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CNS Drugs

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01-11-2005 | Adis Drug Profile

Rotigotine

A Viewpoint by Tomislav Babic

Author: Tomislav Babic

Published in: CNS Drugs | Issue 11/2005

Excerpt

Dopamine agonists are gaining acceptance not only for the treatment of advanced Parkinson’s disease but also for the initial treatment of early-stage disease. This represents a change from earlier concepts on the management of Parkinson’s disease, which were mainly based on the use of levodopa coupled with dopa-decarboxylase inhibitors. However, the daily ‘peak’ and ‘trough’ blood concentrations of the multiple-dose oral dopamine agonists result in pulsatile stimulation of dopamine receptors, which may contribute to the pathogenesis of motor complications. …

Title: Rotigotine
A Viewpoint by Tomislav Babic
Author: Tomislav Babic
Publication date: 01-11-2005
Publisher: Springer International Publishing
Published in: CNS Drugs / Issue 11/2005
Print ISSN: 1172-7047
Electronic ISSN: 1179-1934
DOI: https://doi.org/10.2165/00023210-200519110-00007

At a glance: The STEP trials

Springer Medicine

Rotigotine

A Viewpoint by Tomislav Babic

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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Rotigotine

Rotigotine