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European Radiology
Published in: European Radiology 4/2008

01-04-2008 | Urogenital

The utility of diffusion-weighted MR imaging for differentiating uterine sarcomas from benign leiomyomas

Authors: Ken Tamai, Takashi Koyama, Tsuneo Saga, Nobuko Morisawa, Koji Fujimoto, Yoshiki Mikami, Kaori Togashi

Published in: European Radiology | Issue 4/2008

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Abstract

The usefulness of diffusion-weighted (DW) magnetic resonance (MR) imaging for the diagnosis of uterine sarcomas was investigated, as well as whether DW images and quantitative measurement of apparent diffusion coefficient (ADC) values can facilitate differentiating uterine sarcomas from benign leiomyomas. MR images including DW images were obtained in 43 surgically treated patients with 58 myometrial tumors, including seven uterine sarcomas (five leiomyosarcomas and two endometrial stromal sarcomas) and 51 benign leiomyomas (43 ordinary leiomyomas, two cellular leiomyomas and six degenerated leiomyomas). Qualitative analysis of non-enhanced and postcontrast MR images and DW images and quantitative measurement of ADC values were performed for each myometrial tumor. Both uterine sarcomas and cellular leiomyomas exhibited high signal intensity on DW images, whereas ordinary leiomyomas and most degenerated leiomyomas showed low signal intensity. The mean ADC value (10−3 mm2/s) of sarcomas was 1.17 ± 0.15, which was lower than those of the normal myometrium (1.62 ± 0.11) and degenerated leiomyomas (1.70 ± 0.11) without any overlap; however, they were overlapped with those of ordinary leiomyomas and cellular leiomyomas. In addition to morphological features on nonenhanced and postcontrast MR sequences, DW imaging and ADC measurement may have a potential ability to differentiate uterine sarcomas from benign leiomyomas.
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Metadata
Title
The utility of diffusion-weighted MR imaging for differentiating uterine sarcomas from benign leiomyomas
Authors
Ken Tamai
Takashi Koyama
Tsuneo Saga
Nobuko Morisawa
Koji Fujimoto
Yoshiki Mikami
Kaori Togashi
Publication date
01-04-2008
Publisher
Springer-Verlag
Published in
European Radiology / Issue 4/2008
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-007-0787-7

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