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1642 search results for:

Pustular Psoriasis 

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  1. Open Access 02-05-2024 | Generalized Pustular Psoriasis | Online First

    Generalized pustular psoriasis of the ‘von Zumbusch’-type: a sepsis mimic with low PCT values

  2. Open Access 16-02-2024 | Generalized Pustular Psoriasis | ReviewPaper

    Clinical and Disease Burden of Patients with Generalized Pustular Psoriasis: A Review of Real-World Evidence

    Generalized pustular psoriasis (GPP) is a chronic, rare, and potentially life-threatening disease. There is limited understanding of patient characteristics in GPP and their correlation with disease progression or healthcare resource utilization.

  3. Open Access 02-12-2023 | Generalized Pustular Psoriasis | OriginalPaper

    Commentary: Unmet Needs in Generalized Pustular Psoriasis in Clinical Practice

    Generalized pustular psoriasis (GPP) is a rare and chronic inflammatory skin disease characterized by recurrent flares of pustulation with or without systemic inflammation that can be life-threatening if not appropriately treated [ 1 – 4 ]. GPP …

  4. Open Access 20-12-2023 | Generalized Pustular Psoriasis | ReviewPaper

    Spesolimab for the Treatment of Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare but severe skin inflammatory disorder characterized by the eruption of widespread sterile neutrophilic pustules, often accompanied by systemic inflammation. Given its life-threatening potential, GPP …

  5. 02-12-2023 | Pustular Psoriasis | ReviewPaper

    Spesolimab in generalised pustular psoriasis flares: a profile of its use

    Spesolimab (Spevigo®) is a promising new treatment for generalised pustular psoriasis (GPP) flares. GPP is a rare and life-threatening autoinflammatory disease characterized by flares of widespread skin lesions with pustules, which may be …

  6. Open Access 16-10-2023 | Generalized Pustular Psoriasis | OriginalPaper

    Efficacy and Safety of Spesolimab in Patients with Generalized Pustular Psoriasis: A Subgroup Analysis of Chinese Patients in the Effisayil 1 Trial

    Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening skin disease, characterized by irregular, acute and recurrent flares of sterile pustules, with or without systemic inflammation [ 1 , 2 ]. The prevalence of the disease …

  7. 29-06-2023 | Generalized Pustular Psoriasis | OriginalPaper

    Characteristics and Burdens of Disease in Patients from Beijing with Generalized Pustular Psoriasis and Palmoplantar Pustulosis: Multicenter Retrospective Cohort Study Using a Regional Database

    Pustular psoriasis (PP) is a type of psoriasis that is characterized by superficial sterile pustules and erythematous plaques, and is classified as localized PP or generalized PP (GPP) based on lesion distribution [ 1 ]. Early lesions present as …

  8. Open Access 08-10-2022 | Generalized Pustular Psoriasis | Letter

    Commentary on a Clinical Trial of Spesolimab, a Humanized Anti-interleukin-36 Receptor Monoclonal Antibody, in Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare and potentially life-threatening autoinflammatory skin disease, mainly mediated by the interleukin (IL)-36 signaling pathway. The irregular and relapsing pattern of the skin symptoms, the …

  9. Open Access 01-02-2022 | Generalized Pustular Psoriasis | OriginalPaper

    Ixekizumab 80 mg Every 2 Weeks Treatment Beyond Week 12 for Japanese Patients with Generalized Pustular Psoriasis and Erythrodermic Psoriasis

    Psoriasis is a common chronic skin disorder with an estimated prevalence of up to 3% worldwide [ 1 – 3 ], with lower rates of 1% observed in the Japanese population [ 4 ]. Generalized pustular psoriasis (GPP) and erythrodermic psoriasis (EP) are …

  10. 01-06-2020 | Etanercept | OriginalPaper

    Pharmacological Management of Pediatric Pustular Psoriasis

    Therapeutic management of pustular psoriasis remains a challenge despite the rapid advance in psoriasis research and the development of drugs, especially biologics. Treatment guidelines have been established for pustular psoriasis, but no …

