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CNS Drugs
Published in: CNS Drugs 11/2005

01-11-2005 | Review Article

The Use of Triptans in the Management of Menstrual Migraine

Authors: Dr Lisa K. Mannix, Julia A. Files

Published in: CNS Drugs | Issue 11/2005

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Abstract

Many women experience headaches, including migraine, in association with their menstrual cycles. Although definitions vary, menstrual migraine generally refers to migraine without aura that occurs within several days prior to and several days after the onset of menses.
Although menstrual migraine has been reported to be more difficult to treat than other types of migraines, there is no evidence from controlled clinical trials to support this assertion. Thus, the pharmacological treatment of menstrual migraine should be similar to that of other types of migraines, except with respect to the use of hormonal manipulations to treat menstrual migraine.
Serotonin 5-HT1B/1D receptor agonists (triptans) are effective for the acute treatment of both menstrual and non-menstrual migraines. When used as acute therapy, a triptan should be administered early, when the headache is still mild in severity. Ideally, an acute therapy will provide rapid and complete pain relief with no disability. Some patients may require preventive therapy for menstrual migraine based on suboptimal response to an adequate trial of acute therapy. Patient diaries that record headache onset, relationship to the menstrual cycle and treatment response through three complete cycles will allow accurate prediction of the onset of menstrual migraine; this information is also needed to make decisions about timing of intermittent preventive therapy. The goals of intermittent preventive therapy are to reduce the frequency, duration and intensity of menstrual migraine attacks.
Clinical studies show that triptans are effective when used as either acute therapy or as intermittent preventive therapy for menstrual migraine. Sumatriptan and zolmitriptan have been evaluated in prospective, randomised, controlled trials for acute treatment. Retrospective analyses and open-label studies also support the use of other triptans as acute therapy. In addition, sumatriptan, frovatriptan, naratriptan and zolmitriptan have been evaluated as intermittent preventive therapy in prospective studies. Thus, data from clinical studies indicate that triptans are effective for the treatment of menstrual migraine.
Literature
1.
Lipton RB, Stewart WF, Diamond S, et al. Prevalence and burden of migraine in the United States: data from the American Migraine Study II. Headache 2001; 41: 646–57PubMedCrossRef
2.
Stewart WF, Simon D, Shechter A, et al. Population variation in migraine prevalence: a meta-analysis. J Clin Epidemiol 1995; 48: 269–80PubMedCrossRef
3.
Stewart WF, Lipton RB, Celentano DD, et al. Prevalence of migraine headache in the United States: relation to age, income, race, and other sociodemographic factors. JAMA 1992; 267: 64–9PubMedCrossRef
4.
Stewart WF, Ricci JA, Chee E, et al. Lost productive time and cost due to common pain conditions in the US workforce. JAMA 2003; 290: 2443–54PubMedCrossRef
5.
Mattsson P. Hormonal factors in migraine: a population-based study of women aged 40 to 74 years. Headache 2003; 43: 27–35PubMedCrossRef
6.
Silberstein SD. The role of sex hormones in headache. Neurology 1992; 42 Suppl. 2: 37–42
7.
8.
Newman LC, McNeal S, O’Quinn S, et al. The prevalence of menstrually associated migraine in a population of IHS migraineurs: results of a follow-up survey to American Migraine Study II (AMSII) [abstract no. S45.002]. Neurology 2002; 58: A331
9.
Johannes CB, Linet MS, Stewart WF, et al. Relationship of headache to phase of the menstrual cycle among young women: a daily diary study. Neurology 1995; 45: 1076–82PubMedCrossRef
10.
Granella F, Sances G, Zanferrari C, et al. Migraine without aura and reproductive life events: a clinical epidemiological study in 1300 women. Headache 1993; 33: 385–9PubMedCrossRef
11.
Stewart WF, Lipton RB, Chee E, et al. Menstrual cycle and headache in a population sample of migraineurs. Neurology 2000; 55: 1517–23PubMedCrossRef
12.
