Skip to main content
Top
Published in: Perioperative Medicine 1/2017

Open Access 01-12-2017 | Research

The prevalence of pulmonary complications after thoracic and abdominal surgery and associated risk factors in patients admitted at a government hospital in Harare, Zimbabwe-a retrospective study

Authors: Cathrine Tadyanemhandu, Rufaro Mukombachoto, Clement Nhunzvi, Farayi Kaseke, Vasco Chikwasha, Samson Chengetanai, Shamila Manie

Published in: Perioperative Medicine | Issue 1/2017

Login to get access

Abstract

Background

The burden of HIV/AIDS in Sub-Saharan Africa has presented unusual and challenging acute surgical problems across all specialties. Thoraco-abdominal surgery cuts through muscle and thereby disrupts the normal anatomy and activity of the respiratory muscles leading to reduced lung volumes and putting the patients at greater risk of developing post-operative pulmonary complications (PPCs). PPCs remain an important cause of post-operative morbidity, mortality, and impacts on the long-term outcomes of patients post hospital discharge. The objective of the study was to determine the pulmonary complications developing after abdominal and thoracic surgery and the associated risks factors.

Methods

A retrospective records review of all abdominal and thoracic surgery patients admitted at a central hospital from January 2014 to October 2014 was done. Data collected included demographic data, surgical history, comorbidities and the PPCs present.

Results

Out of the 92 patients whose records were reviewed, 55 (59.8%) were males and 84 (91.3%) had abdominal surgery. The mean age of the patients was 42.6 years (SD = 18.4). The common comorbidities were HIV infection noted in 14(15.2%) of the patients and hypertension in 10 (13.0%). Thirty nine (42.4%) developed PPCs and the most common complications were nosocomial pneumonia in 21 (22.8%) patients, ventilator associated pneumonia in 11 (12.0%), and atelectasis in 6 (6.5%) patients. Logistic regression showed that a history of alcohol consumption, prolonged surgery, prolonged stay in hospital or critical care unit, incision type, and comorbidities were significant risk factors for PPCs (p < 0.05). The mortality rate was 10.9%.

