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Bone Infection 

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  1. Open Access 01-12-2024 | Cryptococcosis | OriginalPaper

    Disseminated Cryptococcus neoformans infection involving multiple bones and lung in an immunocompetent patient: a case report

    Cryptococcosis stands as a noteworthy global opportunistic infection, predominantly impacting immunocompromised individuals, including patients with human immunodeficiency virus (HIV), organ transplant recipients, and those with malignancies [ 1 – …

  2. Open Access 01-12-2024 | External Fixator | OriginalPaper

    Treatment of tibial bone defects caused by infection: a retrospective comparative study of bone transport using a combined technique of unilateral external fixation over an intramedullary nail versus circular external fixation over an intramedullary nail

    The Ilizarov bone transport technique, which involves bone transport, is a commonly utilized method for treating bone defects resulting from various pathological conditions such as limb discrepancy, direct trauma, chronic osteomyelitis, and …

  3. Open Access 01-12-2024 | Joint Infection | OriginalPaper

    The burden of skin and soft tissue, bone and joint infections in an Australian cohort of people who inject drugs

    Injecting drug use (IDU) is a significant health issue in Australia, with a recent estimate indicating there are 118,000 PWID nationwide [ 1 ]. In 2022, the Australian Institute of Health and Welfare (AIHW) estimated that 1.5% of Australians over …

  4. 19-03-2024 | Joint Infection | Online First

    Disability-adjusted life years from bone and joint infections associated with antimicrobial resistance: an insight from the 2019 Global Burden of Disease Study

    Prosthetic joint infections [ 1 – 3 ] remain a significant concern because of the burgeoning challenge of antimicrobial resistance (AMR) [ 4 – 6 ], especially considering the growing number of joint replacement surgeries worldwide [ 7 ]. Despite …

  5. 01-04-2024 | Joint Infection | Online First

    Letter to the editor regarding the article “Disability-adjusted life years from bone and joint infections associated with antimicrobial resistance: an insight from the 2019 Global Burden of Disease Study”

  6. Open Access 01-12-2024 | External Fixator | OriginalPaper

    A unilateral external fixator combined with bone transport and tibio-talar fusion for the treatment of severe postoperative infection of peri-ankle fractures: retrospective analysis of 32 cases

    Fractures around the ankle joint are quite frequent among all bone fractures, representing approximately 10.2% of cases [ 1 ]. With the progress in transportation and construction industry, there has been an escalation in the occurrence of …

  7. 27-11-2023 | OriginalPaper

    Fracture related infection (FRI) of the upper extremity correlates with poor bone and soft tissue healing

    Fracture Related Infection (FRI) in upper extremity (UE) injuries are considered serious orthopedic complications following operative fixation. Fractures of the upper extremities are very common orthopedic injuries, yielding an annual incidence of …

  8. 13-09-2023 | Bone Defect | OriginalPaper

    The polymicrobial infection affects the infection recurrence rate (not failure) in treating femoral and tibial bone defects with the Masquelet technique—a comparative retrospective analysis of 54 patients with mono- and polymicrobial infections

    Infected segmental bone defects of the femur and tibia are among the most challenging scenarios for orthopedic trauma surgeons [ 1 ]. Due to its simplicity relative to other reconstruction alternatives, the Masquelet technique (MT) has gained …

  9. 21-12-2023 | Bone Infection | Online First

    Automatic detection, segmentation, and classification of primary bone tumors and bone infections using an ensemble multi-task deep learning framework on multi-parametric MRIs: a multi-center study

    Primary bone tumors (PBTs) represent a diverse group of rare tumors originating in the skeletal system, with the long bones most commonly affected [ 1 ]. PBTs more often occur in childhood and young adults and make up 5 to 6% of childhood …

  10. 03-05-2023 | Gentamicin | OriginalPaper

    Does antibiotic bone cement reduce infection rates in primary total knee arthroplasty?