13.
Kornstein SG, Parker AJ. Menstrual migraines: etiology, treatment, and relationship to premenstrual syndrome. Curr Opin Obstet Gynecol 1997; 9: 154–9PubMedCrossRef
14.
15.
16.
17.
18.
Boyle CA. Management of menstrual migraine. Neurology 1999; 53Suppl. 1: S14–8PubMed
19.
Lay CL, Mascellino AM. Menstrual migraine: diagnosis and treatment. Curr Pain Headache Rep 2001; 5: 195–9PubMedCrossRef
20.
Headache Classification Subcommittee of the International Headache Society. The international classification of headache disorders. 2nd ed. Cephalalgia 2004; 24 Suppl. 1: 9–160
21.
Somerville BW. The role of estradiol withdrawal in the etiology of menstrual migraine. Neurology 1972; 22: 355–65PubMedCrossRef
22.
MacGregor EA, Hackshaw A. Prevalence of migraine on each day of the natural menstrual cycle. Neurology 2004; 63: 351–3PubMedCrossRef
23.
Sances G, Granella F, Nappi RE, et al. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia 2003; 23(3): 197–205PubMedCrossRef
24.
Sulak PJ, Scow RD, Precce C, et al. Hormone withdrawal symptoms in oral contraceptive users. Obstet Gynecol 2000; 95: 261–6PubMedCrossRef
25.
Fettes I. Migraine in the menopause. Neurology 1999; 53Suppl. 1: S29–33PubMed
26.
Wang SJ, Fuh JL, Lu SR, et al. Migraine prevalence during menopausal transition. Headache 2003; 43: 470–8PubMedCrossRef
27.
Belfort MA, Saade GR, Snabes M, et al. Hormonal status affects the reactivity of the cerebral vasculature. Am J Obstet Gynecol 1995; 172: 1273–8PubMedCrossRef
28.
D’Andrea G, Hasselmark L, Cananzi AR, et al. Metabolism and menstrual cycle rhythmicity of serotonin in primary headaches. Headache 1995; 35: 216–21PubMedCrossRef
29.
Anselmi B, Tarquini R, Panconesi A, et al. Serum beta-endorphin increase after intravenous histamine treatment of chronic daily headache. Recenti Prog Med 1997; 88(7–8): 321–4PubMed
30.
Mannix LK, Diamond M, Loder E. Women and headache: a treatment approach based on life stages. Cleve Clin J Med 2002; 69(6): 488–500PubMedCrossRef
31.
Calhoun AH. Four hypotheses for understanding menstrual migraine. Female Patient 2004; 29: 38–42
32.
Nattero G, Allais G, De Lorenzo C, et al. Relevance of prostaglandins in true menstrual migraine. Headache 1989; 29: 233–8PubMedCrossRef
33.
Benedetto C, Allais G, Ciochetto D, et al. Pathophysiological aspects of menstrual migraine. Cephalalgia 1997; 17 Suppl. 20: 32–4
34.
35.
Massiou H. Is menstrually associated migraine difficult to treat? Cephalalgia 1999; 19Suppl. 24: 13–8PubMed
36.
Granella F, Sances G, Allais G, et al. Characteristics of menstrual and nonmenstrual attacks in women with menstrually related migraine referred to headache centres. Cephalalgia 2004; 24: 707–16PubMedCrossRef
37.
Pinkerman BF, Holroyd KA. Comparisons of acute treatment for menstrually related and nonmenstrual migraines in a frequent migraine population: a preliminary report [abstract no. OR9]. Headache 2003; 43: 512–3
38.
Silberstein S. The efficacy of zolmitriptan is unaffected by the relationship to menses. Presented at 10th Congress of the International Headache Society; 2001 Jun 29–Jul 2; New York (NY)
39.
