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Journal of Assisted Reproduction and Genetics
Published in: Journal of Assisted Reproduction and Genetics 3/2024

19-02-2024 | Embryo Biology

The role of CoQ10 in embryonic development

Authors: Xueke He, Hao Chen, Minjun Liao, Xiaomei Zhao, Dawei Zhang, Miao Jiang, Zhisheng Jiang

Published in: Journal of Assisted Reproduction and Genetics | Issue 3/2024

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Abstract

Coenzyme Q10 (CoQ10) is a natural component widely present in the inner membrane of mitochondria. CoQ10 functions as a key cofactor for adenosine triphosphate (ATP) production and exhibits antioxidant properties in vivo. Mitochondria, as the energy supply center of cells, play a crucial role in germ cell maturation and embryonic development, a complicated process of cell division and cellular differentiation that transforms from a single cell (zygote) to a multicellular organism (fetus). Here, we discuss the effects of CoQ10 on oocyte maturation and the important role of CoQ10 in the growth of various organs during different stages of fetal development. These allowed us to gain a deeper understanding of the pathophysiology of embryonic development and the potential role of CoQ10 in improving fertility quality. They also provide a reference for further developing its application in clinical treatments.
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Metadata
Title
The role of CoQ10 in embryonic development
Authors
Xueke He
Hao Chen
Minjun Liao
Xiaomei Zhao
Dawei Zhang
Miao Jiang
Zhisheng Jiang
Publication date
19-02-2024
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 3/2024
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-024-03052-6

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