect Dis. 2007;13(10):1491–3. 10.3201/eid1310.060793.CrossRef
12.
go back to reference MTC. Mid-year report 2011/2012. Johannesburg, South Africa: Metro Trading Company (SOC) Limited2012. MTC. Mid-year report 2011/2012. Johannesburg, South Africa: Metro Trading Company (SOC) Limited2012.
13.
go back to reference Getahun H, Kittikraisak W, Heilig C, Corbett EL, Ayles H, Cain K, et al. Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings. PLoSMed. 2011;8(1):e1000391. Getahun H, Kittikraisak W, Heilig C, Corbett EL, Ayles H, Cain K, et al. Development of a standardized screening rule for tuberculosis in people living with HIV in resource-constrained settings. PLoSMed. 2011;8(1):e1000391.
14.
go back to reference Amod AA-E B, Berg G. The 2012 SEMDSA guidelines for the management of type 2 diabetes. JEMDSA. 2012;17:S1–95. Amod AA-E B, Berg G. The 2012 SEMDSA guidelines for the management of type 2 diabetes. JEMDSA. 2012;17:S1–95.
15.
go back to reference Kranzer K, Lawn SD, Meyer-Rath G, Vassall A, Raditlhalo E, Govindasamy D, et al. Feasibility, yield, and cost of active tuberculosis case finding linked to a mobile HIV service in Cape Town, South Africa: a cross-sectional study. PLoS Med. 2012;9(8):e1001281. 10.1371/journal.pmed.1001281.CrossRef Kranzer K, Lawn SD, Meyer-Rath G, Vassall A, Raditlhalo E, Govindasamy D, et al. Feasibility, yield, and cost of active tuberculosis case finding linked to a mobile HIV service in Cape Town, South Africa: a cross-sectional study. PLoS Med. 2012;9(8):e1001281. 10.1371/journal.pmed.1001281.CrossRef
16.
go back to reference Ayles H, Muyoyeta M, Du TE, Schaap A, Floyd S, Simwinga M, et al. Effect of household and community interventions on the burden of tuberculosis in southern Africa: the ZAMSTAR community-randomised trial. Lancet. 2013;382(9899):1183–94. doi:10.1016/S0140-6736(13)61131-9.CrossRef Ayles H, Muyoyeta M, Du TE, Schaap A, Floyd S, Simwinga M, et al. Effect of household and community interventions on the burden of tuberculosis in southern Africa: the ZAMSTAR community-randomised trial. Lancet. 2013;382(9899):1183–94. doi:10.1016/S0140-6736(13)61131-9.CrossRef
17.
go back to reference Andrews JR, Morrow C, Wood R. Modeling the role of public transportation in sustaining tuberculosis transmission in South Africa. Am J Epidemiol. 2013;177(6):556–61. 10.1093/aje/kws331.CrossRef Andrews JR, Morrow C, Wood R. Modeling the role of public transportation in sustaining tuberculosis transmission in South Africa. Am J Epidemiol. 2013;177(6):556–61. 10.1093/aje/kws331.CrossRef
18.
go back to reference Maartens G, Wilkinson RJ. Tuberculosis. Lancet. 2007;370(9604):2030–43. 10.1016/S0140-6736(07)61262-8.CrossRef Maartens G, Wilkinson RJ. Tuberculosis. Lancet. 2007;370(9604):2030–43. 10.1016/S0140-6736(07)61262-8.CrossRef
19.
go back to reference Coninx R, Maher D, Reyes H, Grzemska M. Tuberculosis in prisons in countries with high prevalence. BMJ. 2000;320(7232):440–2.CrossRef Coninx R, Maher D, Reyes H, Grzemska M. Tuberculosis in prisons in countries with high prevalence. BMJ. 2000;320(7232):440–2.CrossRef
Metadata
Title
Tuberculosis active case finding: uptake and diagnostic yield among minibus drivers in urban South Africa
Authors
Tonderai Mabuto
Ephraim Zwane
Violet Chihota
Gillian Gresak
Salome Charalambous
Gavin J Churchyard
Christopher J Hoffmann
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-1592-x

Other articles of this Issue 1/2015

BMC Public Health 1/2015 Go to the issue