Cluster headache is a severe and debilitating neurological condition characterized by intense, excruciating pain with a significant impact on patients' wellbeing [ 1 ]. Patients suffering from cluster headache experience tremendously decreased …

Cluster headache is the most common trigeminal autonomic cephalalgia (TAC) with a prevalence of 1 in 1000 individuals [ 1 , 2 ]. Cluster headache involves a unilateral, usually retro-orbital, severe headache with ipsilateral autonomic features …

The Coronavirus disease swept rapidly throughout the world after its outbreak at the end of 2019 (Covid-19) [ 1 ]. To combat this pandemic, several targeted vaccines have been used globally with significant benefits in terms of reduced mortality …

Cluster headache (CH) is a primary headache disorder listed under the category of trigeminal autonomic cephalalgia (TAC), as defined by the International Classification Headache Disorders, 3rd edition (ICHD-3) [ 1 ]. CH is characterized by severe …

Four different trigeminal autonomic cephalalgies (TACs) are defined in the third edition of International Classification of Headache Disorders, all strict unilateral primary headaches associated with ipsilateral autonomic features [ 1 ]. Cluster …

Cluster headache (CH) is characterized by a distinctive pattern of cyclic recurrence of short-lasting unilateral excruciating craniofacial pain accompanied by trigeminal autonomic symptoms ipsilateral to the head pain such as rhinorrhea, eyelid …

Cluster headache is associated with a decreased quality of life (QoL) [ 1 ]. In recent years, there has been greater emphasis on patient-reported outcome measures (PROMs). In line with this development, the newly revised clinical trial guidelines …

Cluster headache (CH) is a primary headache disorder characterized by disabled trigeminal autonomic cephalalgia and severe unilateral headache lasting for 15–180 min [ 1 ]. The pain of CH attack is more severe than any other painful conditions and …

After the emergence of the COVID-19 pandemic, vaccination has become the most promising and effective weapon against the infection. Since then, vaccines against COVID-19 have played a major role in preventing the spread of the virus and reducing …

Cluster headache (CH) is the most common trigemino-autonomic cephalalgia [ 1 ]. The recurrent attacks up to 8 times per day are among the most severe pains described by humans, succeeding gun-shot wounds, giving birth and kidney stones [ 2 ]. The …

Cluster headache (CH) is a severe primary headache classified as a trigeminal autonomic cephalalgia [ 1 ]. Most patients with CH have bouts with daily headache attacks interspersed with symptom free periods (remission), this phenotype is labeled …

Cluster headache (CH) is a male-predominant [ 1 ], excruciating and strictly one-sided pain syndrome characterized by attacks accompanied by marked ipsilateral cranial autonomic symptoms, such as lacrimation and conjunctival injection [ 2 ]. CH …

Cluster headache belongs to the group of trigeminal autonomic headaches. This review summarizes drug therapy of cluster attacks and prophylactic treatment. Neurostimulation methods are not addressed. The therapy for acute cluster attacks includes …

Cluster headache (CH) is a primary trigeminal autonomic cephalalgia characterised by extremely grievous, strictly unilateral pain localized around the orbital, supraorbital or temporal areas. The headache attack lasts for 15 to 180 min and is …