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Rheumatology International
Published in: Rheumatology International 5/2007

01-03-2007 | Letter to the Editor

The prevalence of Tropheryma whippelii DNA in saliva from healthy controls and patients with spondyloarthropathy

Authors: Jin-Wuk Hur, Young-In Na, Tae-Hwan Kim, Shin-Young Yim, Jae-Bum Jun

Published in: Rheumatology International | Issue 5/2007

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Excerpt

Whipple’s disease (WD) is a chronic infectious disorder of multi-system caused by Tropheryma whippelii (TW). Although the prominent symptoms are diarrhea, malabsorption, and weight loss, the arthritis may precede the gastrointestinal symptoms [1]. Furthermore, some cases of WD shows the clinical manifestations of spondyloarthropathy (SpA), such as oligoarthritis pattern, axial involvement, sacroiliitis, and association with HLA-B27 [2]. …
Literature
1.
Dutly F, Altwegg M (2001) Whipple’s disease and Tropheryma whippelii. Clin Microbiol Rev 14:561–583PubMedCrossRef
2.
Sanmarti R, Canete JD, Salvador G (2004) Palindromic rheumatism and other relapsing arthritis. Best Pract Res Clin Rheumatol 18:647–661PubMedCrossRef
3.
Hinrikson HP, Dutly F, Altwegg M (2000) Evaluation of a specific nested PCR targeting domain III of the 23S rRNA gene of Tropheryma whippelii and proposal of a classification system for its molecular variants. J Clin Microbiol 38:595–599PubMed
4.
Street S, Donoghue HD, Neild GH (1999) Tropheryma whippelii DNA in saliva of healthy people. Lancet 354:1178–1179PubMedCrossRef
5.
Ehrbar HU, Bauerfeind P, Dutly F, Koelz HR, Altwegg M (1999) PCR-positive tests for Tropheryma whippelii in patients without Whipple’s disease. Lancet 353:2214PubMedCrossRef
6.
Puechal X, Schaeverbeke T, Sibilia J, Saraux A, Poveda JD (2002) Polymerase chain reaction testing for Tropheryma whippelii in unexplained isolated cases of arthritis. Arthritis Rheum 46:1130–1132PubMedCrossRef
Metadata
Title
The prevalence of Tropheryma whippelii DNA in saliva from healthy controls and patients with spondyloarthropathy
Authors
Jin-Wuk Hur
Young-In Na
Tae-Hwan Kim
Shin-Young Yim
Jae-Bum Jun
Publication date
01-03-2007
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 5/2007
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-006-0231-3

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