Published in:
01-08-2016 | Images in Nephrology
Toxic epidermal necrolysis due to cyclophosphamide
Published in: Clinical and Experimental Nephrology | Issue 4/2016
Login to get accessExcerpt
A 63-year-old-male was admitted with rapidly progressive glomerulonephritis (RPGN) and diagnosed as microscopic polyangiitis. Pulse methylprednisolone (MP) (total 3 g) and intravenous cyclophosphamide (CYC) 500 mg were started. After 2 weeks, diffuse erythema, mucocutaneous tenderness and blisters developed and within a week epidermal detachments were apparent (Fig. 1). Involvement of the mucosa occurred with oral aphthous ulcers and conjunctivitis.
Fig. 1
The clinical skin manifestation of TEN
× ![]()
…