  11. Open Access 13-01-2023 | Generalized Pustular Psoriasis | ReviewPaper

    Generalized Pustular Psoriasis: A Review on Clinical Characteristics, Diagnosis, and Treatment

    Generalized pustular psoriasis (GPP) is a rare, chronic, and severe inflammatory skin disorder characterized by sudden eruption of sterile pustules, often accompanied by systemic inflammation. GPP flares can be life-threatening if untreated, owing …

  12. 15-06-2022 | Generalized Pustular Psoriasis | ReviewPaper

    Generalized Pustular Psoriasis in Pregnancy: Current and Future Treatments

    Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin disease characterized by sudden widespread eruption of sterile pustules with or without systemic symptoms. GPP may be life threatening in cases with severe complications such …

  13. Open Access 19-05-2022 | Generalized Pustular Psoriasis | OriginalPaper

    Symptom Experience and Content Validity of the Psoriasis Symptom Scale (PSS) in Patients with Generalized Pustular Psoriasis (GPP)

    Generalized pustular psoriasis (GPP) is a severe and rare disease [ 1 ], associated with erythema and pustules either with or without fever and other systemic symptoms [ 2 , 3 ]. GPP may either be preceded by plaque psoriasis or arise de novo [ 4 – …6

  14. Open Access 27-05-2022 | Certolizumab | OriginalPaper

    Efficacy and Safety of Certolizumab Pegol in Japanese Patients with Generalized Pustular Psoriasis and Erythrodermic Psoriasis: 52-Week Results

    Generalized pustular psoriasis (GPP) and erythrodermic psoriasis (EP) are severe and potentially life-threatening forms of psoriasis [ 1 ]. Patients with GPP experience recurrent flare-ups of sudden widespread sterile pustulosis [ 2 ], while …

  15. Open Access 01-01-2022 | Generalized Pustular Psoriasis | ReviewPaper

    Diagnosis of Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a severe rare skin disease characterized by widespread eruption of sterile superficial macroscopic pustules with or without systemic inflammation. Generalized pustular psoriasis flares may lead to …

  16. Open Access 01-01-2022 | Generalized Pustular Psoriasis | ReviewPaper

    Pathophysiology of Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare, severe form of pustular psoriasis characterized by widespread, recurrent episodes of neutrophil-rich pustule formation in the epidermis, which can be accompanied by fever and systemic inflammation.

  17. Open Access 01-01-2022 | Generalized Pustular Psoriasis | ReviewPaper

    Clinical Disease Measures in Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare neutrophilic skin condition characterized by episodes of widespread eruption of sterile macroscopic pustules that can be associated with systemic inflammation. The rarity of GPP and its heterogeneous …

  18. Open Access 01-02-2022 | Pustular Psoriasis | ReviewPaper

    Role of Interleukin 36 in Generalised Pustular Psoriasis and Beyond

    Generalised pustular psoriasis (GPP), a severe neutrophilic skin disease characterised by the sudden and widespread eruption of superficial sterile pustules, remains a challenging disease with limited treatment options. The recent discovery of …

  19. Open Access 01-01-2022 | Generalized Pustular Psoriasis | ReviewPaper

    The Prevalence and Disease Characteristics of Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare disease that has only recently benefited from a consistent definition and clinical coding standard. A lack of disease awareness combined with clinical similarities to other types of psoriasis have …

  20. Open Access 01-01-2022 | Generalized Pustular Psoriasis | ReviewPaper

    Treatment Options and Goals for Patients with Generalized Pustular Psoriasis

    Generalized pustular psoriasis (GPP) is a rare, severe neutrophilic skin disorder characterized by sudden widespread eruption of superficial sterile pustules with or without systemic inflammation. GPP flares can be life-threatening if untreated …

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