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01-12-2005 | Case Report

Tophaceous gout in the cervical spine

Authors: Jonathan Cabot, Leigh Mosel, Andrew Kong, Mike Hayward

Published in: Skeletal Radiology | Issue 12/2005

Abstract

Gout is a common metabolic disorder typically affecting the distal joints of the appendicular skeleton. Involvement of the axial skeleton, particularly the facet joints and posterior column of the cervical spine, is rare. This case report highlights such a presentation in a 76-year old female who presented with cervical spine pain following a fall. Her radiological findings were suggestive of a destructive metastatic process. Histological diagnosis confirmed tophaceous gout.

Kim K, Schumacher H, Hunsche E, et al. A literature review of the epidemiology and treatment of acute gout. Clin Ther 2003; 25(6):1593–617

Terkeltaub R. Gout. N Engl J Med 2003; 349:1647–1655.CrossRefPubMed

Cotran R, Kumar V, Collins T. Robbins pathologic basis of disease, 6th edn. Philadelphia: WB Saunders, 1999.

Duprez T, Malghem J, Vande Berg B, et al. Gout in the cervical spine: MR pattern mimicking discovertebral infection. Am J Neuroradiol 1996; 17(1):151–153.

Vinstein A, Cockerill E. Involvement of the spine in gout. Radiology 1972; 103(2): 311–312.

Diaz A, Porhiel V, Sabatier P, et al. Tophaceous gout of the cervical spine, causing cord compression. Case report and review of literature. Neurochirurgie 2003; 49(6):600–604.

Alarcon G, Reveille J. Gouty arthritis of the axial skeleton including the sacroiliac joints. Arch Intern Med 1987; 147(11):2018–2019.

Magid S, Gray G, Amand A. Spinal cord compression by tophi in patient with chronic polyarthritis. Arthritis Rheum 1981; 24:1431–1434.PubMedCrossRef

Lichtenstein L, Scott H, Levin M. Pathologic changes in gout: survey of eleven necropsied cases. Am J Pathol 1956; 32:871–895.PubMed

10.

Hall M, Selin G. Spinal involvement in gout. J Bone Joint Surg 1960;42:341–343.

11.

Tkach S. Gouty arthritis of the spine. Clin Orthop 1970; 71:81–86.PubMed

12.

Resnick, D. Gouty Arthritis. In: Resnick D, ed. Diagnosis of bone and joint disorders, 4th edn. Philadelphia: Saunders, 2002:1519–1560.

13.

Alcalay M, Goupy M, Azais I, Bontoux D. Hemodialysis is not essential for the development of destructive spondylarthropathy in patients with chronic renal failure. Arthritis Rheum 1987; 30(10):1182–1186.

14.

Aaron S, Miller J, Percy J. Tophaceous gout in the cervical spine. J Rheumatol 1984; 11(6):862–865.

15.

Snaith M. ABC of Rheumatology: gout, hyperuricaemia and crystal arthritis. BMJ 1995; 310:521–524.PubMed

16.

Emmerson B. The management of gout. N Engl J Med 1996; 334:445–451.CrossRefPubMed

Title: Tophaceous gout in the cervical spine
Authors: Jonathan Cabot
Leigh Mosel
Andrew Kong
Mike Hayward
Publication date: 01-12-2005
Publisher: Springer-Verlag
Published in: Skeletal Radiology / Issue 12/2005
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-005-0920-0

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Tophaceous gout in the cervical spine

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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