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823 search results for:

Juvenile Myoclonic Epilepsy 

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  1. 04-05-2024 | Juvenile Myoclonic Epilepsy | Online First

    Alterations in spatiotemporal characteristics of dynamic networks in juvenile myoclonic epilepsy

    Juvenile myoclonic epilepsy (JME) is a prevalent epilepsy syndrome, typically emerging around the period of adolescence. It is primarily characterized by recurrent and irregular myoclonic seizures, manifesting as bilateral or unilateral arm …

  2. 21-04-2024 | Juvenile Myoclonic Epilepsy | Online First

    Transcranial brain parenchyma sonography in patients with juvenile myoclonic epilepsy

    Juvenile myoclonic epilepsy (JME) is a common idiopathic generalized epilepsy (IGE) syndrome, affecting 5 to 10% of people with epilepsy. It is an age-related condition usually starting between 12 and 18 years, more frequently affecting females.

  3. 14-05-2024 | Juvenile Myoclonic Epilepsy | Online First

    Deep brain stimulation of the subthalamic nucleus for a patient with drug resistant juvenile myoclonic epilepsy: 1 year follow-up

    Juvenile myoclonic epilepsy (JME), or Janz Syndrome, is a prevalent form of genetic or idiopathic-generalized epilepsy (IGE) in adolescents, with a reported prevalence ranging from 1 to 3 per 10000 persons in population-based studies 1 , 2 . In …

  4. 25-10-2023 | Juvenile Myoclonic Epilepsy | OriginalPaper

    Association of variants in the ABCB1, CYP2C19 and CYP2C9 genes for Juvenile Myoclonic Epilepsy

    Juvenile myoclonic epilepsy (JME) is the most common of the generalized genetic epilepsies, with multiple causal and susceptibility genes; however, its etiopathogenesis is mainly unknown. The toxic effects caused by xenobiotics in cells occur …

  5. 23-10-2023 | Epilepsy | News | Article

    Levetiracetam superior to lamotrigine for women with juvenile myoclonic epilepsy

    Levetiracetam may be a better option than lamotrigine for first-line treatment of juvenile myoclonic epilepsy in women of childbearing age, suggest study findings. 

  6. Open Access 01-12-2022 | Juvenile Myoclonic Epilepsy | OriginalPaper

    Altered brain activity in juvenile myoclonic epilepsy with a monotherapy: a resting-state fMRI study

    Juvenile myoclonic epilepsy (JME) is the most common syndrome of idiopathic generalized epilepsy (IGE) [ 1 ]. JME is characterized by myoclonic jerks, sometimes with generalized tonic-clonic seizures and less frequently with absence seizures. It …

  7. 20-05-2022 | Juvenile Myoclonic Epilepsy | OriginalPaper

    School performance and psychiatric comorbidity in juvenile absence epilepsy and juvenile myoclonic epilepsy: a Danish population-based cohort study

    Idiopathic generalized epilepsy (IGE) constitutes childhood absence epilepsy, juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and generalized tonic–clonic seizures (GTCS) alone [ 1 ]. JME is the most common IGE with onset …

  8. 12-10-2022 | Folic Acid | Letter

    A healthy outcome of a pregnant woman with drug-resistant juvenile myoclonic epilepsy treated with brivaracetam

  9. 01-04-2022 | Juvenile Myoclonic Epilepsy | OriginalPaper

    Glymphatic system dysfunction in patients with juvenile myoclonic epilepsy

    The glymphatic system is glial cell-dependent waste clearance pathway in the brain that is essential for the maintenance of brain homeostasis [ 1 – 3 ]. The name “glymphatic system” was coined by combining “G” from “glia” with “lymphatic system.”[ …

  10. 01-12-2022 | Juvenile Myoclonic Epilepsy | Original Research

    Comparative analysis of background EEG activity in juvenile myoclonic epilepsy during valproic acid treatment: a standardized, low-resolution, brain electromagnetic tomography (sLORETA) study

