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go back to reference Bruzzone A, Sauliere A, Finana F, Senard JM, Luthy I, Gales C (2014) Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals. FASEB J 28:1342–1354. doi:10.1096/fj.13-239285 CrossRefPubMed Bruzzone A, Sauliere A, Finana F, Senard JM, Luthy I, Gales C (2014) Dosage-dependent regulation of cell proliferation and adhesion through dual β2-adrenergic receptor/cAMP signals. FASEB J 28:1342–1354. doi:10.​1096/​fj.​13-239285 CrossRefPubMed
go back to reference Carie AE, Sebti SM (2007) A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway. Oncogene 26:3777–3788. doi:10.1038/sj.onc.1210172 CrossRefPubMed Carie AE, Sebti SM (2007) A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway. Oncogene 26:3777–3788. doi:10.​1038/​sj.​onc.​1210172 CrossRefPubMed
go back to reference Chen TC, Hinton DR, Zidovetzki R, Hofman FM (1998) Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. Lab Invest 78:165–174PubMed Chen TC, Hinton DR, Zidovetzki R, Hofman FM (1998) Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. Lab Invest 78:165–174PubMed
go back to reference Coelho M, Soares-Silva C, Brandao D, Marino F, Cosentino M, Ribeiro L (2017) β-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectives. J Cancer Res Clin Oncol 143:275–291 doi:10.1007/s00432-016-2278-1 CrossRefPubMed Coelho M, Soares-Silva C, Brandao D, Marino F, Cosentino M, Ribeiro L (2017) β-Adrenergic modulation of cancer cell proliferation: available evidence and clinical perspectives. J Cancer Res Clin Oncol 143:275–291 doi:10.​1007/​s00432-016-2278-1 CrossRefPubMed
go back to reference Gargiulo L et al (2014) Differential beta(2)-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines. Oncotarget 5:10058–10069CrossRefPubMedPubMedCentral Gargiulo L et al (2014) Differential beta(2)-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines. Oncotarget 5:10058–10069CrossRefPubMedPubMedCentral
go back to reference Hilal-Dandan R, Knollman B, Brunton L (2017) Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 13th Edition. McGraw-Hill Education Hilal-Dandan R, Knollman B, Brunton L (2017) Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 13th Edition. McGraw-Hill Education
go back to reference Skalhegg BS, Tasken K (2000) Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA. Front Biosci J Virtual Library 5:D678–D693 Skalhegg BS, Tasken K (2000) Specificity in the cAMP/PKA signaling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA. Front Biosci J Virtual Library 5:D678–D693
go back to reference Strell C, Niggemann B, Voss MJ, Powe DG, Zanker KS, Entschladen F (2012) Norepinephrine promotes the beta1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROalpha release. Mol Cancer Res MCR 10:197–207. doi:10.1158/1541-7786.MCR-11-0130 CrossRefPubMed Strell C, Niggemann B, Voss MJ, Powe DG, Zanker KS, Entschladen F (2012) Norepinephrine promotes the beta1-integrin-mediated adhesion of MDA-MB-231 cells to vascular endothelium by the induction of a GROalpha release. Mol Cancer Res MCR 10:197–207. doi:10.​1158/​1541-7786.​MCR-11-0130 CrossRefPubMed
go back to reference Sullivan KG, Levin M (2016) Neurotransmitter signaling pathways required for normal development in Xenopus laevis embryos: a pharmacological survey screen. J Anatomy 229:483–502 doi:10.1111/joa.12467 CrossRef Sullivan KG, Levin M (2016) Neurotransmitter signaling pathways required for normal development in Xenopus laevis embryos: a pharmacological survey screen. J Anatomy 229:483–502 doi:10.​1111/​joa.​12467 CrossRef
Metadata
Title
To block it, or not to block it?
Author
Artur Wnorowski
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Journal of Cancer Research and Clinical Oncology / Issue 12/2017
Print ISSN: 0171-5216
Electronic ISSN: 1432-1335
DOI
https://doi.org/10.1007/s00432-017-2400-z

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