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Published in: Lasers in Medical Science 6/2016

01-08-2016 | Original Article

Towards the intra-operative use of Raman spectroscopy in breast cancer—overcoming the effects of theatre lighting

Authors: Jonathan D. Horsnell, Catherine Kendall, Nicholas Stone

Published in: Lasers in Medical Science | Issue 6/2016

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Abstract

The ability to use Raman spectroscopy to assess tissue in the operative theatre setting could be advantageous for both patients and clinicians. In this study, a method of overcoming the deleterious effects of theatre lighting on the Raman spectra is demonstrated. The effectiveness of this technique is highlighted both within the theatre setting and using human lymph node tissue. The portable MiniRam II Raman spectroscopy device that incorporated a 785-nm laser was used in all experiments. This is an important step towards the use of Raman spectroscopy as a means of analysing sentinel lymph nodes in patients who have been newly diagnosed with breast cancer.
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Metadata
Title
Towards the intra-operative use of Raman spectroscopy in breast cancer—overcoming the effects of theatre lighting
Authors
Jonathan D. Horsnell
Catherine Kendall
Nicholas Stone
Publication date
01-08-2016
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 6/2016
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-016-1959-y

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