    Periprosthetic joint infection (PJI) is one of the most severe and devastating complications following total joint arthroplasty (TJA) [ 1 ]. Despite an overall incidence of 2.0–2.4% in total hip arthroplasty (THA) and total knee arthroplasty (TKA) …

  11. 28-04-2023 | Artificial Intelligence | OriginalPaper

    An artificial intelligence framework for the diagnosis of prosthetic joint infection based on 99mTc-MDP dynamic bone scintigraphy

    The number of joint replacement procedures is increasing yearly; the number of primary total hip and knee arthroplasties (THA and TKA, respectively), as well as revision surgery in the USA, increased from 52,134 in 2012 to 2,224,587 in 2020 (TKA …

  12. Open Access 01-12-2023 | Bone Defect | OriginalPaper

    Complications associated with single-level bone transport for the treatment of tibial bone defects caused by fracture-related infection

    With the increasing familiarity of orthopaedic surgeons with distraction osteogenesis principles, the use of bone transport via a unilateral external fixator for the treatment of tibial bone defects caused by fracture-related infection (FRI) is …

  13. Open Access 11-08-2023 | Antibiotic | OriginalPaper

    Enhanced antibiotic release from bone cement spacers utilizing dual antibiotic loading with elevated vancomycin concentrations in two-stage revision for periprosthetic joint infection

    A periprosthetic joint infection (PJI) is one of the most serious complications after total joint replacement. According to the 2022 German Arthroplasty Registry Report (EPRD) it is the second most frequent reason for revision surgery [ 1 ]. The …

  14. Open Access 01-12-2023 | Vancomycin | Erratum

    Correction: Does local vancomycin powder impregnated with autogenous bone graft and bone substitute decrease the risk of deep surgical site infection in degenerative lumbar spine fusion surgery?—An ambispective study

  15. Open Access 01-12-2022 | Wound Infection | OriginalPaper

    The combined application of antibiotic-loaded bone cement and vacuum sealing drainage for sternal reconstruction in the treatment of deep sternal wound infection

    Deep sternal wound infection (DSWI) following cardiac surgery is a devastating complication with the need for subsequent surgical procedures, prolonged hospital stay and increased morbidity and mortality [ 1 – 3 ]. Its incidence is reported between …

  16. 09-05-2023 | Joint Infection | ReviewPaper

    Indications and techniques for non-articulating spacers in massive bone loss following prosthetic knee joint infection: a scoping review

    Knee replacement (KR) surgery is one of the most commonly performed musculoskeletal procedures and is highly successful at improving pain and function in patients with end-stage osteoarthritis refractory to non-surgical management [ 1 , 2 ]. Whilst …

  17. Open Access 01-02-2022 | Bone Infection | ReviewPaper

    Pathophysiology of Demineralization, Part II: Enamel White Spots, Cavitated Caries, and Bone Infection

    Demineralization is the fundamental mechanism for loss of mineralized tissue [ 1 – 5 ]. The biomechanics of routine loading, parafunction, and aging results in accumulation of microdamage that compromises structural integrity. Bone remodels to …

  18. 01-10-2021 | Clostridium

    Bone and joint infections caused by Clostridium perfringens: a case series

    The objective of this study was to evaluate antimicrobial therapy outcomes of bone and joint infections (BJI) caused by Clostridium perfringens. We investigated remission of symptoms and the absence of relapse or reinfection during follow-up.

  19. Open Access 01-12-2023 | Bone Defect | OriginalPaper

    Bifocal versus trifocal bone transport for the management of tibial bone defects caused by fracture-related infection: a meta-analysis

    Bone defects caused by fracture-related infection (FRI) remain challenging orthopaedic problems for surgeons [ 1 – 3 ]. Over the past decades, bone defects of the lower extremities have been successfully treated with several protocols, including …

  20. Open Access 02-05-2023 | Joint Infection | Report

    Real-Life Experience and Diagnostic Utility of the BioFire Joint Infection PCR Panel in Bone and Joint Infections: Analysis of a Prospective Validation Study

    Bone and joint infections (BJIs) are associated with considerable disability and substantial mortality [ 1 ]. Despite the need for prompt decision-making regarding antimicrobials and surgical intervention, BJIs often pose a clinical dilemma due to …

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