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Francisella Tularensis 

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  1. Open Access 13-03-2023 | Lung Cancer | BriefCommunication

    Rabbit fever: granulomatous inflammation by Francisella tularensis mimics lung cancer in dual tracer 18FDG and 68Ga-FAPI PET/CT

  2. Open Access 01-12-2021 | Tularemia | OriginalPaper

    Francisella tularensis human infections in a village of northwest Iran

    Tularemia is a zoonotic disease caused by the Gram-negative bacterium Francisella tularensis [ 1 ]. The disease classically manifests by six clinical forms, the ulceroglandular, glandular, oculoglandular, oropharyngeal, respiratory, and typhoidal …

  3. Open Access 01-12-2020 | Francisella Tularensis | OriginalPaper

    Francisella tularensis as the cause of protracted fever

    Tularemia is a rare but potentially life threatening zoonosis, and it is well recognized as a (re-) emerging disease in Austria [ 1 – 3 ], as well as in other European countries [ 4 – 7 ]. There are existing several clinical forms, of which most …

  4. Open Access 01-12-2019 | Antibiotic | OriginalPaper

    Lymph node abscess caused by Francisella tularensis – a rare differential diagnosis for cervical lymph node swelling: a case report

    Cervical lymph node swelling is found in many different disciplines from general medicine to specialized disciplines such as otorhinolaryngology or craniomaxillofacial surgery. Reasons for the swelling might be benign or malign diseases. Benign …

  5. Open Access 01-12-2019 | Pneumonia | OriginalPaper

    Severe infections due to Francisella tularensis ssp. holarctica in solid organ transplant recipient: report of two cases and review of literature

    Tularemia is an infrequent bacterial disease caused by Gram negative coccobacillus Francisella tularensis . The annual mean incidence in France is 0.07 cases per 100.000 inhabitants, rising up to between 0.16 and 0.20 per 100.000 inhabitants in the …

  6. 01-04-2016 | BriefCommunication

    Francisella tularensis aortitis

    Francisella tularensis, the agent of tularemia, is a Gram-negative coccobacillus primarily pathogen for animals and occasionally for humans. The clinical manifestations of tularemia include pneumonia, ulceroglandular, oropharyngeal, or typhoidal …

  7. 01-12-1998 | OriginalPaper

    First isolation of Francisella tularensis subsp. tularensis in Europe

    Francisella tularensis subsp. tularensis is the common causal agent of tularemia in the USA and Canada, while F. tularensis subsp. palaearctica (holarctica) occurs in Europe, Asia, and to a minor extent in North America. F. tularensis subsp.

  8. Open Access 01-12-2016 | OriginalPaper

    Mitogen-activated protein kinases (MAPKs) are modulated during Francisella tularensis infection, but inhibition of extracellular-signal-regulated kinases (ERKs) is of limited therapeutic benefit

    Francisella tularensis is a Gram-negative intracellular bacterium that causes the disease tularemia. The disease can be fatal if left untreated and there is currently no licenced vaccine available; the identification of new therapeutic targets is …

  9. 01-01-2003 | OriginalPaper

    Fatal infection caused by Francisella tularensis in a neutropenic bone marrow transplant recipient

    Francisella tularensis is one of the most infectious pathogenic bacteria known. Even though immunity against this organism is thought to be primarily T cell mediated, some evidence suggests that neutrophils may also play an important protective …

  10. 01-03-2007 | OriginalPaper

    Simultaneous real-time PCR detection of Bacillus anthracis, Francisella tularensis and Yersinia pestis

    This report describes the development of in-house real-time PCR assays using minor groove binding probes for simultaneous detection of the Bacillus anthracis pag and cap genes, the Francisella tularensis 23 KDa gene, as well as the Yersinia pestis …

  11. Open Access 01-12-2008 | OriginalPaper

    Pericardial effusion as the only manifestation of infection with Francisella tularensis: a case report

    Tularemia, caused by the facultative intracellular Gram-negative bacterium Francisella tularensis , is endemic in certain areas of the northern hemisphere. In France, it is a rare disease, being diagnosed mainly in the north-eastern part of the …

  12. Open Access 01-12-2011 | OriginalPaper

    Eschar and neck lymphadenopathy caused by Francisella tularensis after a tick bite: a case report

    In 1997, Raoult et al. described a new tick-borne disease caused by Rickettsia slovaca in a patient presenting with a single inoculation lesion of the scalp and cervical lymphadenopathy [ 1 ]. In the same year, Lakos reported 27 cases of …

  13. 01-04-2008 | BriefCommunication

    The presence of infectious extracellular Francisella tularensis subsp. novicida in murine plasma after pulmonary challenge

  14. 01-09-2011 | Report

    Evidence of circulation of an epidemic strain of Francisella tularensis in France by multispacer typing

    Multispacer typing (MST) was used to type ten Francisella tularensis strains detected in French patients. Incorporating 79 Swedish F. tularensis strains, phylogenetic analysis demonstrated that although tularemia appears as a sporadic disease in …

  15. Open Access 01-12-2010 | Report

    CpG oligodeoxyribonucleotides protect mice from Burkholderia pseudomallei but not Francisella tularensis Schu S4 aerosols

    Studies have shown that CpG oligodeoxyribonucleotides (ODN) protect mice from various bacterial pathogens, including Burkholderia pseudomallei and Francisella tularensis live vaccine strain (LVS), when administered before parenteral challenge.

  16. Open Access 01-12-2010 | OriginalPaper

    Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection

    Tularemia is caused by the Gram-negative, non-motile, intracellular coccobacillus, Francisella tularensis (Ft) , so named after Tulare county of California where the disease was initially identified [ 1 ]. Rodents, along with rabbits and hares, are …

  17. 01-12-2009 | OriginalPaper

    An approach to the identification of T cell epitopes in the genomic era: application to Francisella tularensis

    The identification and characterization of epitopes is essential for modern immunologic studies. Here, we describe a novel methodology we have developed to identify T cell epitopes exploiting the phenomenon of cross presentation. Particulate …

  18. Open Access 01-12-2008 | OriginalPaper

    Re-emergence of tularemia in Germany: Presence of Francisella tularensis in different rodent species in endemic areas

    Tularemia is caused by the gram-negative rod Francisella (F.) tularensis which is confined to the Northern Hemisphere, where small mammals such as rabbits, hares and voles are known to be involved in enzootic transmission cycles [ 1 ]. F.

  19. 01-09-2012 | OriginalPaper

    Identification of Francisella tularensis by both culture and real-time TaqMan PCR methods from environmental water specimens in outbreak areas where tularemia cases were not previously reported

    Tularemia is an endemic disease in Turkey. In this study, we aimed to detect Francisella tularensis by two methods from natural water supplies thought to cause tularemia epidemiologically. A total of 154 water specimens from three different …

  20. 01-07-2000 | OriginalPaper

    Swiss Army Survey in Switzerland to Determine the Prevalence of Francisella tularensis, Members of the Ehrlichia phagocytophila Genogroup, Borrelia burgdorferi Sensu Lato, and Tick-Borne Encephalitis Virus in Ticks

     A total of 6071 Ixodes ricinus ticks were collected on Swiss Army training grounds in five regions of Switzerland. The aim of the survey was to assess the prevalence of ticks infected with the human pathogens Francisella tularensis, members of …

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