    Juvenile myoclonic epilepsy (JME) is the most common and well-defined generalized epilepsy syndrome. It usually begins in adolescence, with a peak onset between 12 and 18 years [ 1 , 2 ]. JME is characterized by myoclonic seizures, especially …

  11. 01-05-2019 | Juvenile Myoclonic Epilepsy | OriginalPaper

    Methylation of cation–chloride cotransporters NKCC1 and KCC2 in patients with juvenile myoclonic epilepsy

    The etiology of juvenile myoclonic epilepsy (JME) is still unknown and the process of elaboration of multiple genetic mechanisms is ongoing. The aim of this study was to investigate the potential role of NKCC1 (SCL12A2) and KCC2 (SCL12A5) in JME …

  12. 01-03-2019 | Contraception | OriginalPaper

    Treatment of Juvenile Myoclonic Epilepsy in Patients of Child-Bearing Potential

    Juvenile myoclonic epilepsy (JME) is both a frequent and a very characteristic epileptic syndrome with female preponderance. Treatment of JME in women of childbearing potential must consider multiple factors such as desire for pregnancy, use of …

  13. 01-03-2020 | Juvenile Myoclonic Epilepsy | OriginalPaper

    Whole exome sequencing identifies a novel SCN1A mutation in genetic (idiopathic) generalized epilepsy and juvenile myoclonic epilepsy subtypes

    Genetic (idiopathic) generalized epilepsy (GGE) is a group of age-related epilepsies characterized by generalized seizures with EEG showing generalized spikes, polyspikes, or spike/polyspike-and-wave complexes. GGE is a common form of epilepsy

  14. 01-09-2006 | ReviewPaper

    Juvenile Myoclonic Epilepsy

    Epidemiology, Pathophysiology, and Management

    Juvenile myoclonic epilepsy (JME) is a common epilepsy syndrome that begins most frequently in the early teenage years. It is officially classified as a type of idiopathic generalized epilepsy and is often under-recognized or misdiagnosed. This …

  15. 01-01-2001 | Abstract

    Carbamazepine, and to a lesser extent, phenytoin, aggravates juvenile myoclonic epilepsy

  16. 01-03-2018 | OriginalPaper

    Prevalence and clinical characteristics of headache in juvenile myoclonic epilepsy: experience from a tertiary epilepsy center

    The comorbidity of headache and epilepsy is often seen in neurological practice. The objective of this study was to assess the prevalence, types of, and risk factors for headache in juvenile myoclonic epilepsy (JME). We assessed a total of 200 …

  17. 01-04-2017 | Letter

    Juvenile myoclonic epilepsy and Brugada type 1 ECG pattern associated with (a novel) plakophillin 2 mutation

  18. 01-06-2013 | OriginalPaper

    Oxcarbazepine-induced myoclonic status epilepticus in juvenile myoclonic epilepsy

    Juvenile myoclonic epilepsy (JME) is a frequent idiopathic generalised epilepsy syndrome with typical clinical and EEG features that can usually be controlled by valproate monotherapy. JME may be underdiagnosed or misdiagnosed; in the latter case …

  19. 01-09-2011 | OriginalPaper

    Fronto-polar epilepsy masquerading as juvenile myoclonic epilepsy

    A woman diagnosed with juvenile myoclonic epilepsy for over 30 years presented with stereotyped episodes of abnormal sensations in both arms. Continuous video-EEG monitoring for 14 days and MRI brain revealed that the patient’s somatosensory …

  20. 01-07-2015 | BriefCommunication

    Auditory startle response is normal in juvenile myoclonic epilepsy

    Juvenile myoclonic epilepsy (JME) is hypothesized to originate from the dysfunction of thalamo-cortical circuit. We aimed to analyze any changes in auditory startle response in JME patients to determine the role of brainstem in JME. The responses …

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