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Dermatomyositis and Polymyositis 

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  1. Open Access 01-12-2023 | Polymyositis | OriginalPaper

    Long-term secular trends in dermatomyositis and polymyositis mortality in the USA from 1981 to 2020 according to underlying and multiple cause of death mortality data

    Dermatomyositis (DM) and polymyositis (PM) are systemic inflammatory autoimmune myopathies affecting the skeletal muscles, skin, and other organs, with high morbidity and mortality [ 1 , 2 ]. According to a 2012 systemic review by Marie, the …

  2. 12-07-2022 | Polymyositis | ReviewPaper

    Physical exercise for dermatomyositis and polymyositis: a systematic review and meta-analysis

    Trials regarding physical exercise in dermatomyositis (DM) and polymyositis (PM) are heterogeneous. We aimed to summarize and critically analyze the available evidence to support the hypothesis that exercise is safe and improves strength and …

  3. 28-03-2024 | Juvenile Dermatomyositis | OriginalPaper

    Unveiling Cardiac Involvement in Juvenile Dermatomyositis Through Speckle-Tracking Echocardiography

    Early detection of cardiac involvement in Juvenile Dermatomyositis (JDM) is difficult due to the absence of clinical signs and symptoms, with systolic dysfunction often emerging in late stages and associated with a poor prognosis. This study aimed …

  4. Open Access 08-04-2024 | Respiratory Medicine | OriginalPaper

    A case of autoimmune pulmonary alveolar proteinosis during the course of treatment of rapidly progressive interstitial pneumonia associated with anti-MDA5 antibody-positive dermatomyositis

    Differentiating autoimmune pulmonary alveolar proteinosis (APAP) from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This case highlights the need for early APAP scrutiny.

  5. Open Access 05-03-2024 | Polymyositis | Online First

    Quantitative whole-body muscle MRI in idiopathic inflammatory myopathies including polymyositis with mitochondrial pathology: indications for a disease spectrum

    Idiopathic inflammatory myopathies (IIM) are rare and heterogeneous acquired autoimmune disorders. They present with a varying degree of muscular weakness, muscular inflammation, and a spectrum of extramuscular manifestations [ 1 , 2 ]. The current …

  6. 06-11-2023 | Dermatomyositis | OriginalPaper

    Low utilization of statins in patients with dermatomyositis/polymyositis and hyperlipidemia: a multicenter USA-based study (2013–2023)

    Despite the availability of multiple medications for the treatment of hyperlipidemia, HMG-CoA reductase inhibitors, more informally known as statins, remain a first-line therapy [ 1 ]. Statins are highly effective agents that have demonstrated …

  7. 05-07-2023 | Polymyositis | BriefCommunication

    Polymyositis/dermatomyositis readmissions: analysis of the nationwide readmission database

    Polymyositis and dermatomyositis (PM/DM) are idiopathic inflammatory myopathies characterized by subacute proximal limb weakness and inflammatory infiltration of skeletal muscles with or without distinctive skin rashes [ 1 , 2 ]. While polymyositis

  8. Open Access 01-12-2024 | Dermatomyositis | OriginalPaper

    Treatment strategies in MDA5-positive clinically amyopathic dermatomyositis: a single-center retrospective analysis

    Melanoma differentiation-associated protein 5 (MDA5) antibody positive amyopathic dermatomyositis (DM) is a rare inflammatory disease. So far, there is no official treatment guideline in MDA5 amyopathic dermatomyositis, but early and aggressive …

  9. 12-01-2023 | Laryngoscopy | OriginalPaper

    Dysphonia in Polymyositis/Dermatomyositis in Adults

    The purpose of this study was to examine clinical dysphonia in patients with polymyositis (PM)/dermatomyositis (DM). The subjects were 21 Japanese patients with PM/DM (11 females, 10 males; mean age ± SD, 61.4 ± 16.2 years) who visited our …

