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Open Access 01-12-2008 | Case report

The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site

Authors: Gian Paolo Spinelli, Evelina Miele, Federica Tomao, Luigi Rossi, Giulia Pasciuti, Angelo Zullo, Federica Zoratto, Jose Nunnari, Giovanni Codacci Pisanelli, Silverio Tomao

Published in: World Journal of Surgical Oncology | Issue 1/2008

Abstract

Background

Esophageal squamous cell carcinoma is a relative common malignancy with a very poor prognosis, even adopting an integrated and multidisciplinary approach. According to the literature, gastrointestinal stromal tumors (GISTs) rarely originate from the esophagus. Moreover there are not reports of synchronous occurrence of squamous cell carcinoma and GIST at esophageal site.

Case presentation

We describe a case of a 74 year old patient who underwent surgery for squamous cell carcinoma of the lower third of the esophagus with an incidental pathologic diagnosis of a concomitant GIST in the thoracic tract.

Conclusion

In literature there is no evidence of concomitant squamous carcinoma and GIST of the thoracic esophagus, even if esophageal GISTs are sometimes described. The occasional finding of this neoplastic lesion underlines the importance of a carefully pathological diagnosis for its identification. Surgery, followed by a multidisciplinary approach remains the first-line treatment in both squamous and stromal neoplasm.

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Title: The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site
Authors: Gian Paolo Spinelli
Evelina Miele
Federica Tomao
Luigi Rossi
Giulia Pasciuti
Angelo Zullo
Federica Zoratto
Jose Nunnari
Giovanni Codacci Pisanelli
Silverio Tomao
Publication date: 01-12-2008
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2008
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-6-116

Keynote webinar | Spotlight on medication adherence

Springer Medicine

The synchronous occurrence of squamous cell carcinoma and gastrointestinal stromal tumor (GIST) at esophageal site

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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