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Zika Virus 

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  1. Open Access 01-12-2024 | Zika Virus | OriginalPaper

    Feeding characteristics and growth among children with prenatal exposure to Zika virus with and without microcephaly in the microcephaly epidemic research group pediatric cohort

    Children with congenital Zika virus (ZIKV) infection may present with severe brain damage, neuropsychomotor developmental delays, and dysphagia, that can contribute to compromised nutrition and growth over the early life course [ 1 , 2 ]. In …

  2. Open Access 01-12-2024 | Glioblastoma | OriginalPaper

    Repurposing of Zika virus live-attenuated vaccine (ZIKV-LAV) strains as oncolytic viruses targeting human glioblastoma multiforme cells

    Glioblastoma multiforme (GBM) is the most common malignant primary brain cancer affecting the adult population. Median overall survival for GBM patients is poor (15 months), primarily due to high rates of tumour recurrence and the paucity of …

  3. Open Access 01-12-2024 | Dengue Virus | OriginalPaper

    Detecting the impacts of humidity, rainfall, temperature, and season on chikungunya, dengue and Zika viruses in Aedes albopictus mosquitoes from selected sites in Cebu city, Philippines

    While Aedes aegypti (Linnaeus) is the main vector of arboviruses such as chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV), Aedes albopictus (Skuse), the Asian tiger mosquito, plays also a role in its prevalent arboviral transmission to humans [ …

  4. 01-02-2024 | Zika Virus | OriginalPaper

    Zika virus infection during pregnancy and vertical transmission: case reports and peptide-specific cell-mediated immune responses

    Zika virus (ZIKV) infection in pregnant women is associated with birth defects, which are more prevalent and severe the earlier in pregnancy the infection occurs. Pregnant women at risk of possible ZIKV exposure (n = 154) were screened using ELISA …

  5. 29-08-2023 | Zika Virus | Erratum

    Correction: Knowledge, Attitudes and Practices About Zika Virus Infection Among Women of Reproductive Age in Central Brooklyn, New York City, USA

  6. 28-07-2023 | Zika Virus | OriginalPaper

    Knowledge, Attitudes and Practices About Zika Virus Infection Among Women of Reproductive Age in Central Brooklyn, New York City, USA

    Zika virus (ZIKV) is spread by mosquitos, sexual intercourse and vertically during pregnancy. The 2015–2016 ZIKV epidemic infected millions in the Americas and resulted in thousands of infants born with malformations. Though the clusters of severe …

  7. Open Access 01-12-2023 | Zika Virus | OriginalPaper

    Organotypic hippocampal culture model reveals differential responses to highly similar Zika virus isolates

    Zika virus (ZIKV) is an arbovirus of the Flaviviridae family, transmitted primarily through the bite of the Aedes aegypti mosquito. Infected individuals are usually asymptomatic or oligosymptomatic [ 1 ]. In 2015, Brazil faced an epidemic of Zika

  8. Open Access 01-12-2023 | Zika Virus | OriginalPaper

    Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells

    Zika virus (ZIKV) infection is a global public health concern linked to adult neurological disorders and congenital diseases in newborns. Host lipid metabolism, including lipid droplet (LD) biogenesis, has been associated with viral replication …

  9. Open Access 01-12-2023 | Zika Virus | OriginalPaper

    Interactions between DC-SIGN and the envelope protein from Dengue and Zika viruses: a structural perspective based on molecular dynamics and MM/GBSA analyses

    Zika virus (ZIKV) and dengue virus (DENV) share a lot of similarities being both phylogenetically closely related, share the same insect vector passage for reaching the host, affinity for the same carbohydrate receptor domains (CRDs), indicating …

  10. Open Access 01-12-2023 | Zika Virus | OriginalPaper

    Production of a chimeric flavivirus that contains the major structural glycoprotein genes of T’Ho virus in the genetic background of Zika virus

    T’Ho virus is a poorly characterized orthoflavivirus most closely related to Rocio virus and Ilheus virus, two orthoflaviviruses associated with human disease, suggesting that T’Ho virus could also be a human pathogen. The genome of T’Ho virus has …