Christoph-Diener H, Ferrari M, Mansbach H, SNAP Database Study Group. Predicting the response to sumatriptan: the sumatriptan naratriptan aggregate patient database. Neurology 2004; 63: 520–4PubMedCrossRef
40.
Rapoport AM, Ramadan NM, Adelman JU, et al., on behalf of the 017 Clinical Trial Study Group. Optimizing the dose of zolmitriptan (Zornig, 311C90) for the acute treatment of migraine. Neurology 1997; 49: 1210–8PubMedCrossRef
41.
Schoenen J, Sawyer J. Zolmitriptan (Zornig, 311C90), a novel dual central and peripheral 5HT1B/1D agonist: an overview of efficacy. Cephalalgia 1997; 17 Suppl. 18: 28–40
42.
Loder E. Menstrual migraine: clinical considerations in light of revised diagnostic criteria. Neurol Sci 2005; 26Suppl. 2: s121–4PubMedCrossRef
43.
Cady RK, Sheftell F, Lipton RB, et al. Effect of early intervention with sumatriptan on migraine pain: retrospective analyses of data from three clinical trials. Clin Ther 2000; 22: 1035–48PubMedCrossRef
44.
Cady RK, Lipton RB, Hall C, et al. Treatment of mild headache in disabled migraine sufferers: results of the Spectrum Study. Headache 2000; 40: 792–7PubMedCrossRef
45.
Klapper JA, Rosjo O, Charlesworth B, et al. Treatment of mild migraine with oral zolmitriptan 2.5mg provides high pain-free response rates in patients with significant migraine-related disability [abstract]. Neurology 2002; 58: A416
46.
Silberstein SD. Practice parameter: evidence-based guidelines for migraine headache (an evidence-based review): report of the quality standards subcommittee of the American Academy of Neurology. Neurology 2000; 55(6): 754–62PubMedCrossRef
47.
Gross M, Barrie M, Bates D, et al. The efficacy of sumatriptan in menstrual migraine. Eur J Neurol 1995; 2 Suppl. 1: 144–5
48.
Gross ML, Barrie M, Bates D, et al. The efficacy of oral sumatriptan in menstrual migraine: a prospective study [abstract]. Cephalalgia 1995; 15 Suppl. 14: 227
49.
Facchinetti F, Bonellie G, Kanasniemi P, et al. The efficacy and safety of subcutaneous sumatriptan in the acute treatment of menstrual migraine. The Sumatriptan Menstrual Migraine Study Group. Obstet Gynecol 1995; 86: 911–6
50.
Nett R, Landy S, Shackelford S, et al. Pain-free efficacy after treatment with sumatriptan in the mild pain phase of menstrually associated migraine. Obstet Gynecol 2003; 102: 835–42PubMedCrossRef
51.
Imitrex [data on file]. Research Triangle Park (NC): GlaxoSmithKline, 2004
52.
Tuchman M, Abu-Shakra S, Silberstein SD, et al. Oral zolmitriptan exhibits high efficacy and low recurrence rates in the acute treatment of true menstrual migraine: results of a randomized controlled trial [abstract no. OR8]. Headache 2003; 43: 512
53.
Tuchman M, Abu-Shakra S, Silberstein SD, et al. Oral zolmitriptan is efficacious as acute therapy for pure menstrual migraine: results of a second large prospective, multicenter, placebo-controlled trial [abstract no. S15.003]. Neurology 2003; 60Suppl. 1: A94
54.
Loder E, Silberstein SD, Abu-Shakra S, et al. Efficacy and tolerability of oral zolmitriptan in menstrually associated migraine: a randomized, prospective, parallel-group, double-blind, placebo-controlled study. Headache 2004; 44: 120–30PubMedCrossRef
55.
Silberstein SD, Elkind AH, Schrieber C, et al. A randomized trial of frovatriptan for the intermittent prevention of menstrual migraine. Neurology 2004; 63: 261–9PubMedCrossRef
56.
