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Open Access 01-12-2024 | Trabeculectomy | Original Paper

A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy

Authors: Caroline Gietzelt, Lilo Koenig, Werner Adler, Friederike Schaub, Ludwig M. Heindl, Claus Cursiefen, Thomas S. Dietlein, Philip Enders

Published in: International Ophthalmology | Issue 1/2024

Abstract

Purpose

To assess and compare the risk for development of cystoid macula edema (CME) after glaucoma drainage device (GDD) implantation versus conventional trabeculectomy with mitomycin (trab) for glaucoma.

Methods

Retrospective review of consecutive patients receiving trab or GDD implantation between 2016 and 2018. Inclusion criteria were availability of pre- and postoperative spectral domain optical coherence tomography (SD-OCT) of the macula. SD-OCT images were evaluated for presence of CME qualitatively, central subfield thickness (CST) and macular volume (MV).

Results

73 eyes could be included, 42 received trab and 31 GDD surgery. Eyes receiving trab on average had 0.8 ± 0.8 previous intraocular operations, while eyes with GDD implantation had 3.1 ± 1.9 (p < 0.001). Occurrence of postoperative CME was significantly more frequent after GDD implantation (6 out of 31 (19.4%)) than after trab (2 out of 42 eyes = 4.8%), (p = 0.049). Mean preoperative CST as well as MV was comparable in both groups (CST before trab: 282.7 ± 23.0 µm, CST before GDD 284.2 ± 27.3 µm, p = 0.287; MV before trab: 7.8 ± 1.1 mm³, MV before GDD: 8.0 ± 0.8mm³, p = 0.305). Mean postoperative CST and MV were significantly higher after GDD (CST 338.5 ± 129.3 µm, MV 8.8 ± 2.6 mm³) than after trabeculectomy (CST 290.6 ± 60.2 µm, p = 0.038; MV 7.8 ± 1.2mm³, p = 0.039).

Conclusions

In real-life conditions, GDD surgery seems to be associated with a higher risk to develop CME when compared to conventional trabeculectomy. This information may be helpful for glaucoma surgeons to advise the patients on postoperative risks of surgery.

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Title: A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy
Authors: Caroline Gietzelt
Lilo Koenig
Werner Adler
Friederike Schaub
Ludwig M. Heindl
Claus Cursiefen
Thomas S. Dietlein
Philip Enders
Publication date: 01-12-2024
Publisher: Springer Netherlands
Keywords: Trabeculectomy
Glaucoma
Edema
Published in: International Ophthalmology / Issue 1/2024
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-024-03068-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A comparative study of cystoid macula edema following glaucoma drainage device surgery versus trabeculectomy

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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