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181 search results for:

Spina Bifida Aperta 

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  1. 01-07-2018 | OriginalPaper

    Partial amniotic carbon dioxide insufflation (PACI) during minimally invasive fetoscopic interventions on fetuses with spina bifida aperta

    We retrospectively evaluated 65 cases of pregnant women undergoing minimally invasive fetoscopic patch coverage of fetal SBA under general materno-fetal anesthesia and with the help of PACI (maternal age range 19–41 years) (Table 1 ). The …

  2. 01-03-2017 | EditorialNotes

    The Italian Giuseppe Muscatello (1866–1951) and his contributions to our understanding of childhood spina bifida aperta and occulta

  3. Open Access 01-12-2007 | BriefCommunication

    Pathogenesis of cerebral malformations in perinatal spina bifida aperta

    Spina bifida aperta (SBA) is associated with cerebral morbidity, such as hydrocephalus, Chiari II malformation and cortical dysplasia. Insight in the pathogenesis of these malformations is incomplete. In fetal SBA, such information may help to …

  4. Open Access 01-12-2007 | BriefCommunication

    Muscle echogenicity is increased in fetuses with spina bifida aperta

    In spina bifida aperta (SBA), movements caudal to the meningomyelocele (MMC) are present in utero, but they disappear shortly after birth. Insight in onset and progression of movement loss is therapeutically relevant. Determination of muscle …

  5. Open Access 01-12-2004 | Abstract

    Evolution of neural function in spina bifida occulta and aperta

    Spina bifida often results in dysfunction of the central and peripheral nervous system. In spina bifida, the neural tube defect may be covered by skin (SBO) or open (SBA). Fetal surgery in SBA aims to preserve central axonal projections through …

  6. Open Access 01-12-2006 | BriefCommunication

    Histological characterisation of segmental neuromuscular dysfunction in fetuses with spina bifida aperta

    In spina bifida aperta (SBA), fetal leg movements caudal to the meningomyelocele (MMC) are quantitatively impaired and disappear shortly after birth. The time of initiation and the histological "substrate" for this motor dysfunction is still …

  7. 01-03-2013 | OriginalPaper

    In spina bifida aperta, muscle ultrasound can quantify the “second hit of damage”

    In spina bifida aperta (SBA), leg movements caudal to the myelomeningocele (MMC) are transiently present before birth but disappear shortly thereafter [ 24 – 26 ]. This phenomenon has been attributed to the “second hit of damage” involving delayed …

  8. Open Access 01-12-2005 | Abstract

    Determination of risk factors & evaluation of the outcome of patients with spina bifida aperta

    Spina Bifida is a term used for all forms of open spinal defects from myeloschisis to meningocele. The etiology & pathogenesis is still not yet clear. The risk factors and treatment aspects are still under review and debate. We have assessed …

  9. Open Access 01-02-2009 | BriefCommunication

    Can muscle ultrasound density in early life predict motor outcome in spina bifida aperta?

    Spina bifida aperta (SBA) is associated with neurological function loss caudal to the meningomyelocele (MMC). At birth, leg movements are transiently present, but they do not reliably predict motor outcome. Pediatric neuromuscular studies have …

  10. Open Access 01-12-2010 | BriefCommunication

    Neuroependymal denudation is still in progress in full-term human fetal spina bifida aperta

    Background: In human spina bifida aperta (SBA), cerebral pathogenesis (hydrocephalus, Sylvian aqueduct (SA) stenosis and heterotopias) is poorly understood. In animal models (such as hyh mutant mice) the loss of the ventricular lining (ependymal …

  11. Open Access 01-12-2010 | BriefCommunication

    Does fetal endoscopic closure of the myelomeningocele prevent loss of neurologic function in spina bifida aperta?

    Spina bifida aperta (SBA) is associated with shunt-dependent hydrocephalus and with meningomyelocele (MMC). Fetal endoscopic closure of the MMC may reduce shunt-dependency, but the benefit upon motor function in individual patients is still …

  12. Open Access 01-11-2009 | BriefCommunication

    Fetal operation followed by Caesarean section may have a beneficial effect upon neuromuscular function in spina bifida aperta

    Spina bifida aperta (SBA) is associated with neurological dysfunction cranial and caudal to the meningomyelocele (MMC). Fetal surgery may ameliorate cranial abnormalities, but effects upon neuromuscular function caudal to the MMC are unclear. SBA …

  13. 01-08-2012 | Report

    Beneficial effects following microsurgical decompression in an adult with congenital thoraco-lumbar kyphoscoliosis with spina bifida aperta and myelomeningocele: an interesting case report

    Myelomeningocele is a defect of the neural tube that occurs during the first 3–4 weeks of human embryogenesis [ 1 ]. The pathologic features of myelomeningocele include a defect of the posterior bony elements of the spine and poor viable muscular …

  14. 01-04-2009 | OriginalPaper

    Percutaneous fetoscopic patch closure of human spina bifida aperta: advances in fetal surgical techniques may obviate the need for early postnatal neurosurgical intervention

  15. Open Access 01-12-2024 | Spina Bifida | OriginalPaper

    Socioeconomic profile of families with spina bifida children in Turkey

    Spina bifida, the most common type of neural tube defect, is caused by failure of the spinal neural tube to close during the first 3 weeks of pregnancy [ 1 ]. The mildest form of it, spina bifida occulta (closed spinal dysraphism), involves a …

  16. 01-12-2024 | Neurogenic Bladder | OriginalPaper

    Bladder height to width ratio as a surrogate marker for non-physiological storage pressures in children with spinal dysraphism

    Spinal dysraphism is the most frequent cause of neurogenic bladder and McGuire et al. demonstrated that bladder pressures higher than 40 cms of water (cmH 2 O) often lead to upper tract dilatation [ 1 ]. McGuire et al. suggested that when urethral …

  17. Open Access 01-12-2024 | Spina Bifida | OriginalPaper

    Kyphectomy and sliding growing rod technique in patients with congenital lumbar kyphosis deformity with myelomeningocele

    Spina bifida (SB) occurs when arcus vertebrae lack a spinous process and stay incomplete as a result of the failure of neural tube closure which is expected to occur in the 4th week of the fetal development. SB is classified into two groups as …

  18. 02-12-2023 | Chronic Kidney Disease | OriginalPaper

    Characteristics and predictors of chronic kidney disease in children with myelomeningocele: a nationwide cohort study

    Neural tube defects (NTDs), resulting from failure of neural tube closure during early embryogenesis, consist of two main forms; anencephaly, and spina bifida (SB) including closed and open spinal defects. A myelomeningocele (MMC), also known as …

  19. 12-09-2023 | Spina Bifida Aperta | OriginalPaper

    Effect of cervical and lumbosacral spina bifida cystica on volumes of intracranial structures in children

    Neural tube defects (NTDs) are medical conditions, including two common types—spina bifida and anencephaly—that result when the spinal cord and meninges fail during the third week of embryonic development [ 1 ]. Two typical types of spina bifida

  20. Open Access 26-01-2023 | Hydrocephalus | OriginalPaper

    Endoscopic third ventriculostomy for management of hydrocephalus associated with Chiari malformation type II in children

    Chiari malformation II (CM II) refers to patients with spina bifida aperta (myelomeningocele) and hindbrain herniation. The exact incidence of hydrocephalus in CM II is not known; however, in most surgical series, the incidence of patients …

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