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Addison's Disease 

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  1. 09-02-2024 | Addison's Disease | OriginalPaper

    Predictors of bone mineral density in patients receiving glucocorticoid replacement for Addison’s disease

    Patients with primary adrenal insufficiency (Addison’s disease, AD) require lifelong glucocorticoid (GC) replacement for their survival. According to the current recommendations, monitoring of steroid replacement is primarily based upon regular …

  2. Open Access 01-12-2023 | Tuberculosis | OriginalPaper

    Coronary artery disease in a patient with Addison’s disease: a case report and literature review

    Primary adrenal insufficiency (PAI), known as Addison’s disease, was first reported by Thomas Addison in 1855 [ 1 ]. The prevalence is about 10–15 cases per 100,000 [ 2 ]. The main cause of Addison’s disease in developed countries is autoimmune …

  3. 01-03-2023 | Hyperpigmentation | ReviewPaper

    Addison’s disease without hyperpigmentation in pediatrics: pointing towards specific causes

    Hyperpigmentation of mucous membranes and skin, particularly in the axillae, nipples, palmar creases, sun-exposed areas, and other pressure points, has always been considered a basic manifestation of Addison’s disease. The cause of skin …

  4. Open Access 01-12-2022 | Tuberculosis | OriginalPaper

    Addison’s disease triggered by infection with mycobacterium abscessus, but not by adrenal tuberculosis or MAC pulmonary disease, in a subject with type 2 diabetes mellitus: case report

    Addison’s disease is primary adrenal dysfunction and is characterized by marked decrease of cortisol level accompanied by increase of adrenocorticotropic hormone (ACTH) level. Hyponatremia, hypoglycemia and hypotension are often observed in …

  5. 01-06-2022 | Autopsy

    Regarding “Fatal adrenal crisis due to Addison’s disease arising in the context of autoimmune polyglandular syndrome type 1”

  6. Open Access 01-12-2021 | Tuberculosis | OriginalPaper

    Addison’s disease associated with hypokalemia: a case report

    Addison’s disease may manifest with electrolyte abnormalities, metabolic derangements, and associated endocrinopathies, some of which are reversible by replacement with glucocorticoids and mineralocorticoids alone. The clinical features of primary …

  7. 01-06-2022 | Addison's Disease | Erratum

    Author Correction: Regarding “Fatal adrenal crisis due to Addison’s disease arising in the context of autoimmune polyglandular syndrome type 1”

  8. 01-12-2019 | Addison's Disease | ReviewPaper

    Epidemiology, pathogenesis, and diagnosis of Addison’s disease in adults

    In 1563 one of the greatest anatomist of the Renaissance period, Bartolomeo Eustachius described the adrenals for the first time as “ de glandulis quae renibus incumbunt ” [ 1 ]. Three hundred years later, in 1855, Thomas Addison at Guy’s Hospital …

  9. 01-03-2020 | Addison's Disease | OriginalPaper

    Fatal adrenal crisis due to Addison’s disease arising in the context of autoimmune polyglandular syndrome type 1

    The autoimmune polyglandular syndromes (APS) are rare immune-mediated endocrinopathies causing destruction of multiple endocrine and non-endocrine organs. Involvement of adrenal glands associated with any type of APS results in Addison’s disease.

  10. Open Access 01-12-2021 | Tuberculosis | OriginalPaper

    An autopsy case of unexpected death due to Addison’s disease caused by adrenal tuberculosis

    Thomas Addison first described the clinical presentation of primary adrenocortical insufficiency in 1855 and Trousseau defined an adrenal insufficiency as an Addison’s disease (AD) in 1856 [ 1 , 2 ]. Adrenal insufficiency (AD) continues to present …

  11. Open Access 01-12-2022 | Magnetic Resonance Imaging | OriginalPaper

    Repeatability assessment of sodium (23Na) MRI at 7.0 T in healthy human calf muscle and preliminary results on tissue sodium concentrations in subjects with Addison’s disease

    Over the last two decades, clinical research has demonstrated that biochemical information on disease progression and treatment efficacy may be obtained with a non-invasive metabolic imaging modality called sodium magnetic resonance imaging ( 23 …

  12. 01-01-2020 | Hypercalcemia | ReviewPaper

    Renal involvement in adrenal insufficiency (Addison disease): can we always recognize it?

    Addison disease is due to the destruction or dysfunction of the entire adrenal cortex. Nowadays, the causes of adrenal insufficiency are autoimmune disease for 70–90% and tuberculosis for 7–20%. Many typical signs and symptoms, such as …

  13. 01-06-2020 | Addison's Disease | ReviewPaper

    Primary antiphospholipid syndrome, Addison disease, and adrenal incidentaloma

    Primary adrenal failure comprises an insufficient production of mineralocorticoids and glucocorticoids in the adrenal cortex. A rare manifestation of antiphospholipid syndrome (APS) is adrenal failure. The majority of patients with adrenal …

  14. 01-05-2016 | OriginalPaper

    The acute effect of a mineralocorticoid receptor agonist on corticotrope secretion in Addison’s disease

    The hypothalamic–pituitary–adrenal (HPA) axis is mainly regulated by the neurohormones corticotrophin-releasing hormone (CRH) and arginine vasopressin (AVP), which, in turn, are under the influence of several neurotransmitters and neuropeptides [ 1 …,

  15. 01-04-2001 | Letter

    White Addison’s disease: An intrinsic cellular defect

  16. 01-05-1999 | OriginalPaper

    White Addison’s disease: What is the possible cause?

    A case of chronic primary adrenal insufficiency without hyperpigmentation in a 64-yearold woman is reported. Due to the absence of hyperpigmentation the diagnosis was delayed and she became critically ill. During endocrine evaluation, in order to …

  17. 01-10-2011 | Letter

    Subclinical Addison’s disease mimicking a silent corticotroph adenoma

  18. 01-07-2003 | ReviewPaper

    Diagnosis and management of Addison’s disease during pregnancy

    Although primary adrenal failure is considered a rare condition, recent epidemiological studies indicate a rising incidence of the disease owing to the increase of autoimmune disorders. Addison’s disease may be a life-threatening condition and the …

  19. 01-03-2010 | Letter

    Severe rhabdomyolysis as a first symptom in Addison’s disease

  20. 01-05-1999 | OriginalPaper

    Unusual association of thyroiditis, Addison’s disease, ovarian failure and celiac disease in a young woman

    The coexistence of autoimmune endocrine diseases, particularly autoimmune thyroid disease and celiac disease (CD), has recently been reported. We here present a 23-year-old woman with a diagnosis of hypothyroidism due to Hashimoto’s thyroiditis …

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