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Published in: Surgical Endoscopy 2/2017

01-02-2017

The safety of laparoscopic sleeve gastrectomy among diabetic patients

Authors: Collin Creange, Monica Sethi, George Fielding, Christine Ren-Fielding

Published in: Surgical Endoscopy | Issue 2/2017

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Abstract

Aims

Laparoscopic sleeve gastrectomy (LSG) is a commonly performed bariatric procedure. Although bariatric surgery is becoming increasingly recognized as a treatment option for diabetes, there remain concerns about the operative risks faced by diabetic patients. This study’s objective was to determine the safety of bariatric surgery in diabetic patients, specifically the type 2 diabetic (T2DM) population.

Methods

Patients over 18 years of age with a body mass index (BMI) ≥ 35 kg/m2 who underwent LSG in 2012 in the ACS-NSQIP database were identified. Emergency cases were excluded from analysis. Data included patient demographics, comorbidities, length of stay, and 30-day complications. The primary outcome was 30-day overall complication rate, and secondary outcomes included major complications and reoperation rates.

Results

There were 6399 LSG in the NSQIP database in 2012. Three hundred and twenty-two patients were excluded for BMI < 35, and 15 cases were deemed emergencies and excluded. Of the 6062 LSG who met the study criteria, 4726 (78 %) of patients were non-diabetic, 941 (15.5 %) had T2DM, and 395 (6.5 %) had T1DM. T2DM patients were more likely to be male (28.9 vs. 19.3 %, p < 0.001), were older (47.6 years vs. 42.5 years, p < 0.001), and had a higher BMI (46.4 vs. 45.7 kg/m2, p = 0.027) compared with non-diabetics. The overall 30-day complication rate did not differ between groups (6.5 % T2DM vs. 5.6 % non-diabetic, p = 0.292). After controlling for possible confounders, T2DM remained at no increased risk of 30-day complications (OR 1.16, 95 % CI 0.87–1.55, p = 0.301). In sub-analyses of specific complications, T2DM had a slightly higher rate of blood transfusions (1.8 vs. 1.0 %, p = 0.037). Other postoperative complications did not differ between groups. The 30-day complication rate for type 1 diabetics was greater than for T2DM (9.9 vs. 6.5 %, p = 0.031) and non-diabetics (9.9 vs. 5.6 %, p < 0.001).