Tepper S, Freitag F. Intermittent use of frovatriptan for prevention of menstrually associated migraine is effective and does not cause rebound migraine in the postdosing period [abstract no. S162]. Headache 2003; 43: 585
57.
Smith TR, Nett R. Frovatriptan is well tolerated during repeated use for intermittent prevention of menstrually associated migraine [abstract no. S165]. Headache 2003; 43: 586
58.
Singer R, Schim J. Frovatriptan for prophylaxis of menstrually associated migraine: efficacy and tolerability in patients using oral contraceptives compared to nonusers [abstract S169]. Headache 2003; 43: 587
59.
Newman L, Mannix LK, Landy S, et al. Naratriptan as short-term prophylaxis of menstrually associated migraine: a randomized, double-blind, placebo-controlled study. Headache 2001; 41: 248–56PubMedCrossRef
60.
Amerge [data on file]. Research Triangle Park (NC): GlaxoSmithKline, 2004
61.
Nett R, Mannix LK, Landy S, et al. A randomized, double-blind, placebo-controlled, parallel-group evaluation of oral naratriptan 1mg twice daily as prophylactic treatment for menstrually associated migraine [abstract no. S15.006]. Neurology 2003; 60Suppl. 1: A95
62.
Diamond M, Aurora S, Ames M, et al. Naratriptan for intermittent prophylaxis for menstrually associated migraine: an analysis of migraine-free days [abstract no. F72]. Headache 2003; 40: 548–9
63.
Brandes J, Savani N, Alderton C, et al. Naratriptan vs placebo for intermittent prophylaxis for menstrually associated migraine (MAM): analysis of migraine-free days [abstract no. P5N55]. Cephalalgia 2003; 23: 705
64.
Mannix L, Brandes J, Shackelford S, et al. Naratriptan for intermittent prophylaxis for menstrually associated migraine: a review of efficacy and tolerability [abstract no. S167]. Headache 2003; 40: 587
65.
Brandes J, Savani N, Kwong JW, et al. Patient satisfaction with oral naratriptan for intermittent prophylaxis of menstrually associated migraine: results from a double-blind, placebo-controlled, parallel group study [abstract no. P5-N54]. Cephalalgia 2003; 23: 705
66.
Brandes J, Smith T, Powers C, et al. Long-term safety, tolerability and efficacy of naratriptan 1mg BID in the prophylactic treatment of menstrually associated migraine [abstract no. S102]. Headache 2002; 42: 451
67.
Karageorgiou CE, Hatzidaki G, Robotis G, et al. The role of naratriptan as a prophylaxis to the menstrual migraine: a pilot comparative to naproxen study [abstract no. P2-127]. Cephalalgia 2001; 21: P2
68.
Riemasch-Becker C, Faust W, Schwittman B. Acute treatment of menstrual migraine attacks with s.c. sumatriptan (poster). First Congress of the European Federation of Neurological Sciences; 1993 Dec, Berlin, Germany
69.
MacGregor EA, Keywood C. Frovatriptan is effective in menstrually associated migraine. Poster presented at Headache World 2000, 7; London, UK
70.
Solbach MP, Waymer RS. Treatment of menstruation-associated migraine headache with subcutaneous sumatriptan. Obstet Gynecol 1993; 82: 769–72PubMed
71.
Savani N, Loftus J, Boswell D. A randomized, double-blind, placebo-controlled, parallel group evaluation of sumatriptan 50mg and 100mg tablets administered during the mild pain phase of a menstrually associated migraine attack [abstract no. PB.30]. Cephalalgia 2002; 22: 606
72.
Winner P, Lowy MT, Fletcher PE, et al. Confirmation of the long-term safety and efficiency of oral 311C in the acute treatment of migraine: demographic analysis from a study of >30000 treated attacks [abstract no. P405]. Eur J Neurol 1996; 3 Suppl. 5: 151
73.
Newman LC, Lipton RB, Lay CL, et al. A pilot study of oral sumatriptan as intermittent prophylaxis of menstruation-related migraine. Neurology 1998; 51: 307–9PubMedCrossRef
74.