  11. Open Access 01-12-2022 | Zika Virus | OriginalPaper

    Neurocognitive impact of Zika virus infection in adult rhesus macaques

    Zika virus (ZIKV) is a mosquito-borne pathogen of the Flaviviridae family of single-stranded positive RNA viruses, which includes Dengue virus (DENV), Yellow fever virus (YFV), Japanese encephalitis virus (JEV), West Nile virus (WNV) and tick-borne …

  12. Open Access 01-12-2022 | Zika Virus | OriginalPaper

    Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders

    Zika virus (ZIKV) is a mosquito-borne pathogen of global concern [ 1 ]. Like many other members of the genus Flaviviridae , ZIKV is both neuroinvasive and neurotropic [ 2 ]. Infection of the central nervous system has been linked to diverse …

  13. Open Access 01-12-2022 | Dengue Virus | OriginalPaper

    Prevalence of microcephaly and Zika virus infection in a pregnancy cohort in Kenya, 2017–2019

    In 2015, the Asian lineage of Zika virus (ZIKV), a mosquito-borne pathogen first described in Uganda in 1947, spread globally to cause widespread outbreaks in the Americas and Asia. Although more than 80% of these ZIKV infections were mild or …

  14. Open Access 01-12-2022 | Zika Virus | OriginalPaper

    Zika virus vertical transmission in interferon receptor1-antagonized Rag1−/− mice results in postnatal brain abnormalities and clinical disease

    The mechanisms by which vertically transmitted Zika virus (ZIKV) causes postnatal brain development abnormalities and congenital disease remain poorly understood. Here, we optimized the established anti-IFNAR1 treated, Rag1−/− (AIR) mouse model of …

  15. Open Access 01-12-2023 | Dengue Virus | OriginalPaper

    Investigation of the activity of baicalein towards Zika virus

    Zika virus (ZIKV), a human pathogenic virus transmitted by Aedes ( Ae .) species mosquitoes is classified as belonging to the genus Flavivirus , a part of the family Flaviviridae , together with closely related viruses such as dengue virus (DENV) …

  16. Open Access 25-07-2022 | Dengue Virus | OriginalPaper

    Preclinical evaluation of [18F]FDG-PET as a biomarker of lymphoid tissue disease and inflammation in Zika virus infection

    Zika virus (ZIKV) is a mosquito-transmitted infection affecting developing fetuses, children, and adults. It causes sporadic outbreaks, the largest of which occurred in 2015 and was declared a public health emergency of international concern by …

  17. Open Access 01-12-2022 | Zika Virus | OriginalPaper

    Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

    Zika virus (ZIKV) is a human, neurotropic, mosquito-borne flavivirus [ 1 ] first identified in 1947 in Uganda. After remaining mostly unnoticed for over 50 years, causing seroconversions and only sporadic mild febrile symptoms [ 2 ], it was …

  18. 01-08-2023 | Zika Virus | BriefCommunication

    5'/3' RACE method for sequencing the 5' and 3' untranslated regions of Zika virus

    The spread of Zika virus (ZIKV) from the African continent to the Americas promoted its molecular evolution, as reflected by mutations in its RNA genome. Most of the ZIKV genome sequences in the GenBank database have incomplete 5' and 3' UTR …

  19. Open Access 01-12-2021 | Zika Virus | OriginalPaper

    Zika virus induces neuronal and vascular degeneration in developing mouse retina

    Zika virus (ZIKV), a mosquito-borne flavivirus, can cause severe eye disease and even blindness in newborns. However, ZIKV-induced retinal lesions have not been studied in a comprehensive way, mechanisms of ZIKV-induced retinal abnormalities are …

  20. 01-12-2021 | Zika Virus

    Molecular mechanisms of Zika virus teratogenesis from animal studies: a systematic review protocol

    Zika virus (ZIKV) was first isolated from rhesus monkeys in the Zika Forest (Uganda) in 1947, and the first cases of human infection were reported in Nigeria in 1954 [ 6 , 12 ]. In 2015, a large increase of newborns with microcephaly was reported …

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