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Critical Care
Published in: Critical Care 1/2009

01-02-2009 | Letter

Timeliness of administration of vasopressors in CPR

Authors: Stefek Grmec, Stefan Mally

Published in: Critical Care | Issue 1/2009

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Excerpt

We read with great interest the report by Gueugniaud and coworkers [1] on the role of combined vasopressin and epinephrine during advanced cardiac life support for out-of-hospital cardiac arrest. The authors conclude that the combination does not improve outcome. In some of our previous studies [2, 3] we identified improvements in restoration of spontaneous circulation (ROSC) and/or survival and neurological outcome when combining vasopressors to manage out-of-hospital cardiac arrest, and therefore we were surprised by the results of this study. …
Literature
1.
Gueugniaud PY, David JS, Chanzy E, Hubert H, Dubien PY, Mauriaucourt P, Bragança C, Billères X, Clotteau-Lambert MP, Fuster P, Thiercelin D, Debaty G, Ricard-Hibon A, Roux P, Espesson C, Querellou E, Ducros L, Ecollan P, Halbout L, Savary D, Guillaumée F, Maupoint R, Capelle P, Bracq C, Dreyfus P, Nouguier P, Gache A, Meurisse C, Boulanger B, Lae C, et al.: Vasopressin and epinephrine vs. epinephrine alone in cardiopulmonary resuscitation. N Engl J Med 2008, 359: 21-30. 10.1056/NEJMoa0706873CrossRefPubMed
2.
Mally S, Jelatancev A, Grmec S: Effects of epinephrine and vasopressin on end-tidal carbon dioxide tension and mean arterial blood pressure in out-of-hospital cardiopulmonary resuscitation: an observational study. Crit Care 2007, 11: R39. 10.1186/cc5726PubMedCentralCrossRefPubMed
3.
Grmec S, Mally S: Vasopressin improves outcome in out-of-hospital cardiopulmonary resuscitation of ventricular fibrillation and pulseless ventricular tachycardia: a observational study. Crit Care 2006, 10: R13. 10.1186/cc3967PubMedCentralCrossRefPubMed
Metadata
Title
Timeliness of administration of vasopressors in CPR
Authors
Stefek Grmec
Stefan Mally
Publication date
01-02-2009
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2009
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc7691

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