  10. 07-02-2024 | Dermatomyositis | OriginalPaper

    Clinical and immunological characteristics and prognosis of patients with autoantibody negative dermatomyositis: a case control study

    Idiopathic inflammatory myopathy (IIM) is a heterogeneous disease including dermatomyositis (DM), polymyositis, inclusion body myositis, immune-mediated necrotizing myopathy, and anti-synthetase antibody syndrome [ 1 ]. As one of the most common …

  11. Open Access 01-12-2024 | Dermatomyositis | OriginalPaper

    Safety and tolerability of intravenous immunoglobulin in patients with active dermatomyositis: results from the randomised, placebo-controlled ProDERM study

    Dermatomyositis is an idiopathic inflammatory myopathy characterised by rashes and progressive muscle weakness [ 1 ]. It is estimated to affect between 1 and 13 people per 100,000 of the US population [ 2 , 3 ]. Although the pathogenesis of …

  12. 31-07-2023 | Polymyositis | Erratum

    Correction to: Polymyositis/dermatomyositis readmissions: analysis of the nationwide readmission database

  13. 21-11-2023 | Dermatomyositis | OriginalPaper

    Gender differences in patients with anti-MDA5-positive dermatomyositis: a cohort study of 251 cases

    Dermatomyositis (DM) is a group of heterogeneous autoimmune diseases, mainly manifested by proximal muscle weakness and hallmark skin rash, often combined with interstitial lung disease (ILD), particularly rapidly progressive ILD (RPILD) [ 1 ].

  14. Open Access 14-06-2022 | Polymyositis | Erratum

    Correction to: Disease burden and treatment sequence of polymyositis and dermatomyositis patients in Japan: a real-world evidence study

  15. 14-03-2023 | Lung Cancer | OriginalPaper

    Anti-Mi-2 antibody-positive lung cancer-associated polymyositis

    After a 75-year-old man was diagnosed with lung cancer, proximal weakness and myalgia in the bilateral lower extremities developed, and the creatinine kinase (CK) level was elevated. The anti-Mi-2 antibody test was positive, muscle …

  16. 06-09-2023 | Dermatomyositis | Online First

    Nontuberculous mycobacterial myositis in dermatomyositis with long-term use of immunosuppressant: a case report

    Inflammatory myopathies, such as polymyositis and dermatomyositis, are systemic inflammatory disorders that affect skeletal muscles and internal organs. The treatment of inflammatory myopathies usually involves long-term use of high doses of …

  17. 03-10-2022 | Polymyositis | ReviewPaper

    Pneumomediastinum, pneumatosis intestinalis and pneumoperitoneum in a patient with polymyositis: case-based review

    Pneumomediastinum (PnM), pneumatosis intestinalis (PI), and pneumoperitoneum (PP) are rare complications of inflammatory myositis. We present a 59-year-old polymyositis (PM) patient who experienced all three complications simultaneously. The …

  18. 08-09-2023 | Dermatomyositis | Online First

    Successful management of interstitial lung disease in dermatomyositis complicated by malignancy: a case-based review

    Dermatomyositis (DM) is associated with interstitial lung disease (ILD) and malignancy. However, the coexistence of ILD and malignancy (DM–ILD–malignancy) is rare, and limited information exists regarding its management. Herein, we report the case …

  19. Association of various myositis-specific autoantibodies with dermatomyositis and polymyositis triggered by pregnancy

    Although pregnancy is an important risk factor for autoimmune rheumatic diseases, little is known regarding the association between pregnancy and dermatomyositis (DM) or polymyositis (PM). Herein, we present two patients with DM that developed …

  20. 25-08-2023 | Dermatomyositis | BriefCommunication

    Prominent mitochondrial pathology in a case of refractory dermatomyositis: coincidence or concause?

    Anti-Mi-2 antibody-positive dermatomyositis (DM) is an idiopathic inflammatory myopathy (IIM) with good treatment response and favorable outcome in most cases [ 1 ]. Very rarely, mitochondrial alterations on muscle biopsy have been reported in DM …

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