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Hyperhidrosis 

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  1. Open Access 27-04-2024 | Hyperhidrosis | Online First

    Single-center experience of thoracoscopic sympathectomy for palmar hyperhidrosis with long-term postoperative questionnaire survey

    Palmar hyperhidrosis is a sympathetic disorder defined by excessive secretion of exocrine glands on the palms [ 1 ], and it affects 0.6–10.4% of the general population [ 2 , 3 ]. It is caused by hyperfunctioning of the sympathetic nervous system …

  2. 04-03-2024 | Hyperhidrosis | BriefCommunication

    A novel pathogenic variant in TDP2 causes spinocerebellar ataxia autosomal recessive 23 accompanied by pituitary tumor and hyperhidrosis: a case report

    TDP2 gene encodes tyrosyl DNA phosphodiesterase 2, an enzyme required for effective repair of the DNA double-strand breaks (DSBs). Spinocerebellar ataxia autosomal recessive 23 (SCAR23) is a rare disease caused by the pathogenic mutation of TDP2 …

  3. Open Access 01-03-2024 | Hyperhidrosis | Report

    Botulinum Toxin A and B for Palmoplantar Hyperhidrosis

    Hyperhidrosis is characterized by unpredictable, uncontrollable and excessive sweating. It occurs at rest and is not related to temperature. Most often it affects the axillae, palms and soles, but it may also involve the groin, face or any …

  4. 20-05-2023 | Hyperhidrosis | BriefCommunication

    Teaching neuro-image: a case of gustatory hyperhidrosis

  5. 12-02-2024 | Hyperhidrosis | Online First

    Use of The Rubbing Grid Paper for Injection Guidance in Botulinum Toxin A Treatment of Hyperhidrosis

  6. 31-10-2023 | Amyotrophic Lateral Sclerosis | OriginalPaper

    Hyperhidrosis as the initial symptom in FUS mutation-associated amyotrophic lateral sclerosis: a case report and comprehensive literature review

    Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord, leading to the loss of motor function and eventually causing paralysis and death. The exact causes of ALS are not …

  7. Open Access 01-12-2023 | Oxybutynin | OriginalPaper

    Pharmacovigilance-based drug repurposing: searching for putative drugs with hypohidrosis or anhidrosis adverse events for use against hyperhidrosis

    Drug repurposing is the process of identifying and developing novel disease indications for approved drugs [ 1 ]. The advantage of drug repurposing over conventional drug development is that it can reduce the time, cost, and risk of failure …

  8. Open Access 01-12-2023 | Hyperhidrosis | OriginalPaper

    PAI1 inhibits the pathogenesis of primary focal hyperhidrosis by targeting CHRNA1

    Hyperhidrosis is a dermatosis pathologically characterized by excessive generalized or localized (focal) sweating. Focal hyperhidrosis (PFH) is the most common form, and exocrine glands are overactive due to sympathetic nervous system dysfunction …

  9. 20-07-2023 | Hyperhidrosis | OriginalPaper

    Anatomical proposal of local anesthesia injection for median nerve block in treating hyperhidrosis with botulinum neurotoxin

    The eccrine sweat glands regulate body temperature by the secretion of sweat, which is induced by the sympathetic nervous system in response to a rise in body temperature, which, in turn, may be accelerated by a thermal stimulus or exercise [ 18 ].

  10. Open Access 01-12-2022 | Sympathectomy | ReviewPaper

    Spontaneous ventilation anesthesia combined with uniportal and tubeless thoracoscopic sympathectomy in selected patients with primary palmar hyperhidrosis

    Primary palmar hyperhidrosis (PPH) is a disorder of unknown etiology characterized by excessive sweating of the hands, feet, and armpits. This disorder can have serious social, emotional, and professional impacts, especially in young adult and …

  11. 28-07-2023 | Hyperhidrosis | ReviewPaper

    Quality of life in individuals with primary hyperhidrosis: a systematic review and meta-analysis

    Hyperhidrosis (HH), defined as focal and visible pathologically excessive sweating without an apparent cause for at least 6 months, can be a debilitating disease that degrades the patients’ everyday health-related quality of life (HRQOL) [ 1 – 8 ].

