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Published in: Current Fungal Infection Reports 4/2018

01-12-2018 | Clinical Mycology Lab Issues (S Córdoba, Section Editor)

The Southern Endemic Zone of Paracoccidioidomycosis: Epidemiological Approach in Northeast Argentina

Authors: Gustavo Giusiano, Florencia Rojas, Javier Mussin, Liliana Alegre, María de los Ángeles Sosa

Published in: Current Fungal Infection Reports | Issue 4/2018

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Abstract

Purpose of Review

Paracoccidioidomycosis (PCM) is one of the most prevalent systemic endemic mycosis in Latin America caused by species of an environmental fungus of the genus Paracoccidioides. In Argentina, the endemic area with the highest incidence is located in the Northeast. This review presents the current aspects of PCM epidemiology influenced by global and particular climatic anomalies.

Recent Findings

An increase of cases with particularly features, in the diagnosis and clinical manifestations, delaying the diagnosis was observed. Two genotypes of Paracoccidioides are circulating and, probably, are related to a considerable percentage of non-reactive serological tests obtained in proven cases of PCM.

Summary

The traditional view of the PCM epidemiology in the southern endemic zone area must be reconsidered. A higher level of premonition is now required in Northeast Argentina and, may be, in bordering countries. The particular characteristics both in the clinic and in the diagnosis currently observed suggest a new trend in PCM.
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Metadata
Title
The Southern Endemic Zone of Paracoccidioidomycosis: Epidemiological Approach in Northeast Argentina
Authors
Gustavo Giusiano
Florencia Rojas
Javier Mussin
Liliana Alegre
María de los Ángeles Sosa
Publication date
01-12-2018
Publisher
Springer US
Published in
Current Fungal Infection Reports / Issue 4/2018
Print ISSN: 1936-3761
Electronic ISSN: 1936-377X
DOI
https://doi.org/10.1007/s12281-018-0324-y

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