Dalessio DJ, Brown DL, Solbach P, et al. Oral 311C90 is effective in treatment of menstrual migraine [abstract]. Cephalalgia 1996; 16: 400–1
75.
Solomon GD, Cady RK, Klapper JA, et al. Clinical efficacy and tolerability of 2.5mg zolmitriptan for the acute treatment of migraine. Neurology 1997; 49: 1219–25PubMedCrossRef
76.
Silberstein S. Zolmitriptan is effective in the treatment of men-strually associated migraine attacks [abstract no. P2-K34]. Cephalalgia 2001; 21: 420
77.
Silberstein S, Norman B, Jiang K, et al. Rizatriptan is effective in menstrual migraine [abstract no. P03.047]. Neurology 1999; 52Suppl. 2: A203
78.
Silberstein SD, Massiou H, Le Jeunne C, et al. Rizatriptan in the treatment of menstrual migraine. Obstet Gynecol 2000; 96: 237–42PubMedCrossRef
79.
Massiou H, Silberstein KA, McCarroll KA, et al. Efficacy of rizatriptan in menstrual migraine: freedom from pain and associated symptoms at 2-h and 24-h sustained pain-free status. Cephalalgia 2000; 20: 343–4
80.
Silberstein SD, Massiou H, McCarroll KA, et al. Further evaluation of rizatriptan in menstrual migraine: retrospective analysis of long-term data. Headache 2002; 42: 917–23PubMedCrossRef
81.
Silberstein SD, Massiou H, McCarroll KA, et al. Long-term efficacy of rizatriptan wafers in menstrual migraine [abstract no. P2-K34]. Cephalalgia 2001; 21: 420
82.
Pitei D, Hettiarachchi J. Efficacy of eletriptan in treating women with menstrually associated migraine and women on oral contraceptives or hormone replacement therapy [abstract]. Obstet Gynecol 2000; 95 Suppl. 1: 32SCrossRef
83.
Hettiarachchi J, Pitei D. Oral eletriptan is effective in treating menstrually associated migraine and migraine in women on oral contraceptives or hormone replacement [abstract]. Headache 2000; 40: 411
84.
Lay C, Rubens R, Hylan T, et al. Acute treatment of migraine in women: efficacy, tolerability and pharmacokinetics of eletriptan. Poster presented at 18th Annual National Conference of the American Academy of Nurse Practitioners; 2003 Jun 28–Jul 2; Anaheim (CA)
85.
MacGregor EA, Alderman J, Sikes C, et al. Efficacy, tolerability, and pharmacokinetics of eletriptan in women [abstract no. P4M14]. Cephalalgia 2003; 23: 688
86.
Dawson A, Landy S, Kwong J, et al. Randomized, double-blind, placebo-controlled parallel-group evaluation of patient satisfaction with oral sumatriptan administered in mild phase during acute treatment of menstrually associated migraine [abstract no. P5-N29]. Cephalalgia 2003; 23: 698
87.
Goldstein J, Matthew N, Rapoport AM. The safety and tolerability of frovatriptan, a selective 5HT1B/1D agonist, used for prophylaxis of menstrually associated migraine [abstract no. P06.141]. Neurology 2003; 60Suppl. 1: A94
88.
Tuchman M, Hee A, Emeribe U. Oral zolmitriptan 2.5mg demonstrates high efficacy oand good tolerability in the prophylactic treatment of menstrual migraine headaches [abstract]. Headache 2005; 45: 771
89.
International 311C90 Long-term Study Group. The long-term tolerability and efficacy of oral zolmitriptan (Zomig, 311C90) in the acute treatment of migraine: an international study. Headache 1998; 38: 173–83CrossRef
90.
Freitag FG. Acute treatment of migraine and the role of triptans. Curr Neurol Neurosci Rep 2001; 1: 125–32PubMedCrossRef
91.
