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Collagen 

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  1. Open Access 01-12-2024 | OriginalPaper

    Prognostic significance of collagen signatures in pancreatic ductal adenocarcinoma obtained from second-harmonic generation imaging

    Pancreatic cancer has a complex mechanism, high mortality rate, and an extremely poor prognosis [ 1 ]. Approximately 90% of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC) [ 2 ]. Its onset is insidious, and most patients are already …

  2. 01-04-2024 | News

    Collagenase

    Corporal rupture of the penis and haematoma
  3. 01-12-2024 | Glaucoma | OriginalPaper

    New suture probe canaloplasty combined with suprachoroidal collagen implantation

    Canaloplasty, as an effective non-penetrating surgical procedure for patients with progressive glaucoma has gained popularity over the past few years and has therefore replaced trabeculectomy in many operating rooms. The relatively gentle method …

  4. Open Access 30-05-2024 | Skin Wrinkling | Online First

    Beneficial Effects of Multi-Micronutrient Supplementation with Collagen Peptides on Global Wrinkles, Skin Elasticity and Appearance in Healthy Female Subjects

  5. Open Access 01-06-2024 | OriginalPaper

    Influence of an allogenic collagen scaffold on implant sites with thin supracrestal tissue height: a randomized clinical trial

    The establishment and maintenance of adequate peri-implant soft and hard tissue conditions are crucial for ensuring the long-term success of dental implants [ 1 ]. In addition to a sufficient bone bed, often referred to as the “bony envelope” [ 2 …

  6. Open Access 01-12-2024 | Gingiva Index | OriginalPaper

    A combination technique of strip free gingival grafts and xenogeneic collagen matrix in augmenting keratinized mucosa around dental implants: a single-arm clinical trial

    Nowadays, more research has focused on keratinized mucosa around dental implants, which has been considered to play a vital role in maintaining peri-implant health [ 1 ]. There is plenty of evidence that inadequate keratinized mucosa width (KMW) …

  7. Open Access 01-12-2024 | ReviewPaper

    Understanding the matrix: collagen modifications in tumors and their implications for immunotherapy

    Tumors are highly complex and heterogenous ecosystems where malignant cells interact with healthy cells and the surrounding extracellular matrix (ECM). Solid tumors contain large ECM deposits that can constitute up to 60% of the tumor mass. This …

  8. Open Access 23-04-2024 | Dupuytren Disease | OriginalPaper

    Long-term recurrence of Dupuytren’s disease treated with clostridium histolitycum collagenase. Surgical treatment and anatomopathological study

    Dupuytren’s disease (DD) is a progressive fibroproliferative disorder characterized by the development of collagen nodules and cords at the superficial palmar aponeurosis level that causes progressive finger closure [ 1 ].

  9. Open Access 10-05-2024 | Online First

    Recombinant Platelet-Derived Growth Factor-BB (rhPDGF-BB) Augmented Collagen Grafting for Oral Mucosal Defect Reconstruction

    Adequate reconstruction of surgical defects of the oral cavity following therapeutic or diagnostic resection of lesions is a challenging aspect of surgery. Reconstruction is affected by several factors. Collagen sheets have been used in previous …

  10. 02-02-2024 | Injectable Filler | ReviewPaper

    Ellansé: Advanced Technology and Advantageous Selection of New Collagen Stimulating Agents for Face Rejuvenation

    With the popularity of facial injection to reverse facial aging in China, according to the market statistics of China Cosmetics magazine, the market scale of hyaluronic acid cosmetics in China reached 68 billion yuan in 2020, of which the …

  11. 01-05-2024 | ReviewPaper

    Autogenous graft versus collagen matrices for peri-implant soft tissue augmentation. A systematic review and network meta-analysis*

    Soft tissue augmentation includes various surgical procedures that aim to functionally and aesthetically improve the morphology of soft tissues around teeth and implants: several surgical techniques allow the correction of gingival recessions, or …

  12. Open Access 01-12-2024 | Angiography | OriginalPaper

    Does collagen cross linking have any effect on retinal circulation in patients with keratoconus? An optical coherence tomography angiography (OCTA) study

    Keratoconus (KCN) is a non-inflammatory condition characterized by bilateral and gradual ectasia, leading to corneal thinning and bulging [ 1 ]. Clinical observations of KCN often reveal progressive myopia and irregular astigmatism [ 2 ]. The …

  13. 24-04-2024 | Alport Syndrome | Online First

    Trimerization profile of type IV collagen COL4A5 exon deletion in X-linked Alport syndrome

    Alport syndrome (AS) is a genetic disease characterized by progressive kidney dysfunction, hearing loss, and ocular abnormalities. AS is caused by a mutation in one of the type IV collagen genes, COL4A3 , COL4A4, and COL4A5 that encodes …

  14. Open Access 01-12-2024 | Smoking and Nicotine Detoxification | OriginalPaper

    Environmental tobacco smoke exposure exaggerates bleomycin-induced collagen overexpression during pulmonary fibrogenesis

    Environmental tobacco smoke (ETS) is known to cause lung inflammatory and injurious responses. Smoke exposure is associated with the pathobiology related to lung fibrosis, whereas the mechanism that ETS exposure augments pulmonary fibrogenesis is …

  15. 18-04-2024 | Online First

    Collagen and elastic fibers assessment of the human heart valves for age estimation in Thais using image analysis

    The study investigated the relationship between the histological compositions of the tricuspid, pulmonary, mitral, and aortic valves, and age. All 85 fresh human hearts were obtained with an age range between 20 and 90 years. The central area of …

  16. Open Access 08-11-2023 | ReviewPaper

    Epithelium-on versus epithelium-off corneal collagen crosslinking for keratoconus: a systematic review and meta-analysis

    Keratoconus derives from the Greek words ‘kéras,’ meaning cornea and ‘cõnus’ meaning cone, which together gives ‘cone-shaped’ cornea [ 1 ]. It is a bilateral asymmetric condition causing progressive corneal thinning and steepening and leading to …

  17. 27-03-2024 | Online First

    Type IV Collagen Promotes Adipogenic Differentiation of Adipose Stem Cells

    Type IV collagen is a major component of the extracellular matrix in adipose tissue. It is secreted during the lipogenic differentiation of mesenchymal stem cells, but its direct impact and mechanism on the differentiation of adipose-derived stem …

  18. Open Access 01-12-2024 | Erratum

    Correction: Enhanced molecular release from elderly bone samples using collagenase I: insights into fatty acid metabolism alterations

  19. Open Access 01-12-2024 | Cardiomyopathy | OriginalPaper

    HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy

    Dilated cardiomyopathy (DCM) is a progressive and debilitating cardiovascular disorder characterized by the enlargement of ventricular chambers and impaired systolic function. DCM is a leading cause of heart failure and results in notable …

  20. 15-03-2024 | OriginalPaper

    Evaluation of Collagenase Activity from Crab Hepatopancreas in Different Model Systems

    The effect of Kamchatka crab hepatopancreas containing three collagenolytic isoenzymes Collagenase KK and proteinases of Streptomyces lavendulae on metabolic activity and cell death were carried out on in vitro models. It was shown that changes in …

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