Conclusion

Laparoscopic sleeve gastrectomy is a safe procedure for type 2 diabetics with regard to early postoperative complications.
Literature
1.
go back to reference Sanders LJ (2002) From Thebes to Toronto and the 21st century: an incredible journey. Diabetes Spectr 15:56–60CrossRef Sanders LJ (2002) From Thebes to Toronto and the 21st century: an incredible journey. Diabetes Spectr 15:56–60CrossRef
3.
go back to reference Tao W et al (2015) Causes and risk factors for mortality within 1 year after obesity surgery in a population-based cohort study. Surg Obes Relat Dis 11(2):399–405CrossRefPubMed Tao W et al (2015) Causes and risk factors for mortality within 1 year after obesity surgery in a population-based cohort study. Surg Obes Relat Dis 11(2):399–405CrossRefPubMed
4.
go back to reference Lin X et al (2015) Diabetes and risk of anastomotic leakage after gastrointestinal surgery. J Surg Res 196(2):294–301CrossRefPubMed Lin X et al (2015) Diabetes and risk of anastomotic leakage after gastrointestinal surgery. J Surg Res 196(2):294–301CrossRefPubMed
5.
go back to reference Rawlins L et al (2013) Effect of elevated hemoglobin A1c in diabetic patients on complication rates after Roux-en-Y gastric bypass. Surg Obes Relat Dis 9(5):749–752CrossRefPubMed Rawlins L et al (2013) Effect of elevated hemoglobin A1c in diabetic patients on complication rates after Roux-en-Y gastric bypass. Surg Obes Relat Dis 9(5):749–752CrossRefPubMed
7.
go back to reference Schauer PR et al (2014) Bariatric surgery versus intensive medical therapy for diabetes—3-year outcomes. N Engl J Med 370(21):2002–2013CrossRefPubMed Schauer PR et al (2014) Bariatric surgery versus intensive medical therapy for diabetes—3-year outcomes. N Engl J Med 370(21):2002–2013CrossRefPubMed
9.
go back to reference Mingrone G et al (2012) Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 366(17):1577–1585CrossRefPubMed Mingrone G et al (2012) Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med 366(17):1577–1585CrossRefPubMed
10.
go back to reference Sultan S et al (2010) Five-year outcomes of patients with type 2 diabetes who underwent laparoscopic adjustable gastric banding. Surg Obes Relat Dis 6(4):373–376CrossRefPubMed Sultan S et al (2010) Five-year outcomes of patients with type 2 diabetes who underwent laparoscopic adjustable gastric banding. Surg Obes Relat Dis 6(4):373–376CrossRefPubMed
11.
go back to reference Edelman S et al (2014) Control of type 2 diabetes after 1 year of laparoscopic adjustable gastric banding in the helping evaluate reduction in obesity (HERO) study. Diabetes Obes Metab 16(10):1009–1015CrossRefPubMed Edelman S et al (2014) Control of type 2 diabetes after 1 year of laparoscopic adjustable gastric banding in the helping evaluate reduction in obesity (HERO) study. Diabetes Obes Metab 16(10):1009–1015CrossRefPubMed
12.
go back to reference Mallipedhi A et al (2014) Temporal changes in glucose homeostasis and incretin hormone response at 1 and 6 months after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 10(5):860–869CrossRefPubMed Mallipedhi A et al (2014) Temporal changes in glucose homeostasis and incretin hormone response at 1 and 6 months after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis 10(5):860–869CrossRefPubMed
13.
go back to reference Lee WJ et al (2014) Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial and study of incretin effect. Obes Surg 24(9):1552–1562CrossRefPubMed Lee WJ et al (2014) Laparoscopic sleeve gastrectomy versus single anastomosis (mini-) gastric bypass for the treatment of type 2 diabetes mellitus: 5-year results of a randomized trial and study of incretin effect. Obes Surg 24(9):1552–1562CrossRefPubMed
14.
go back to reference Khan MA et al (2013) Perioperative risk factors for 30-day mortality after bariatric surgery: is functional status important? Surg Endosc 27(5):1772–1777CrossRefPubMed Khan MA et al (2013) Perioperative risk factors for 30-day mortality after bariatric surgery: is functional status important? Surg Endosc 27(5):1772–1777CrossRefPubMed
15.
go back to reference Livingston EH et al (2007) Development of bariatric surgery-specific risk assessment tool. Surg Obes Relat Dis 3(1):14–20 (discussion 20) CrossRefPubMed Livingston EH et al (2007) Development of bariatric surgery-specific risk assessment tool. Surg Obes Relat Dis 3(1):14–20 (discussion 20) CrossRefPubMed
16.
go back to reference Nguyen NT et al (2013) Proposal for a bariatric mortality risk classification system for patients undergoing bariatric surgery. Surg Obes Relat Dis 9(2):239–246CrossRefPubMed Nguyen NT et al (2013) Proposal for a bariatric mortality risk classification system for patients undergoing bariatric surgery. Surg Obes Relat Dis 9(2):239–246CrossRefPubMed
17.
go back to reference Aminian A et al (2015) Development of a sleeve gastrectomy risk calculator. Surg Obes Relat Dis 11(4):758–764CrossRefPubMed Aminian A et al (2015) Development of a sleeve gastrectomy risk calculator. Surg Obes Relat Dis 11(4):758–764CrossRefPubMed
18.
19.
go back to reference Schwartz ML, Drew RL, Chazin-Caldie M (2003) Laparoscopic Roux-en-Y gastric bypass: preoperative determinants of prolonged operative times, conversion to open gastric bypasses, and postoperative complications. Obes Surg 13(5):734–738CrossRefPubMed Schwartz ML, Drew RL, Chazin-Caldie M (2003) Laparoscopic Roux-en-Y gastric bypass: preoperative determinants of prolonged operative times, conversion to open gastric bypasses, and postoperative complications. Obes Surg 13(5):734–738CrossRefPubMed
20.
go back to reference Wit MA et al (2013) Diabetes mellitus and its impact on long-term outcomes after coronary artery bypass graft surgery. Acta Diabetol 50(2):123–128CrossRefPubMed Wit MA et al (2013) Diabetes mellitus and its impact on long-term outcomes after coronary artery bypass graft surgery. Acta Diabetol 50(2):123–128CrossRefPubMed
21.
22.
go back to reference Conrotto F et al (2014) Impact of diabetes mellitus on early and midterm outcomes after transcatheter aortic valve implantation (from a multicenter registry). Am J Cardiol 113(3):529–534CrossRefPubMed Conrotto F et al (2014) Impact of diabetes mellitus on early and midterm outcomes after transcatheter aortic valve implantation (from a multicenter registry). Am J Cardiol 113(3):529–534CrossRefPubMed
24.
go back to reference Price SA et al (2014) Obesity is associated with retinopathy and macrovascular disease in type 1 diabetes. Obes Res Clin Pract 8(2):e178–e182CrossRefPubMed Price SA et al (2014) Obesity is associated with retinopathy and macrovascular disease in type 1 diabetes. Obes Res Clin Pract 8(2):e178–e182CrossRefPubMed
26.
go back to reference Schauer PR et al (2003) Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg 238(4):467–484 (discussion 84-5) PubMedPubMedCentral Schauer PR et al (2003) Effect of laparoscopic Roux-en Y gastric bypass on type 2 diabetes mellitus. Ann Surg 238(4):467–484 (discussion 84-5) PubMedPubMedCentral
27.
go back to reference Adams TD et al (2007) Long-term mortality after gastric bypass surgery. N Engl J Med 357(8):753–761CrossRefPubMed Adams TD et al (2007) Long-term mortality after gastric bypass surgery. N Engl J Med 357(8):753–761CrossRefPubMed
29.
go back to reference Ikramuddin S et al (2013) Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA 309(21):2240–2249CrossRefPubMedPubMedCentral Ikramuddin S et al (2013) Roux-en-Y gastric bypass vs intensive medical management for the control of type 2 diabetes, hypertension, and hyperlipidemia: the Diabetes Surgery Study randomized clinical trial. JAMA 309(21):2240–2249CrossRefPubMedPubMedCentral
Metadata
Title
The safety of laparoscopic sleeve gastrectomy among diabetic patients
Authors
Collin Creange
Monica Sethi
George Fielding
Christine Ren-Fielding
Publication date
01-02-2017
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 2/2017
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-016-5053-0

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