Imitrex [package insert]. Research Triangle Park (NC): GlaxoSmithKline, 2003
92.
Maxalt [package insert]. Whitehouse Station (NJ): Merck & Co Inc, 2003
93.
Zomig [package insert]. Wilmington (DE): AstraZeneca LP, 2003
94.
Axert [package insert]. Raritan (NJ): Ortho-McNeil Pharmaceutical Inc, 2003
95.
Relpax [package insert]. New York (NY): Pfizer Inc, 2002
96.
Amerge [package insert]. Research Triangle Park (NC): GlaxoSmithKline, 2003
97.
Frova [package insert]. San Diego (CA): Elan Pharmaceuticals, 2001
98.
Ferrari MD, Roon KI, Lipton RB, et al. Oral triptans (serotonin 5-HT (1B/1D) agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet 2001; 359: 1668–75CrossRef
99.
Geraud G, Keywood C, Senard JM. Migraine headache recurrence: relationship to clinical, pharmacological, and pharmacokinetic properties of triptans. Headache 2003; 43: 376–88PubMedCrossRef
100.
Gladstone JP, Dodick DW. Acute migraine: which triptan? Practical Neurol 2004; 4: 6–19CrossRef
101.
Hall GC, Brown MM, MacRae JM, et al. Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice. Neurology 2004; 62: 563–8PubMedCrossRef
102.
Winner P, Mannix LK, Putnam DG, et al. Pain-free results with sumatriptan taken at the first sign of migraine pain: 2 randomized, double-blind, placebo-controlled studies. Mayo Clin Proc 2003; 78: 1214–22PubMedCrossRef
103.
Ilmaavirta M, Lodrua JV, Boswell D. A randomised, double-blind, placebo-controlled, parallel-group evaluation of sumatriptan 50mg and 100mg tablets administered during the mild pain phase of a menstrually associated migraine attack [abstract no. P2-158]. Eur J Neurol 2002; 9: 149
104.
Zomig [data on file]. Wilmington (DE): AstraZeneca LP, 2004
105.
Massiou H. Efficacy and tolerability of zolmitriptan in the acute treatment of menstrually and nonmenstrually associated migraine [abstract no. II-G1-44]. Cephalalgia 1999; 19: 368
106.
Visser WH, Klein KB, Cox RC, et al. 311C90, a new central and peripherally acting 5-HT1D receptor agonist in the acute oral treatment of migraine: a double-blind, placebo-controlled, dose-range finding study. Neurology 1996; 46: 522–6PubMedCrossRef
107.
Gallagher RM, Dennish G, Spierings EL, et al. A comparative trial of zolmitriptan and sumatriptan for the acute oral treatment of migraine. Headache 2000; 40: 119–28PubMedCrossRef
108.
Gruffyd-Jones K, Kies B, Middleton A, et al. Zolmitriptan versus sumatriptan for the acute oral treatment of migraine: a randomized, double-blind, international study. Eur J Neurol 2001; 8: 237–45PubMedCrossRef
109.
Loder E, Silberstein S, Giammarco R, et al. Oral zolmitriptan exhibits efficacy as early as 30 minutes in menstrually associated migraine: results of a large multicenter placebo-controlled study. Neurology 2002; 58Suppl. 3: A414–5
110.
Tepper SJ, Donnan GA, Dowson AJ, et al. A long-term study to maximise migraine relief with zolmitriptan. Curr Med Res Opin 1999; 15: 254–71PubMedCrossRef
111.
Salonen R, Saiers J. Sumatriptan is effective in the treatment of menstrual migraine: a review of prospective studies and retrospective analyses. Cephalalgia 1999; 19(1): 16–9PubMedCrossRef
112.
Landy S, Savani N, Shackelford S, et al. Efficacy and tolerability of sumatriptan tablets administered during the mid-pain phase onf menstrually associated migraine. Int J Clin Pract 2004; 58(10): 913–9PubMedCrossRef
113.
