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327 search results for:

Azelastine 

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  1. Open Access 15-12-2023 | Azelastine | Erratum

    Correction: A Clinical Study to Assess the Efficacy and Safety of MP-AzeFlu Nasal Spray in Comparison to Commercially Available Azelastine Hydrochloride and Fluticasone Propionate Nasal Sprays in Chinese Volunteers with Allergic Rhinitis

  2. 05-06-2023 | Allergic Rhinitis | Letter

    Azelastine/fluticasone and allergic rhinitis in clinical practice

  3. Open Access 14-08-2023 | Fluticasone | OriginalPaper

    A Clinical Study to Assess the Efficacy and Safety of MP-AzeFlu Nasal Spray in Comparison to Commercially Available Azelastine Hydrochloride and Fluticasone Propionate Nasal Sprays in Chinese Volunteers with Allergic Rhinitis

    Allergic rhinitis is a major chronic respiratory disease due to its prevalence, impact on quality of life, impact on individual performance and productivity, economic burden, and links with asthma [ 1 ]. Allergic rhinitis (AR) affects 10–40% of the …

  4. 06-05-2023 | Allergic Rhinitis | OriginalPaper

    Fluticasone Propionate with Azelastine Versus Standalone Fluticasone Propionate as Nasal Spray in Allergic Rhinitis: A Prospective Comparative Study in a Rural Population of Northern India

    Background: Allergic rhinitis (AR) is a symptomatic condition of the nose, caused by an IgE-mediated inflammation of the nasal membranes. Allergic rhinitis is further split into two categories, based on the duration of symptoms: intermittent (IAR) …

  5. 02-08-2021 | Allergic Rhinitis | OriginalPaper

    Comparison of the Effects of Azelastine and Fluticasone Nasal Sprays in the Treatment of Allergic Rhinitis

    Allergic rhinitis is a highly prevalent, allergen-induced disease. Intranasal corticosteroids are currently the first-line therapy for these patients. It is uncertain whether intranasal antihistamines have comparable efficacy. This study compares …

  6. 01-03-2012 | Abstract

    Azelastine

    Exacerbation of rhinoconjunctivitis: case report
  7. 01-02-2012 | Abstract

    Azelastine/naproxen

    Oesophageal intramural dissection?: case report
  8. 01-09-2010 | Abstract

    Azelastine/emedastine/hydroxyzine

    Chorea (first report) in an elderly patient: case report
  9. 01-04-2005 | Abstract

    Azelastine

    First report of hypertension following intranasal administration: case report
  10. 01-07-1998 | OriginalPaper

    Intranasal Azelastine

    A Review of its Efficacy in the Management of Allergic Rhinitis

    Conclusion: Twice-daily intranasal azelastine offers an effective and well tolerated alternative to other antihistamine agents currently recommended for the symptomatic relief of mild to severe SAR and PAR in adults and children (aged ≥12 years in …

  11. 01-12-2015 | OriginalPaper

    Azelastine hydrochloride/fluticasone propionate combined in a single nasal spray: a guide to its use in allergic rhinitis

    Azelastine hydrochloride/fluticasone propionate 137/50 μg nasal spray (henceforth MP-AzeFlu) [Dymista®] provides a combination of two first-line treatments for allergic rhinitis, an intranasal antihistamine and an intranasal corticosteroid, in a …

  12. Open Access 01-12-2018 | OriginalPaper

    Superior effect of MP-AzeFlu than azelastine or fluticasone propionate alone on reducing inflammatory markers

    Allergic rhinitis (AR) is one of the most common chronic diseases, impairing quality of life and causing billions of dollars of lost productivity annually [ 1 ]. AR is characterized by upper airway inflammation, sneezing, and nasal congestion …

  13. 01-03-2014 | OriginalPaper

    A clinical pharmacokinetic study comparing two azelastine hydrochloride nasal formulations in a single-dose design

    Azelastine hydrochloride is a potent second-generation antihistamine, available in Europe and the USA as a nasal spray formulation for the treatment of allergic rhinitis symptoms. GlaxoSmithKline (GSK) Consumer Healthcare has developed a new nasal …

  14. 01-02-2017 | OriginalPaper

    Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells

    Both glucocorticoids and H1-antihistamines are widely used on patients with airway diseases. However, their direct effects on airway epithelial cells are not fully explored. Therefore, we use the primary culture of human nasal epithelial cells …

  15. 01-07-1998 | News

    Azelastine

  16. 01-07-2004 | OriginalPaper

    Ocular allergy treatment comparisons: Azelastine and olopatadine

    Azelastine hydrochloride 0.05% and olopatadine hydrochloride 0.1% are topical ocular allergy treatments that have demonstrated multiple pharmacologic actions, including antihistamine, mast cell stabilization, and inhibition of proinflammatory …

  17. 01-05-2015 | OriginalPaper

    Azelastine enhances the clinical efficacy of glucocorticoid by modulating MKP-1 expression in allergic rhinitis

    Azelastine was suggested as a supplementary choice of glucocorticoid for the control of moderate to severe allergic rhinitis (AR). However, the underlying mechanism has not been completely understood. In this study, primary cultured nasal …

  18. 01-05-1997 | OriginalPaper

    A placebo controlled study comparing the efficacy of intranasal azelastine and beclomethasone in the treatment of seasonal allergic rhinitis

    This study compared a new intranasal anti-allergic drug, azelastine (0.56 mg bid) with intranasal beclomethasone (0.2 mg bid) and placebo in the treatment of symptoms associated with seasonal rhinitis. After administering placebo for 3–5 days as a …

  19. Open Access 01-07-2013 | Abstract

    Azelastine hydrochloride and budesonide (nasal sprays): effectiveness combination therapy monitored by acoustic rhinometry and clinical symptom score in the treatment of allergic rhinitis

    Guidelines therapy for allergic rhinitis (AR) recommends new-generation H1-antihistamines and intranasal corticosteroids as main treatment. The objective for this study was to evaluate the effects of intranasal therapy with azelastine

  20. Open Access 01-12-2013 | OriginalPaper

    A four-way, double-blind, randomized, placebo controlled study to determine the efficacy and speed of azelastine nasal spray, versus loratadine, and cetirizine in adult subjects with allergen-induced seasonal allergic rhinitis

    Seasonal allergic rhinitis (SAR) is an inflammatory disease characterized by multiple symptoms including sneezing, rhinnorhea, nasal congestion, nasal and nasopharyngeal itching, and has associated ocular symptoms such as itchy, watery and …

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