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Anti-Infective Prophylaxis 

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  1. 20-12-2023 | Endocarditis | Review

    Infective Endocarditis Antibiotic Prophylaxis: Review of the Evidence and Guidelines

    Antibiotic prophylaxis and its role in prevention of infective endocarditis is controversial, with international societies offering conflicting advice. This review summarises the various guidelines and the evidence underpinning their recommendations. 

  2. 01-12-2020 | Streptococci | Original Research

    Investigation of the impact of the NICE guidelines regarding antibiotic prophylaxis during invasive dental procedures on the incidence of infective endocarditis in England: an electronic health records study

    Infective endocarditis is an uncommon but serious infection, for which the evidence for giving antibiotic prophylaxis to people undergoing invasive dental procedures is inconclusive. In March 2008, the National Institute for Health and Care …

  3. Open Access 16-08-2022 | Antibiotic | ReviewPaper

    Antibiotic prophylaxis before dental procedures to prevent infective endocarditis: a systematic review

    Infective endocarditis (IE) is a severe bacterial infection of the heart valves that often occurs on congenitally malformed or degenerated cardiac valves with or without dysfunction [ 1 ]. Due to the high mortality rate of up to 30%, the disease …

  4. 01-10-2020 | Pulmonary Valve Replacement | OriginalPaper

    Time-trend population analysis of the clinical and epidemiologic effect on pediatric infective endocarditis after change of antibiotic prophylaxis guidelines

    Infective endocarditis (IE) is a rare but severe bacterial infection affecting the valvar and mural endocardium, or the endothelium of the great vessels surrounding the heart [ 1 ]. In childhood, IE is linked with congenital heart defect (CHD) as …

  5. 01-10-2020 | Antibiotic | Erratum

    Correction to: Time‑trend population analysis of the clinical and epidemiologic effect on pediatric infective endocarditis after change of antibiotic prophylaxis guidelines

    The original version of this article unfortunately contained a mistake. In the author list, the first and last names were tagged incorrectly. The corrected author list is given above.

  6. 01-08-1998 | News

    Infective endocarditis: antibacterial prophylaxis considered important

  7. Open Access 01-02-2017 | ReviewPaper

    Antibiotic Prophylaxis of Infective Endocarditis

    Links between infective endocarditis (IE) and dental and other invasive procedures were first identified in the 1920s, and the use of antibiotic prophylaxis (AP) to prevent IE was first recommended by the American Heart Association in 1955.

  8. 01-09-2000 | OriginalPaper

    Practice parameters for antibiotic prophylaxis to prevent infective endocarditis or infected prosthesis during colon and rectal endoscopy

  9. 01-06-2001 | Letter

    Practice parameters for antibiotic prophylaxis to prevent infective endocarditis or infected prosthesis during colon and rectal endoscopy

  10. 01-07-2006 | Report

    Infective endocarditis complicating rituximab (anti-CD20 monoclonal antibody) treatment in an SLE patient with a past history of Libman–Sacks endocarditis: a case for antibiotic prophylaxis?

    We report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by Libman-Sacks endocarditis more than 20 years previously.

  11. 16-02-2024 | Nosocomial Pneumonia | News | Article

    Short-course antibiotics equal to usual care in VAP

    Use of short courses of antibiotics in adults with ventilator-associated pneumonia does not increase their risk for death or recurrence versus standard prolonged treatment.

  12. 09-02-2024 | Nosocomial Pneumonia | News | Article

    Prophylactic antibiotic reduces ventilator-associated pneumonia risk

    He comments: “If further studies confirm benefits without harm in patients with acute brain injuries, this might be the ICU subpopulation in whom we can begin to use antibiotic prophylaxis more broadly and therein advance our collective experience, understanding, and comfort level with this controversial but potentially life-saving prevention strategy.” medwireNews is an independent medical news service provided by Springer  Healthcare Ltd. © 2024 Springer Healthcare Ltd, part of the Springer Nature Group Lancet Respir Med 2024; doi:10.1016/ S2213-2600(23)00471-X  Lancet Respir Med 2024; doi:10.1016/ S2213-2600(24)00006-7 

  13. 02-02-2024 | Hematologic Cancer | News | Article

    Tixagevimab–cilgavimab supported for COVID-19 prophylaxis in hematologic cancer patients

    A cohort study suggests that the prophylactic use of tixagevimab–cilgavimab may reduce the incidence and severity of COVID-19 in patients with hematologic cancers.

  14. 30-01-2024 | Shingles | News | Article

    Two doses of recombinant vaccine effective against herpes zoster for 4 years

    Two doses of the recombinant zoster vaccine are 76% effective at protecting against incident herpes zoster, with the level of protection largely maintained over a 4-year period.

  15. 05-01-2024 | Respiratory Syncytial Virus Infection | News | Article

    RSV vaccine efficacious in older people

    An mRNA-based vaccine against the respiratory syncytial virus significantly reduces the incidence of associated lower respiratory tract disease in the over 60s.

  16. 18-01-2024 | Influenza | News | Article

    Maternal vaccination significantly reduces influenza risk in infants

    Maternal vaccination reduces the likelihood of medically attended influenza illness by a third in infants younger than 6 months, with maximum effectiveness in those born to mothers vaccinated during the third trimester.

  17. 11-01-2024 | Influenza | News | Article

    Recombinant flu vaccine offers greater protection than standard vaccine in older adults

    Quadrivalent recombinant influenza vaccine is significantly more effective than standard-dose vaccine at preventing the virus in adults aged 50 to 64 years.

  18. Open Access 02-05-2024 | Lymphoma | Online First

    Economic evaluation of anti-CD19 CAR T-cell pathway for large B-cell lymphomas in the real-life setting: the experience of an Italian hub center in the first three years of activity

    Poor literature report actual and detailed costs of chimeric antigen receptor (CAR) T-cell pathway in a real-life setting. We retrospectively collect data for all patients with relapsed/refractory aggressive large B-cell lymphoma who underwent …

  19. 10-05-2023 | Case-Based Insights: Oncology and Hematology | Training Course | Course

    32/♀ with planned induction therapy for newly diagnosed acute lymphocytic leukaemia – Case 5

    After obtaining all the necessary findings, you diagnose a 32-year-old female patient with Philadelphia-negative common ALL. Then you initiate induction therapy in conformity with the GMALL protocol. What do you have to consider, and what could the strategy for anti-infective prophylaxis look like here?

  20. 26-09-2023 | Vesicoureteral Reflux in Pediatrics | News | Article

    Antibiotic prophylaxis prevents UTIs in infants with vesicoureteral reflux but at what cost?

    PREDICT trial results show antibiotic prophylaxis may prevent urinary tract infections among some infants with vesicoureteral reflux, but routine use is unlikely to be beneficial.

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