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Archives of Virology
Published in: Archives of Virology 7/2013

01-07-2013 | Brief Report

The simultaneous occurrence of human norovirus and hepatitis E virus in a Norway rat (Rattus norvegicus)

Authors: Sandro Wolf, Jochen Reetz, Reimar Johne, Ann-Charlotte Heiberg, Samuel Petri, Hanna Kanig, Rainer G. Ulrich

Published in: Archives of Virology | Issue 7/2013

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Abstract

Wild rats can be reservoirs and vectors for several human pathogens. An initial RT-PCR screening of the intestinal contents of Norway rats trapped in the sewer system of Copenhagen, Denmark, for caliciviruses revealed the presence of a human norovirus in one of 11 rodents. Subsequent phylogenetic analysis of the ~4.0-kb 3′-terminus of the norovirus genome resulted in the identification of a recombinant GI.b/GI.6 strain. The simultaneous detection of hepatitis E virus-like particles in the feces of this rat by transmission electron microscopy was confirmed by RT-PCR and sequence determination, resulting in the identification of a novel rat hepatitis E virus.
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Metadata
Title
The simultaneous occurrence of human norovirus and hepatitis E virus in a Norway rat (Rattus norvegicus)
Authors
Sandro Wolf
Jochen Reetz
Reimar Johne
Ann-Charlotte Heiberg
Samuel Petri
Hanna Kanig
Rainer G. Ulrich
Publication date
01-07-2013
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 7/2013
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-013-1646-2

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