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01-03-2021 | Tooth Extraction | Original Article

Development of osteomyelitis following dental abscesses—influence of therapy and comorbidities

Authors: Julius Moratin, Christian Freudlsperger, Karl Metzger, Caroline Braß, Moritz Berger, Michael Engel, Jürgen Hoffmann, Oliver Ristow

Published in: Clinical Oral Investigations | Issue 3/2021

Abstract

Objectives

Bacterial osteomyelitis of the jaw is a severe disease potentially requiring extensive surgical treatment. We have evaluated the incidence rates of bacterial osteomyelitis following dental abscessation associated with primary or secondary tooth extraction.

Materials and methods

A retrospective cohort study was designed and included patients with dental abscesses and surgical treatment including the extraction of focus teeth. Patients were either treated with primary removal during acute infection or secondary delayed extraction within an infection-free interval. The primary outcome variable was the occurrence of bacterial osteomyelitis following the abscess. Secondary outcomes were the influence of general disease, antibiotic therapy, and surgical technique.

Results

One hundred nine patients were enrolled in the study; 4 patients (3.7%) developed osteomyelitis. Primary tooth extraction was performed on all these patients (p = 0.017). Significant associations of diabetes (p = 0.001), the use of clindamycin (p = 0.025), and transcutaneous incision (p = 0.017) with the incidence of osteomyelitis were detected.

Conclusions

More severe infections may be associated with a higher risk for the development of osteomyelitis following dental abscesses. A history of diabetes and clindamycin therapy might form further predisposing risk factors. Because of the low incidence and the small case number, our data need to be interpreted carefully.

Clinical relevance

Osteomyelitis of the jaw is a rare but severe disease that may require extensive therapy and that impairs the quality of life of affected patients. The evaluation of risk factors to enable further reduction of incidence is therefore urgently required.

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Title: Development of osteomyelitis following dental abscesses—influence of therapy and comorbidities
Authors: Julius Moratin
Christian Freudlsperger
Karl Metzger
Caroline Braß
Moritz Berger
Michael Engel
Jürgen Hoffmann
Oliver Ristow
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Keywords: Tooth Extraction
Antibiotic
Tooth Extraction
Clindamycin
Incision
Osteomyelitis
Published in: Clinical Oral Investigations / Issue 3/2021
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-020-03447-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Development of osteomyelitis following dental abscesses—influence of therapy and comorbidities

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

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