Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Systematic Reviews
Published in: Systematic Reviews 1/2016

Open Access 01-12-2016 | Protocol

The range of peripapillary retinal nerve fibre layer and optic disc parameters, in children aged up to but not including 18 years of age who were born prematurely: protocol for a systematic review

Authors: Alexandra L. Creavin, Cathy E. M. Williams, Kate Tilling, Karen Luyt, Nicholas Timpson, Julian P. T. Higgins

Published in: Systematic Reviews | Issue 1/2016

Login to get access

Abstract

Background

The parameters of the optic disc and peripapillary retinal nerve fibre layer (pRNFL) in premature children may vary with disease processes that contribute to visual impairment and blindness and so could be useful as an objective measure in at-risk children.

Methods

A systematic review of current literature on the range of pRNFL and optic disc parameters in children aged less than 18 years, who were born before 37 weeks gestation, will be performed. The bibliographic databases MEDLINE, CINAHL, EMBASE, Scopus and Web of Science will be systematically searched. Where possible and appropriate, study-specific estimates will be combined using meta-analysis to obtain an overall summary estimate of pRNFL thickness and cup-disc ratio across studies, and results will be presented by age of population.

Discussion

This review aims to improve understanding of what might be considered within/outside the range of normality for this high-risk group.

Systematic review registration

The review is registered on PROSPERO: CRD42016037933
Appendix
Available only for authorised users
Literature
1.
2.
Rudanko SL, Fellman V, Laatikainen L. Visual impairment in children born prematurely from 1972 through 1989. Ophthalmology. 2003;110(8):1639–45.CrossRefPubMed
3.
Holmstrom GE, et al. Ophthalmologic outcome at 30 months’ corrected age of a prospective Swedish cohort of children born before 27 weeks of gestation: the extremely preterm infants in Sweden study. JAMA Ophthalmol. 2014;132(2):182–9.CrossRefPubMed
4.
Tornqvist K, Ericsson A, Kallen B. Optic nerve hypoplasia: risk factors and epidemiology. Acta Ophthalmol Scand. 2002;80(3):300–4.CrossRefPubMed
5.
Wang J, et al. Characteristics of peripapillary retinal nerve fiber layer in preterm children. Am J Ophthalmol. 2012;153(5):850–5.CrossRefPubMed
6.
Park KA, Oh SY. Retinal nerve fiber layer thickness in prematurity is correlated with stage of retinopathy of prematurity. Eye. 2015;29(12):1594–602.CrossRefPubMedPubMedCentral
7.
Wang J, et al. Critical period for foveal fine structure in children with regressed retinopathy of prematurity. Retina. 2012;32(2):330–9.CrossRefPubMed
8.
Tariq YM, et al. Association of birth parameters with OCT measured macular and retinal nerve fiber layer thickness. Invest Ophthalmol Vis Sci. 2011;52(3):1709–15.CrossRefPubMed
9.
Akerblom H, et al. Retinal nerve fibre layer thickness in school-aged prematurely-born children compared to children born at term. Br J Ophthalmol. 2012;96(7):956–60.CrossRefPubMed
10.
Lim MC, et al. Effect of diabetic retinopathy and panretinal photocoagulation on retinal nerve fiber layer and optic nerve appearance. Arch Ophthalmol. 2009;127(7):857–62.CrossRefPubMed
11.
Muqit MM, et al. Effects of conventional argon panretinal laser photocoagulation on retinal nerve fibre layer and driving visual fields in diabetic retinopathy. Eye (Lond). 2010;24(7):1136–42.CrossRef
12.
Wang D, et al. Localized retinal nerve fiber layer defects and stroke. Stroke. 2014;45(6):1651–6.CrossRefPubMed
13.
Park HY, et al. Transneuronal retrograde degeneration of the retinal ganglion cells in patients with cerebral infarction. Ophthalmology. 2013;120(6):1292–9.CrossRefPubMed
14.
Rufa A, et al. Retinal nerve fiber layer thinning in CADASIL: an optical coherence tomography and MRI study. Cerebrovasc Dis. 2011;31(1):77–82.CrossRefPubMed
15.
Parisi V, et al. Reduction of optic nerve fiber layer thickness in CADASIL. Eur J Neurol. 2007;14(6):627–31.CrossRefPubMed
16.
Sriram P, et al. Relationship between optical coherence tomography and electrophysiology of the visual pathway in non-optic neuritis eyes of multiple sclerosis patients. PLoS One. 2014;9(8):e102546.CrossRefPubMedPubMedCentral
17.
Galetta KM, et al. Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration. Neurotherapeutics. 2011;8(1):117–32.CrossRefPubMedPubMedCentral
18.
19.
Boluyt N, et al. Usefulness of systematic review search strategies in finding child health systematic reviews in MEDLINE. Arch Pediatr Adolesc Med. 2008;162(2):111–6.CrossRefPubMed
20.
21.
Schippling S, et al. Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria. Mult Scler. 2015;21(2):163–70.CrossRefPubMed
Metadata
Title
The range of peripapillary retinal nerve fibre layer and optic disc parameters, in children aged up to but not including 18 years of age who were born prematurely: protocol for a systematic review
Authors
Alexandra L. Creavin
Cathy E. M. Williams
Kate Tilling
Karen Luyt
Nicholas Timpson
Julian P. T. Higgins
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2016
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-016-0319-0

Other articles of this Issue 1/2016

Systematic Reviews 1/2016 Go to the issue

Protocol

Effectiveness and content analysis of interventions to enhance medication adherence in hypertension: a systematic review and meta-analysis protocol

Protocol

Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review

Protocol

Effectiveness of eHealth interventions for the promotion of physical activity in older adults: a systematic review protocol

Protocol

Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research

Research

Telemedicine with clinical decision support for critical care: a systematic review

Protocol

The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review protocol