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Published in: Cardiology and Therapy 2/2020

Open Access 01-12-2020 | Ticagrelor | Review

Dual Antiplatelet Therapy in Coronary Artery Disease

Authors: Raghav Sharma, Prathap Kumar, S. P. Prashanth, Yogesh Belagali

Published in: Cardiology and Therapy | Issue 2/2020

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Abstract

Acute coronary syndrome (ACS) is principally driven by platelet aggregation. Dual antiplatelet therapy (DAPT) has demonstrated a reduction in recurrent ischemic events. The newer antiplatelets ticagrelor and prasugrel have demonstrated superiority over clopidogrel. While prasugrel demonstrated benefit in patients scheduled for percutaneous intervention (PCI), benefits of ticagrelor were seen irrespective of the treatment strategy. Current guidelines recommend the use of DAPT for 1 year in all patients with ACS. Ticagrelor 60 mg is recommended for up to 3 years in high-risk patients. DAPT and Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE DAPT) scores are tools to support decision-making in deciding duration of dual antiplatelet therapy.
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Metadata
Title
Dual Antiplatelet Therapy in Coronary Artery Disease
Authors
Raghav Sharma
Prathap Kumar
S. P. Prashanth
Yogesh Belagali
Publication date
01-12-2020
Publisher
Springer Healthcare
Published in
Cardiology and Therapy / Issue 2/2020
Print ISSN: 2193-8261
Electronic ISSN: 2193-6544
DOI
https://doi.org/10.1007/s40119-020-00197-0

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