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Published in: Drugs 18/2005

01-12-2005 | Adis Drug Profile

Tigecycline

A Viewpoint by Ethan Rubinstein

Author: Ethan Rubinstein

Published in: Drugs | Issue 18/2005

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Excerpt

Skin and skin structure infections (SSSIs) account for 7–10% of hospitalisations in North America.[1] The increased prevalence of patients with diabetes mellitus, coupled with their considerable longevity, has led to a dramatic increase in the incidence of diabetic foot infections, frequently of polymicrobial nature.[2] In addition, the rapid worldwide spread of community-acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) strains causing SSSIs in children and adults has initiated a shift in the treatment paradigm of such infections.[3] …
Literature
1.
Vinh DC, Embil JM. Rapidly progressive soft tissue infections. Lancet Infect Dis 2005 Aug; 5(8): 501–13PubMedCrossRef
2.
Lipsky BA, Berendt AR, Deery HG, et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis 2004 Oct 1; 39(7): 885–910PubMedCrossRef
3.
Kaplan SL, Hulten KG, Gonzalez BE, et al. Three-year surveillance of community-acquired Staphylococcus aureus infections in children. Clin Infect Dis 2005 Jun 15; 40(12): 1785–91PubMedCrossRef
4.
Ellis-Grosse EJ, Babinchak T, Dartois N, et al. The efficacy and safety of tigecycline in the treatment of skin and skin structure infections: results of 2 double-blind phase 3 comparisons studies with vancomycin-aztreonam. Clin Infect Dis 2005; 41 Suppl. 5: S341–53PubMedCrossRef
Metadata
Title
Tigecycline
A Viewpoint by Ethan Rubinstein
Author
Ethan Rubinstein
Publication date
01-12-2005
Publisher
Springer International Publishing
Published in
Drugs / Issue 18/2005
Print ISSN: 0012-6667
Electronic ISSN: 1179-1950
DOI
https://doi.org/10.2165/00003495-200565180-00009

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