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342 search results for:

Fesoterodine 

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  1. 06-06-2022 | Overactive Bladder | OriginalPaper

    On-demand use of fesoterodine: a new paradigm for extended release antimuscarinics

    Overactive bladder (OAB) is defined by the ICS as ‘urinary urgency, usually accompanied by frequency and nocturia, with or without UUI, in the absence of urinary tract infection or other obvious pathology’ [ 1 ]. Antimuscarinics are the mainstay of …

  2. Open Access 09-03-2023 | Overactive Bladder | OriginalPaper

    Population Pharmacokinetic and Pharmacodynamic Modeling of Fesoterodine in Pediatric Patients with Neurogenic Detrusor Overactivity

    Neurogenic detrusor overactivity (NDO) is the involuntary contraction of the detrusor muscle as the bladder fills [ 1 – 4 ]. It may be necessary to perform clean intermittent catheterization for children with NDO to achieve continence and prevent …

  3. 01-11-2021 | Fesoterodine | News

    Fesoterodine

    First report of digital ischaemia: case report
  4. Fesoterodine/oxybutynin

    Headache, behavioural changes with severe mental retardation and increased appetitie: 3 case reports
  5. 01-08-2020 | Overactive Bladder | OriginalPaper

    Randomized, controlled trial of fesoterodine fumarate for overactive bladder in Parkinson’s disease

    Parkinson’s disease (PD) is an extrapyramidal neurologic disorder caused by the progressive degeneration of pigmented cells in the substantia nigra. Lower urinary tract symptoms (LUTS) often accompany the PD and in the actual literature, the …

  6. 01-08-2016 | News

    Fesoterodine

    First report of delirium: case report
  7. 01-04-2009 | OriginalPaper

    Fesoterodine

    Fesoterodine is a muscarinic receptor antagonist that is rapidly and extensively converted to the active and more potent metabolite 5-hydroxymethyltolterodine. The drug is approved for once-daily oral administration in patients with overactive …

  8. 01-01-2013 | News

    Fesoterodine

    Gastrointestinal haemorrhage: 7 case reports
  9. 01-01-2013 | News

    Fesoterodine and GI bleeding, Vigibase search identifies signal

  10. 01-01-2010 | News

    Fesoterodine: a guide to its use in overactive bladder syndrome

    Overactive bladder syndrome (OAB) is a chronic and often debilitating condition that is characterized by symptoms of urinary urgency, with or without urinary incontinence, and is often accompanied by frequency and nocturia.[ 1 ] The prevalence of …

  11. 01-02-2019 | OriginalPaper

    Do patient characteristics predict which patients with overactive bladder benefit from a higher fesoterodine dose?

    Overactive bladder (OAB) symptoms, including urgency urinary incontinence (UUI), are prevalent and highly bothersome and negatively impact health-related quality of life [ 1 , 2 ]. Patients with OAB symptoms, including UUI, are more bothered by …

  12. 01-05-2014 | ReviewPaper

    Cost Effectiveness of Fesoterodine and Tolterodine for the Treatment of Overactive Bladder with Urge Urinary Incontinence in Spain and Finland

    As defined by the International Continence Society, overactive bladder (OAB) is a symptom-driven condition defined as urinary urgency, usually accompanied by frequency and nocturia, with or without urge incontinence [ 1 ]. The prevalence of OAB has …

  13. 01-10-2015 | ReviewPaper

    Treatment of Overactive Bladder in the Elderly Female: The Case for Trospium, Oxybutynin, Fesoterodine and Darifenacin

    Overactive bladder (OAB) is a common constellation of lower urinary tract storage symptoms that causes a significant impact on a person’s quality of life. The elderly may be disproportionally impacted by these symptoms due to concomitant poor …

  14. 01-07-2009 | OriginalPaper

    Efficacy and tolerability of fesoterodine in women with overactive bladder

    Overactive bladder (OAB) is prevalent in women, with a prevalence estimate of approximately 13% [ 1 ] in a large population-based study conducted in North America and in Europe. In addition to creating an economic burden [ 2 ], OAB symptoms …

  15. 01-10-2012 | ReviewPaper

    Fesoterodine in randomised clinical trials: an updated systematic clinical review of efficacy and safety

    Overactive bladder (OAB) is a medical syndrome of urinary storage symptoms defined as urgency with or without urge urinary incontinence (UUI) and is often associated with increased daytime frequency and nocturia [ 1 ]. The underlying pathology is …

  16. Open Access 01-12-2010 | OriginalPaper

    Modeling dose-response relationships of the effects of fesoterodine in patients with overactive bladder

    Fesoterodine is an antimuscarinic indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency [ 1 ]. The recommended starting dosage for fesoterodine is 4 mg once daily, which can be …

  17. 01-02-2012 | OriginalPaper

    Long-Term Safety, Tolerability and Efficacy of Fesoterodine in Subjects with Overactive Bladder Symptoms Stratified by Age

    Pooled Analysis of Two Open-Label Extension Studies

    Background: Previous work has demonstrated the efficacy and safety of fesoterodine in older and younger subjects with overactive bladder (OAB) symptoms. The effect of long-term fesoterodine treatment in different age groups has not been assessed.

  18. 01-06-2014 | OriginalPaper

    Effect of fesoterodine on urethral closure function in women with stress urinary incontinence assessed by urethral pressure reflectometry

    Urinary incontinence, or involuntary loss of urine, occurs when bladder pressure exceeds total urethral resistance, allowing urine to leak into the urethra [ 1 ]. Stress urinary incontinence (SUI) results from insufficient urethral closure pressure …

  19. 01-02-2015 | ReviewPaper

    Review of the Efficacy and Safety of Fesoterodine for Treating Overactive Bladder and Urgency Urinary Incontinence in Elderly Patients

    Overactive bladder (OAB) is a common condition, with prevalence rates increasing with advancing age. Symptoms of OAB, including urgency urinary incontinence (UUI), are associated with various co-morbidities in elderly individuals (e.g., falls and …

  20. 01-11-2012 | OriginalPaper

    Safety and efficacy of flexible-dose fesoterodine in British subjects with overactive bladder: insights into factors associated with dose escalation

    In the UK, the overall prevalence of overactive bladder (OAB) in adults is approximately 10 % and increases with advancing age [ 1 ]. The total economic burden of OAB on the National Health Service was estimated at greater than € 800 million in …

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