Conclusion

PPCs like nosocomial and ventilator associated pneumonia were common and were associated with increased morbidity and adversely affected clinical outcomes of patients. HIV and hypertension presented significant comorbidities which the health team needed to recognize and address. Strategies to reduce the occurrence of PPCs have to be implemented through coordinated efforts by the health practitioners as a team during the entire perioperative period.
Literature
go back to reference Ärnlöv J. Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the global burden of disease study 2015. The Lancet HIV. 2016;3(8):E361–87.CrossRefPubMed Ärnlöv J. Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the global burden of disease study 2015. The Lancet HIV. 2016;3(8):E361–87.CrossRefPubMed
go back to reference Arozullah AM, Khuri SF, Henderson WG, Daley J. Development and validation of a multifactorial risk index for predicting postoperative pneumonia after major non-cardiac surgery. Ann Intern Med. 2001;135:847–57.CrossRefPubMed Arozullah AM, Khuri SF, Henderson WG, Daley J. Development and validation of a multifactorial risk index for predicting postoperative pneumonia after major non-cardiac surgery. Ann Intern Med. 2001;135:847–57.CrossRefPubMed
go back to reference Bhat SA, Shinde V, Chaudhari L. Audit of intensive care unit admissions from the operating room. Indian Journal of Anesth. 2006;50(6):193–200. Bhat SA, Shinde V, Chaudhari L. Audit of intensive care unit admissions from the operating room. Indian Journal of Anesth. 2006;50(6):193–200.
go back to reference Chalya PL, Gilyoma JM, Dass RM, Mchembe MD, Matasha M, Mabula JB, Mbelenge N, Mahalu W. Trauma admissions to the intensive care unit at a reference hospital in northwestern Tanzania. Scandinavian journal of trauma, resuscitation and. Emerg Med. 2011;19:61. Chalya PL, Gilyoma JM, Dass RM, Mchembe MD, Matasha M, Mabula JB, Mbelenge N, Mahalu W. Trauma admissions to the intensive care unit at a reference hospital in northwestern Tanzania. Scandinavian journal of trauma, resuscitation and. Emerg Med. 2011;19:61.
go back to reference Fisher BW, Majumdar SR, McAlister FA. Predicting pulmonary complications after nonthoracic surgery: a systematic review of blinded studies. Am J Med. 2002;112:219–25.CrossRefPubMed Fisher BW, Majumdar SR, McAlister FA. Predicting pulmonary complications after nonthoracic surgery: a systematic review of blinded studies. Am J Med. 2002;112:219–25.CrossRefPubMed
go back to reference Frankel H, Sperry J, Kaplan L, Foley A, Rabinovici R. Classification of adverse events occurring in a surgical intensive care unit. Am J Surg. 2007;194:328–32.CrossRefPubMed Frankel H, Sperry J, Kaplan L, Foley A, Rabinovici R. Classification of adverse events occurring in a surgical intensive care unit. Am J Surg. 2007;194:328–32.CrossRefPubMed
go back to reference Grimes CE, Law RSL, Borgstein ES, Mkandawire NC, Lavy CBD. Systematic review of met and unmet need of surgical disease in rural sub-Saharan Africa. World J Surg. 2012;36:8–23.CrossRefPubMed Grimes CE, Law RSL, Borgstein ES, Mkandawire NC, Lavy CBD. Systematic review of met and unmet need of surgical disease in rural sub-Saharan Africa. World J Surg. 2012;36:8–23.CrossRefPubMed
go back to reference Hanekom S, Coetzee AR, Faure M. Outcome evaluation of a south African surgical ICU—a baseline study. South African Journal of Critical Care. 2006;22(1):14–20. Hanekom S, Coetzee AR, Faure M. Outcome evaluation of a south African surgical ICU—a baseline study. South African Journal of Critical Care. 2006;22(1):14–20.
go back to reference Hulzebos EH, Van Meeteren NL, De Bie RA, Dagnelie PC, Helders PJ. Prediction of postoperative pulmonary complications on the basis of preoperative risk factors in patients who had undergone coronary artery bypass graft surgery. Phys Ther. 2003;83(1):8–16.PubMed Hulzebos EH, Van Meeteren NL, De Bie RA, Dagnelie PC, Helders PJ. Prediction of postoperative pulmonary complications on the basis of preoperative risk factors in patients who had undergone coronary artery bypass graft surgery. Phys Ther. 2003;83(1):8–16.PubMed
go back to reference Inoue J, Ono R, Makiura D, Kashiwa-Motoyama M, Miura Y, Usami M, Nakamura T, Imanishi T, Kuroda D. Prevention of postoperative pulmonary complications through intensive preoperative respiratory rehabilitation in patients with esophageal cancer. Disease of the Esophagus. 2013;26:68–74.CrossRef Inoue J, Ono R, Makiura D, Kashiwa-Motoyama M, Miura Y, Usami M, Nakamura T, Imanishi T, Kuroda D. Prevention of postoperative pulmonary complications through intensive preoperative respiratory rehabilitation in patients with esophageal cancer. Disease of the Esophagus. 2013;26:68–74.CrossRef
go back to reference Jammer I, Wickboldt N, Sander M, Smith A, Schultz MJ, Pelosi P, Leva B, Rhodes A, Hoeft A, Walder B, Chew MS, Pearse RP. Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative clinical outcome (EPCO) definitions. A statement from the ESA-ESICM joint taskforce on perioperative outcome measures. Eur J Anaesthesiol. 2015;32:88–105.CrossRefPubMed Jammer I, Wickboldt N, Sander M, Smith A, Schultz MJ, Pelosi P, Leva B, Rhodes A, Hoeft A, Walder B, Chew MS, Pearse RP. Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine: European Perioperative clinical outcome (EPCO) definitions. A statement from the ESA-ESICM joint taskforce on perioperative outcome measures. Eur J Anaesthesiol. 2015;32:88–105.CrossRefPubMed
go back to reference Jensen L, Yang L. Risk factors for postoperative pulmonary complications in coronary artery bypass graft surgery patients. Eur J Cardiovasc Nurs. 2007;6:241–6.CrossRefPubMed Jensen L, Yang L. Risk factors for postoperative pulmonary complications in coronary artery bypass graft surgery patients. Eur J Cardiovasc Nurs. 2007;6:241–6.CrossRefPubMed
go back to reference Kodra N, Shpata V, Ohri I. Risk factors for postoperative pulmonary complications after abdominal surgery. Open Access Maced J Med Sci. 2016;4(2):259–63.CrossRefPubMedPubMedCentral Kodra N, Shpata V, Ohri I. Risk factors for postoperative pulmonary complications after abdominal surgery. Open Access Maced J Med Sci. 2016;4(2):259–63.CrossRefPubMedPubMedCentral