  12. Open Access 01-12-2023 | Sympathectomy | OriginalPaper

    Rhomboid intercostal block versus serratus block for postoperative analgesia after thoracoscopic sympathectomy for primary palmar hyperhidrosis: a randomized controlled trial

    Primary palmar hyperhidrosis is a disorder characterized by chronic excessive sweating despite the absence of sweating triggers. With the evolution of surgical approaches, upper thoracic dorsal sympathectomy performed via video-assisted …

  13. 03-06-2023 | Hyperhidrosis | OriginalPaper

    The differentiating effect of COVID-19-associated stress on the morbidity of blood donors with symptoms of hidradenitis suppurativa, hyperhidrosis, or psoriasis

    1. Why is this study needed? Different skin diseases can affect patients differently during times of universal stress, such as during the Covid-19 pandemic. By identifying the skin diseases that can worsen the well-being of patients during such a …

  14. Open Access 04-03-2023 | Oxybutynin | ReviewPaper

    Safety and efficacy of oxybutynin in patients with hyperhidrosis: systematic review and meta-analysis of randomized controlled trials

    Sweating is a physiologic mechanism of human thermoregulation [ 1 ]. Hyperhidrosis is defined as a somatic disorder where the sweating is exaggerated in an exact area because the sweat glands are hyperfunctioning [ 1 , 2 ]. The eccrine glands are …

  15. 20-05-2023 | Oxybutynin | OriginalPaper

    Treat hyperhidrosis with topical therapies first, then dermatological or systemic therapies

    Hyperhidrosis (HH) includes chronic focal primary HH (PHH) stemming from sweat gland overactivity, and generalised secondary HH (SHH), which warrants investigation for an underlying cause. PHH, which may be axillary, plantar, palmar and/or …

  16. Open Access 01-12-2023 | Sympathectomy | OriginalPaper

    Comparison of the efficacy of ETS with different segments for palmar, axillary and plantar hyperhidrosis

    Primary palmar hyperhidrosis is a condition characterized by excessive hyperhidrosis of the palms of the hands. The etiology of primary palmar hyperhidrosis remains unclear. The prevalence of hyperhidrosis in the United States was 2.8% in 2004 [ 1 …

  17. Open Access 01-12-2021 | Sympathectomy | OriginalPaper

    Bilateral one-stage single-port sympathicotomy in primary focal hyperhidrosis, a prospective cohort study: treat earlier?

    Hyperhidrosis is a pathologic condition in which sweat production exceeds the need for physiological thermoregulation. It may develop secondary to psychological causes or a variety of medical disorders, but is mostly cryptogenic / primary, thus …

  18. Open Access 05-04-2023 | Thoracoscopy | OriginalPaper

    Anatomical variations of the thoracic sympathetic ganglions and their effects on sympathicotomy for primary palmar hyperhidrosis

    Endoscopic thoracic sympathicotomy (ETS) has been accepted as the most effective method for the treatment of primary palmar hyperhidrosis (PPH), especially for those with a poor outcome from conservative treatments. The optimal level of …

  19. 01-02-2021 | CO2 Laser | Report

    Fractional CO2 laser-assisted Botulinum toxin type A delivery for the treatment of primary palmar hyperhidrosis

    Intradermal injections of botulinum toxin type A (BTX-A) have been used successfully to treat patients with primary palmoplantar hyperhidrosis (PPH). However, problems with local injections of BTX-A for palmar hyperhidrosis include injection pain …

  20. 01-12-2020 | Thoracic Pain | Original Research

    Video-assisted thoracoscopic sympathectomy versus modified Wittmoser method in surgical management of primary hyperhidrosis

    Primary hyperhidrosis (PHH) involves a series of pathophysiological mechanisms and characterized by an idiopathic, chronic, usually focal, bilateral and symmetrical sweating manifesting itself in all seasons and exacerbated by stress, anxiety …

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