Skip to main content
Top
Published in: CardioVascular and Interventional Radiology 8/2017

01-08-2017 | Clinical Investigation

Treatment Evaluation of Flow-Limiting Stenoses of the Superficial Femoral and Popliteal Artery by Parametric Color-Coding Analysis of Digital Subtraction Angiography Series

Authors: Michael Kostrzewa, Kerim Kara, Lothar Pilz, Hannelore Mueller-Muertz, Nils Rathmann, Stefan O. Schoenberg, Steffen J. Diehl

Published in: CardioVascular and Interventional Radiology | Issue 8/2017

Login to get access

Abstract

Purpose

To evaluate the hemodynamic effect of percutaneous transluminal intervention (PTI) on stenosis of the superficial femoral (SFA) and popliteal arteries (PA) using time–density curves (TDCs) derived from digital subtraction angiography (DSA) series in correlation with ultrasound peak systolic velocity ratio (PSVR) and ankle brachial index (ABI).

Materials and Methods

DSA series of SFA or PA of patients with symptomatic peripheral arterial occlusive disease was obtained with a flat-panel angiography system with intention-to-treat. In DSA series acquired before and after PTI, TDCs were analyzed proximal and distal of each stenosis using parametric color coding (PCC). For correlation, ABI and PSVR measurements pre- and post-PTI were recorded for all patients.

Results

In total, 25 stenoses of the SFA or PA were treated by PTI in 22 patients (17 male, 5 female, mean age 68 years). After treatment, peak-to-peak (PTP) times between TDCs proximal and distal to the treated vessel segment decreased statistically significantly (p = 0.01) on average from PTP = 1.9 ± 1.7 s to mean PTP = 1 ± 1 s. ABI and PSVR also changed statistically significantly after treatment (pretreatment ABI = 0.7 ± 0.2, PSVR = 4.2 ± 1.9; post-ABI = 0.9 ± 0.2, PSVR = 1.3 ± 0.4, both p < 0.05). Correlation parameters did not show a strong correlation between change in TDC and clinical parameters ABI and PSVR.

Conclusion

Using PCC for analyzing contrast medium dynamics in DSA series is clinically useful for evaluating stenoses of the SFA and PA and for immediate treatment control after PTA.

