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2292 search results for:

Gastrointestinal Amyloidosis 

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  1. Open Access 02-09-2023 | AL Amyloidosis | ReviewPaper

    Peripheral Nervous, Hepatic, and Gastrointestinal Endpoints for AL Amyloidosis Clinical Trials: Report from the Amyloidosis Forum Multi-organ System Working Group

    Systemic immunoglobulin light chain (AL) amyloidosis is a heterogeneous rare disease driven by a destructive monoclonal gammopathy and typified by misfolded immunoglobulin light and/or heavy chains which aggregate and deposit in organs as …

  2. Intra-abdominal bleeding caused by amyloid transthyretin amyloidosis in the gastrointestinal tract: a case report

    Diagnosis of gastrointestinal (GI) amyloidosis is often very difficult because of its nonspecific symptoms. However, a few reports have indicated that serious symptoms such as fatal GI bleeding and obstruction or perforation sometimes lead to a …

  3. Open Access 01-12-2021 | Multiple Myeloma | OriginalPaper

    Gastric amyloidosis presenting as acute upper gastrointestinal bleeding: a case report

    Upper gastrointestinal bleeding (UGIB) is a common cause of emergency department visits and hospital admissions. Peptic ulcer disease, gastritis, and esophagitis have shared risk factors and are the most common causes of UGIB, accounting for 79% …

  4. Gastrointestinal AA amyloidosis secondary to chronic pyelonephritis presenting with refractory diarrhea and severe hypoalbuminemia

    Secondary amyloidosis is a rare complication of chronic inflammatory diseases, such as collagen diseases, and is often difficult to treat. In addition, the gastrointestinal tract is frequently involved in amyloid deposition that often results in …

  5. Open Access 01-09-2019 | Constipation | ReviewPaper

    Diagnosis and treatment of gastrointestinal dysfunction in hereditary TTR amyloidosis

    Several manifestations of hereditary transthyretin amyloidosis (ATTRv) are related to the early and progressive damage to the autonomic nervous system. Similar to diabetic autonomic neuropathy, impairment of the enteric nervous system and its …

  6. Open Access 01-06-2019 | OriginalPaper

    Primary gastrointestinal amyloidosis with gastrointestinal hemorrhage and intestinal pseudo-obstruction: a report of a rare case

    Amyloidosis is a syndrome involving amyloid protein deposition in various organs, resulting in organ dysfunction. Symptoms of gastrointestinal amyloidosis are usually nonspecific, such as diarrhea and body weight loss. We, here, report a patient …

  7. 01-03-2017 | OriginalPaper

    Gastric Outlet Obstruction due to Gastrointestinal Amyloidosis

    A 64- year-old man with smoldering myeloma presented to the hospital for nausea, vomiting, and PO intolerance. Abdominal CT demonstrated massive gastric distention and collapsed proximal duodenum consistent with gastric outlet obstruction (GOO).

  8. 01-08-2011 | OriginalPaper

    Peritoneal amyloidosis: unusual localization of gastrointestinal amyloidosis

    Amyloidosis is a rare disease that results from the extracellular deposition of amorphous fibrillar protein. It is usually observed in a systemic form. Gastrointestinal involvement is frequent but peritoneal localization is unusual. A 43-year-old …

  9. 01-05-2009 | OriginalPaper

    Gastrointestinal Amyloidosis Presenting with Multiple Episodes of Gastrointestinal Bleeding

    Amyloidosis is characterized by the extracellular deposition of amyloid protein in various organs. Gastrointestinal involvement in amyloidosis is common, but a diagnosis of amyloidosis is often delayed. Severe gastrointestinal hemorrhage in …

  10. Open Access 01-12-2015 | OriginalPaper

    Treatment of gastrointestinal complication in transthyretin amyloidosis. A single centre’s experience

    Gastrointestinal complications have a substantial impact on ATTR amyloidosis patients’ survival and quality of life.

  11. 01-04-2012 | ReviewPaper

    Gastrointestinal manifestation of amyloidosis

    There has been an enormous progress in the understanding of the pathogenesis, classification, clinical feature, diagnosis and treatment of amyloidosis over the past decades. Irrespective of the type of amyloidosis the amyloid protein can deposit …

  12. 01-02-2015 | OriginalPaper

    Gastrointestinal Amyloidosis and Multiple Myeloma

  13. 01-01-2003 | OriginalPaper

    Gastrointestinal amyloidosis: Approach to treatment

    The main treatment goals in amyloidosis are twofold: 1) to diagnose the underlying disease state accurately to guide effective primary therapy (if available) and 2) to ameliorate symptoms. The correct diagnosis is essential because …

  14. Open Access 01-12-2015 | OriginalPaper

    Outcome of gastric emptying and gastrointestinal symptoms after liver transplantation for hereditary transthyretin amyloidosis

    Hereditary transthyretin amyloid (ATTR) amyloidosis or familial amyloid polyneuropathy (FAP) is a rare autosomal dominant disease caused by mutated transthyretin (TTR). The disease is present all over the world with endemic areas in Sweden …

  15. 01-06-2007 | OriginalPaper

    A huge fecalith associated with dialysis-related gastrointestinal amyloidosis

    A 60-year-old man who had been receiving dialysis for more than 30 years was admitted for treatment of cellulitis in his right thigh on November 7, 2003. He suffered from an ileus on December 14 and was found to have a huge, 7-cm-diameter …

  16. 01-03-2012 | Letter

    AL amyloidosis with severe gastrointestinal invasion and acute obstructive suppurative cholangitis

  17. 01-10-2003 | OriginalPaper

    CASE REPORT: Gastrointestinal Amyloidosis with Ulceration, Hemorrhage, Small Bowel Diverticula, and Perforation

  18. 01-08-1998 | OriginalPaper

    Case Report: Gastrointestinal Amyloidosis Secondary to Hypersensitivity Vasculitis Presenting with Intestinal Pseudoobstruction

    Hypersensitivity vasculitis is characterized byinflammation and necrosis of small blood vesselssecondary to allergic or hypersensitivity mechanisms (1,2). Gastrointestinal involvement with edema and bleeding also has been reported …

  19. Open Access 01-12-2014 | OriginalPaper

    THAOS: Gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease

    Transthyretin amyloid (ATTR) amyloidosis is a systemic disorder with two main forms; hereditary and wild-type (wt) ATTR amyloidosis. The hereditary form is caused by transthyretin (TTR) gene mutations and is sometimes referred to as familial …

  20. 01-12-2003 | OriginalPaper

    The burden of amyloidosis on the gastrointestinal tract of an ankylosing spondylitis patient

    We present a 26-year-old man with edema, ascites and bloody diarrhea that later proved to be due to gastrointestinal and renal amyloidosis. Interestingly, he was also diagnosed as having ankylosing spondylitis,-possibly after a delay of 12 years.

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