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Current Diabetes Reports
Published in: Current Diabetes Reports 2/2014

01-02-2014 | Diabetes and Pregnancy (CJ Homko, Section Editor)

The Relationship and Potential Mechanistic Pathways Between Sleep Disturbances and Maternal Hyperglycemia

Authors: Bilgay Izci-Balserak, Grace W. Pien

Published in: Current Diabetes Reports | Issue 2/2014

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Abstract

This paper reviews recent work investigating the influence of sleep disturbances on maternal hyperglycemia, particularly gestational diabetes mellitus (GDM). The incidence and prevalence of hyperglycemia are increasing worldwide, which is cause for concern because GDM and even mild hyperglycemia are associated with adverse pregnancy outcomes. A better understanding of sleep-related risk factors for maternal hyperglycemia is an important health matter. Evidence demonstrates associations between sleep disturbances, especially sleep-disordered breathing, and hyperglycemia, but causal effects and the underlying mechanisms linking these conditions have not been fully elucidated. Subjective sleep assessments show associations between sleep disturbances and maternal hyperglycemia. There are, however, few studies using objective measures to support these findings. Large prospective studies are required to examine causal relationships between sleep disturbances and maternal hyperglycemia. There is also a need for smaller mechanistic studies to understand the pathophysiology. Furthermore, interventional studies are required to address whether improvement of sleep parameters can prevent/decrease the risk of developing maternal hyperglycemia. Taken together, the data suggests that sleep disturbances during pregnancy are important to identify and manage in order to minimize maternal hyperglycemia and GDM, and improve maternal and fetal well-being.
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Metadata
Title
The Relationship and Potential Mechanistic Pathways Between Sleep Disturbances and Maternal Hyperglycemia
Authors
Bilgay Izci-Balserak
Grace W. Pien
Publication date
01-02-2014
Publisher
Springer US
Published in
Current Diabetes Reports / Issue 2/2014
Print ISSN: 1534-4827
Electronic ISSN: 1539-0829
DOI
https://doi.org/10.1007/s11892-013-0459-8

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