Level of Evidence

Case series, IV
Literature
2.
go back to reference Reinecke H, Unrath M, Freisinger E, Bunzemeier H, Meyborg M, Luders F, et al. Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence. Eur Heart J. 2015;36(15):932–8. doi:10.1093/eurheartj/ehv006.CrossRefPubMed Reinecke H, Unrath M, Freisinger E, Bunzemeier H, Meyborg M, Luders F, et al. Peripheral arterial disease and critical limb ischaemia: still poor outcomes and lack of guideline adherence. Eur Heart J. 2015;36(15):932–8. doi:10.​1093/​eurheartj/​ehv006.CrossRefPubMed
3.
go back to reference Hansmann J, Michaely HJ, Morelli JN, Diehl SJ, Meyer M, Schoenberg SO, et al. Impact of time-resolved MRA on diagnostic accuracy in patients with symptomatic peripheral artery disease of the calf station. Am J Roentgenol. 2013;201(6):1368–75. doi:10.2214/AJR.13.10584.CrossRef Hansmann J, Michaely HJ, Morelli JN, Diehl SJ, Meyer M, Schoenberg SO, et al. Impact of time-resolved MRA on diagnostic accuracy in patients with symptomatic peripheral artery disease of the calf station. Am J Roentgenol. 2013;201(6):1368–75. doi:10.​2214/​AJR.​13.​10584.CrossRef
4.
go back to reference Shang EK, Nathan DP, Fairman RM, Bavaria JE, Gorman RC, Gorman JH III, et al. Use of computational fluid dynamics studies in predicting aneurysmal degeneration of acute type B aortic dissections. J Vasc Surg. 2015. doi:10.1016/j.jvs.2015.02.048. Shang EK, Nathan DP, Fairman RM, Bavaria JE, Gorman RC, Gorman JH III, et al. Use of computational fluid dynamics studies in predicting aneurysmal degeneration of acute type B aortic dissections. J Vasc Surg. 2015. doi:10.​1016/​j.​jvs.​2015.​02.​048.
5.
go back to reference Decrinis M, Doder S, Stark G, Pilger E. A prospective evaluation of sensitivity and specificity of the ankle/brachial index in the follow-up of superficial femoral artery occlusions treated by angioplasty. Clin Investig. 1994;72(8):592–7.CrossRefPubMed Decrinis M, Doder S, Stark G, Pilger E. A prospective evaluation of sensitivity and specificity of the ankle/brachial index in the follow-up of superficial femoral artery occlusions treated by angioplasty. Clin Investig. 1994;72(8):592–7.CrossRefPubMed
7.
go back to reference Golitz P, Struffert T, Lucking H, Rosch J, Knossalla F, Ganslandt O, et al. Parametric color coding of digital subtraction angiography in the evaluation of carotid cavernous fistulas. Clin Neuroradiol. 2013;23(2):113–20. doi:10.1007/s00062-012-0184-8.CrossRefPubMed Golitz P, Struffert T, Lucking H, Rosch J, Knossalla F, Ganslandt O, et al. Parametric color coding of digital subtraction angiography in the evaluation of carotid cavernous fistulas. Clin Neuroradiol. 2013;23(2):113–20. doi:10.​1007/​s00062-012-0184-8.CrossRefPubMed
8.
go back to reference Golitz P, Struffert T, Rosch J, Ganslandt O, Knossalla F, Doerfler A. Cerebral aneurysm treatment using flow-diverting stents: in vivo visualization of flow alterations by parametric colour coding to predict aneurysmal occlusion: preliminary results. Eur Radiol. 2015;25(2):428–35. doi:10.1007/s00330-014-3411-7.CrossRefPubMed Golitz P, Struffert T, Rosch J, Ganslandt O, Knossalla F, Doerfler A. Cerebral aneurysm treatment using flow-diverting stents: in vivo visualization of flow alterations by parametric colour coding to predict aneurysmal occlusion: preliminary results. Eur Radiol. 2015;25(2):428–35. doi:10.​1007/​s00330-014-3411-7.CrossRefPubMed
10.
11.
go back to reference Strother CM, Bender F, Deuerling-Zheng Y, Royalty K, Pulfer KA, Baumgart J, et al. Parametric color coding of digital subtraction angiography. AJNR Am J Neuroradiol. 2010;31(5):919–24. doi:10.3174/ajnr.A2020.CrossRefPubMed Strother CM, Bender F, Deuerling-Zheng Y, Royalty K, Pulfer KA, Baumgart J, et al. Parametric color coding of digital subtraction angiography. AJNR Am J Neuroradiol. 2010;31(5):919–24. doi:10.​3174/​ajnr.​A2020.CrossRefPubMed
12.
go back to reference Lin CJ, Yu M, Hung SC, Teng MM, Guo WY, Chang FC, et al. In-room assessment of cerebral blood volume for guidance during intra-arterial thrombolytic therapy. Interv neuroradiol. 2012;18(4):463–8.CrossRefPubMedPubMedCentral Lin CJ, Yu M, Hung SC, Teng MM, Guo WY, Chang FC, et al. In-room assessment of cerebral blood volume for guidance during intra-arterial thrombolytic therapy. Interv neuroradiol. 2012;18(4):463–8.CrossRefPubMedPubMedCentral
14.
go back to reference Lou WS, Su HB, Huang KY, He X, Chen L, Chen GP, et al. Evaluation of distal hemodynamic changes of lower extremity after endovascular treatment: correlation between measurements of color-coded quantitative digital subtraction angiography and ankle-brachial index. JVIR. 2016. doi:10.1016/j.jvir.2016.02.011.PubMed Lou WS, Su HB, Huang KY, He X, Chen L, Chen GP, et al. Evaluation of distal hemodynamic changes of lower extremity after endovascular treatment: correlation between measurements of color-coded quantitative digital subtraction angiography and ankle-brachial index. JVIR. 2016. doi:10.​1016/​j.​jvir.​2016.​02.​011.PubMed
16.
go back to reference Shpilfoygel SD, Close RA, Valentino DJ, Duckwiler GR. X-ray videodensitometric methods for blood flow and {Shpilfoygel, 2000#164}velocity measurement: a critical review of literature. Med Phys. 2000;27(9):2008–23.CrossRefPubMed Shpilfoygel SD, Close RA, Valentino DJ, Duckwiler GR. X-ray videodensitometric methods for blood flow and {Shpilfoygel, 2000#164}velocity measurement: a critical review of literature. Med Phys. 2000;27(9):2008–23.CrossRefPubMed
17.
go back to reference Cole BL, Maddocks JD, Sharpe K. Visual search and the conspicuity of coloured targets for colour vision normal and colour vision deficient observers. Clin Exper Optom. 2004;87(4–5):294–304.CrossRef Cole BL, Maddocks JD, Sharpe K. Visual search and the conspicuity of coloured targets for colour vision normal and colour vision deficient observers. Clin Exper Optom. 2004;87(4–5):294–304.CrossRef
18.
20.
Metadata
Title
Treatment Evaluation of Flow-Limiting Stenoses of the Superficial Femoral and Popliteal Artery by Parametric Color-Coding Analysis of Digital Subtraction Angiography Series
Authors
Michael Kostrzewa
Kerim Kara
Lothar Pilz
Hannelore Mueller-Muertz
Nils Rathmann
Stefan O. Schoenberg
Steffen J. Diehl
Publication date
01-08-2017
Publisher
Springer US
Published in
CardioVascular and Interventional Radiology / Issue 8/2017
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-017-1670-9

Other articles of this Issue 8/2017

CardioVascular and Interventional Radiology 8/2017 Go to the issue