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Strahlentherapie und Onkologie
Published in: Strahlentherapie und Onkologie 2/2012

01-02-2012 | Literatur kommentiert

Trotz geringer dosislimitierender Toxizität ist Vorsicht bei der extrem hypofraktionierten Dosiseskalation mithilfe Körperstereotaxie (SBRT) bei frühen Prostatakarzinomen mit niedrigem oder intermediärem Risikoprofil geboten

Author: M. Bremer

Published in: Strahlentherapie und Onkologie | Issue 2/2012

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Boike TP, Lotan Y, Cho LC et al (2011) Phase I dose-ecalation study of stereotactic body radiation therapy for low- and intermediate-risk prostate cancer. J Clin Oncol 29:2020–2026 …
Literature
1.
Brenner DJ, Martinez AA, Edmundson GK et al (2002) Direct evidence that prostate tumors show high sensitivity to fractionation (low alpha/beta ratio), similar to late-responding normal tissue. Int J Radiat Oncol Biol Phys 52:6–13PubMedCrossRef
2.
Martinez AA, Gonzalez J, Ye H et al (2011) Dose escalation improves cancer-related events at 10 years for intermediate- and high-risk prostate cancer patients treated with hypofractionated high-dose-rate boost and external beam radiotherapy. Int J Radiat Oncol Biol Phys 79:363–370PubMedCrossRef
3.
Martinez AA, Pataki I, Edmundson G et al (2001) Phase II prospective study of the use of conformal high-dose-rate brachytherapy as monotherapy for the treatment of favorable stage prostate cancer: a feasibility report. Int J Radiat Oncol Biol Phys 49:61–69PubMedCrossRef
4.
Nickers P, Hermesse J, Deneufbourg JM et al (2010) Which α/β ratio and half-time of repair are useful for predicting outcomes in prostate cancer? Radiother Oncol 97:462–466PubMedCrossRef
Metadata
Title
Trotz geringer dosislimitierender Toxizität ist Vorsicht bei der extrem hypofraktionierten Dosiseskalation mithilfe Körperstereotaxie (SBRT) bei frühen Prostatakarzinomen mit niedrigem oder intermediärem Risikoprofil geboten
Author
M. Bremer
Publication date
01-02-2012
Publisher
Springer Berlin Heidelberg
Published in
Strahlentherapie und Onkologie / Issue 2/2012
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-011-0033-8

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