go back to reference Nthumba PM, Juma PI. HIV infection: implications on surgical practice, HIV-infection - impact, awareness and social implications of living with HIV/AIDS, 2011. Eugenia Barros (Ed.), ISBN: 978-953- 307-343-9. Nthumba PM, Juma PI. HIV infection: implications on surgical practice, HIV-infection - impact, awareness and social implications of living with HIV/AIDS, 2011. Eugenia Barros (Ed.), ISBN: 978-953- 307-343-9.
go back to reference Odimba BFK. The impact of HIV infection on the surgical disease burden in Africa. East and Central Journal of Surgery. 2010;15(1):3–8. Odimba BFK. The impact of HIV infection on the surgical disease burden in Africa. East and Central Journal of Surgery. 2010;15(1):3–8.
go back to reference Okafor UV. An audit of unplanned postoperative intensive care unit admissions in Enugu, Nigeria: causes and outcome. South African Journal of Critical Care. 2009;25:1. Okafor UV. An audit of unplanned postoperative intensive care unit admissions in Enugu, Nigeria: causes and outcome. South African Journal of Critical Care. 2009;25:1.
go back to reference Pandie M, van der Plas H, Maartens G, Mendelson M. The role of the infectious diseases unit at Groote Schuur hospital in addressing South Africa’s greatest burden of disease. S Afr Med J. 2012;102(6):528–31.CrossRefPubMed Pandie M, van der Plas H, Maartens G, Mendelson M. The role of the infectious diseases unit at Groote Schuur hospital in addressing South Africa’s greatest burden of disease. S Afr Med J. 2012;102(6):528–31.CrossRefPubMed
go back to reference Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, Spies C, Vallet B, Vincent JL, Hoeft A, Rhodes A, for the European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology. Mortality after surgery in Europe: a 7 day cohort study. Lancet. 2012;380:1059–65.CrossRefPubMedPubMedCentral Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, Spies C, Vallet B, Vincent JL, Hoeft A, Rhodes A, for the European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology. Mortality after surgery in Europe: a 7 day cohort study. Lancet. 2012;380:1059–65.CrossRefPubMedPubMedCentral
go back to reference Qaseem A, Snow V, Fitterman N, Hornbake ER, Lawrence VA, Smetana GW, Weiss K, Owens DK. Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: a guideline from the American College of Physicians. Ann Intern Med. 2006;144:575–80.CrossRefPubMed Qaseem A, Snow V, Fitterman N, Hornbake ER, Lawrence VA, Smetana GW, Weiss K, Owens DK. Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: a guideline from the American College of Physicians. Ann Intern Med. 2006;144:575–80.CrossRefPubMed
go back to reference Reeve J. Physiotherapy interventions to prevent postoperative pulmonary complications following lung resection. What is the evidence? What is the practice? N Z J Physiother. 2008;36(3):118–30. Reeve J. Physiotherapy interventions to prevent postoperative pulmonary complications following lung resection. What is the evidence? What is the practice? N Z J Physiother. 2008;36(3):118–30.
go back to reference Romig MC, Dorman T. Opening your eyes to postoperative pulmonary complications. Crit Care Med. 2011;39:9.CrossRef Romig MC, Dorman T. Opening your eyes to postoperative pulmonary complications. Crit Care Med. 2011;39:9.CrossRef
go back to reference Rudra A, Das S. Postoperative pulmonary complications. Indian Journal of Anesthetics. 2006;50(2):89–98. Rudra A, Das S. Postoperative pulmonary complications. Indian Journal of Anesthetics. 2006;50(2):89–98.
go back to reference Sawyer R, Leon A. Common complications in the surgical intensive care unit. Crit Care Med. 2010;38:9.CrossRef Sawyer R, Leon A. Common complications in the surgical intensive care unit. Crit Care Med. 2010;38:9.CrossRef
go back to reference Semer NB, Sullivan SR, Meara JG. Plastic surgery and global health: how plastic surgery impacts the global burden of surgical disease. J Plast Reconstr Aesthet Surg. 2010;63(8):1244–8.CrossRefPubMed Semer NB, Sullivan SR, Meara JG. Plastic surgery and global health: how plastic surgery impacts the global burden of surgical disease. J Plast Reconstr Aesthet Surg. 2010;63(8):1244–8.CrossRefPubMed
go back to reference Sharafkhaneh A, Falk JA, Minai OA, Lipson DA. Overview of the perioperative management of lung volume reduction surgery patients. Proc Am Thorac Soc. 2008;5:438–41.CrossRefPubMedPubMedCentral Sharafkhaneh A, Falk JA, Minai OA, Lipson DA. Overview of the perioperative management of lung volume reduction surgery patients. Proc Am Thorac Soc. 2008;5:438–41.CrossRefPubMedPubMedCentral
go back to reference Smetana GW. Postoperative pulmonary complications: an update on risk assessment and reduction. Cleve Clin J Med. 2009;76(suppl 4):S60–5.CrossRefPubMed Smetana GW. Postoperative pulmonary complications: an update on risk assessment and reduction. Cleve Clin J Med. 2009;76(suppl 4):S60–5.CrossRefPubMed
go back to reference Tadyanemhandu C, Manie S. Profile of patients and physiotherapy patterns in intensive care units in public hospitals in Zimbabwe: a descriptive cross-sectional study. BMC Anesthesiol. 2015;15:136.CrossRefPubMedPubMedCentral Tadyanemhandu C, Manie S. Profile of patients and physiotherapy patterns in intensive care units in public hospitals in Zimbabwe: a descriptive cross-sectional study. BMC Anesthesiol. 2015;15:136.CrossRefPubMedPubMedCentral
Metadata
Title
The prevalence of pulmonary complications after thoracic and abdominal surgery and associated risk factors in patients admitted at a government hospital in Harare, Zimbabwe-a retrospective study
Authors
Cathrine Tadyanemhandu
Rufaro Mukombachoto
Clement Nhunzvi
Farayi Kaseke
Vasco Chikwasha
Samson Chengetanai
Shamila Manie
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Perioperative Medicine / Issue 1/2017
Electronic ISSN: 2047-0525
DOI
https://doi.org/10.1186/s13741-017-0066-3

Other articles of this Issue 1/2017

Perioperative Medicine 1/2017 Go to the issue