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AIDS and Behavior
Published in: AIDS and Behavior 3/2016

01-03-2016 | Original Paper

Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV

Authors: William C. Becker, Kirsha Gordon, E. Jennifer Edelman, Robert D. Kerns, Stephen Crystal, James D. Dziura, Lynn E. Fiellin, Adam J. Gordon, Joseph L. Goulet, Amy C. Justice, David A. Fiellin

Published in: AIDS and Behavior | Issue 3/2016

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Abstract

Harms of opioid analgesics, especially high-dose therapy among individuals with comorbidities and older age, are increasingly recognized. However, trends in opioid receipt among HIV-infected patients are not well characterized. We examined trends, from 1999 to 2010, in any and high-dose (≥120 mg/day) opioid receipt among patients with and without HIV, by age strata, controlling for demographic and clinical correlates. Of 127,216 patients, 64 % received at least one opioid prescription. Opioid receipt increased substantially among HIV-infected and uninfected patients over the study; high-dose therapy was more prevalent among HIV-infected patients. Trends in high-dose receipt stratified by three age groups revealed an increasing trend in each age strata, higher among HIV-infected patients. Correlates of any opioid receipt included HIV, PTSD and major depression. Correlates of high-dose receipt included HIV, PTSD, major depression and drug use disorders. These findings suggest a need for appropriate balance of risks and benefits, especially as these populations age.
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Metadata
Title
Trends in Any and High-Dose Opioid Analgesic Receipt Among Aging Patients With and Without HIV
Authors
William C. Becker
Kirsha Gordon
E. Jennifer Edelman
Robert D. Kerns
Stephen Crystal
James D. Dziura
Lynn E. Fiellin
Adam J. Gordon
Joseph L. Goulet
Amy C. Justice
David A. Fiellin
Publication date
01-03-2016
Publisher
Springer US
Published in
AIDS and Behavior / Issue 3/2016
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-015-1197-5

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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