Loder E, Silberstein SD, Abdu-Shakra S, et al. Efficacy and tolerability of oral zolmitriptan in menstrually associated migraine: a randomized, prospective, parallel-group, double-blind, placebo-controlled study. Headache 2004; 44(2): 120–30PubMedCrossRef
114.
Savani N, Loftus J, Mansbach H, et al. A randomized, double-blind, placebo-controlled, parallel-group evaluation of oral naratriptan 1mg twice daily as prophylactic treatment for menstrually associated migraine [abstract no. P-45]. Cephalalgia 2002; 22: 25
115.
Spierings ELH, Cough JR, Blumenthal HJ. Clinical characteristics of menstrually associated migraine: a review of results from a study of the use of frovatriptan for prophylaxis of menstrually associated migraine [abstract no. P06.140]. Neurology 2003; 60Suppl. 1: A493–4
116.
Blumenthal H, Spierings L, Couch J. The clinical characteristics of menstrually associated migraine as demonstrated in a study of frovatriptan as intermittent prevention [abstract no. F69]. Headache 2003; 40: 547
117.
Kwong JW, Putnam GD, Loftus JV, et al. Patient satisfaction with oral naratriptan for intermittent prophylaxis of menstrually associated migraine: results from a double-blind, placebo-controlled, parallel-group study [abstract no. S166]. Headache 2003; 43: 586–7
118.
MacGregor EA, Tobin J, Hutchison J. An interim analysis of the safety and tolerability of frovatriptan for the prevention of menstrually related migraine headaches [abstract]. Headache 2005; 45: 822
119.
Moschiano R, Allais G, Grazzi L, et al. Naratriptan in the short-term prophylaxis of pure menstrual migraine. Neurol Sci 2005; Suppl. 26: S162-6
120.
Calhoun AH. Four hypotheses for understanding menstrual migraine. Female Patient 2004; 29: 38–45
121.
Rossouw JE, Anderson GL, Prentice RL; Writing Group for the Women’s Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002; 288: 321–33PubMedCrossRef
122.
Hersh AL, Stefanick ML, Stafford RS. National use of postmenopausal hormone therapy. JAMA 2004; 291: 47–53PubMedCrossRef
123.
124.
Sulak PJ, Cressman BE, Waldrop E, et al. Extending the duration of active oral contraceptive pills to manage hormone withdrawal symptoms. Obstet Gynecol 1997; 89: 179–83PubMedCrossRef
125.
Anderson FD, Hait H. A multicenter, randomized study of an extended-cycle oral contraceptive. Contraception 2003; 68: 89–96PubMedCrossRef
126.
Mortola JF, Girton L, Fischer U. Successful treatment of severe premenstrual syndrome by combined use of gonadotropin-releasing hormone agonist and estrogen/progestin. J Clin Endocrinol Metab 1991; 72: 252A-FCrossRef
127.
Burke BE, Olson RD, Cusack BJ. Randomized, controlled trial of phytoestrogen in the prophylactic treatment of menstrual migraine. Biomed Pharmacother 2002; 56: 283–8PubMedCrossRef
128.
Ferrante F, Fusco E, Calabresi P, et al. Phyto-oestrogens in the prophylaxis of menstrual migraine. Clin Neuropharmacol 2004; 27(3): 137–40PubMedCrossRef
129.
130.
Waters WE, Connor PJ. Epidemiology of headache and migraine in women. J Neurol Neurosurg Psychiatry 1971; 34: 148–53PubMedCrossRef
Metadata
Title
The Use of Triptans in the Management of Menstrual Migraine
Authors
Dr Lisa K. Mannix
Julia A. Files
Publication date
01-11-2005
Publisher
Springer International Publishing
Published in
CNS Drugs / Issue 11/2005
Print ISSN: 1172-7047
Electronic ISSN: 1179-1934
DOI
https://doi.org/10.2165/00023210-200519110-00005

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